59 Results for "

phosphatidylethanolamine

" in MedChemExpress (MCE) Product Catalog:
Products (59)

59 Results for "phosphatidylethanolamine" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-W583868
CAS No.: 26662-94-2
Synonyms: 1,2-POPE; 16:0-18:1 PE
1-Palmitoyl-2-oleoyl-sn-glycero-3-PE (1,2-POPE; 16:0-18:1 PE) is a phosphatidylethanolamine (PE) lipid. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can induce lipid bilayer to form a hexagonal phase (HII) structure in an acidic environment and promote membrane fusion. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can enhance the endosomal escape ability of lipid nanoparticles (LNPs) and improve the cellular delivery efficiency of nucleic acid drugs such as mRNA. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can be used for LNP carrier targeting of gene therapy and mRNA vaccines .
loading...
    loading...
Cat. No.: HY-P1695
CAS No.: 110655-58-8
Synonyms: Ro 09-0198
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Cinnamycin (Ro 09-0198) is a tetracyclic peptide antibiotic that binds specifically to phosphatidylethanolamine (PE) .
loading...
    loading...
Cat. No.: HY-112747
CAS No.: 97281-51-1
Synonyms: LPI; PE (soy)
Target:  

Phospholipase

Research Areas:  

Infection

Soy PE (LPI) is the most abundant phospholipid in prokaryotes and the second most abundant found in the membrane of mammalian, plant, and yeast cells, comprising approximately 25% of total mammalian phospholipids. In the brain, phosphatidylethanolamine comprises almost half of the total phospholipids. It is synthesized mainly through the cytidine diphosphate-ethanolamine and phosphatidylserine decarboxylation pathways, which occur in the endoplasmic reticulum (ER) and mitochondrial membranes, respectively. It is a precursor in the synthesis of phosphatidylcholine and arachidonoyl ethanolamide and is a source of ethanolamine used in various cellular functions. In E.coli, phosphatidylethanolamine deficiency prevents proper assembly of lactose permease, suggesting a role as a lipid chaperone. It is a cofactor in the propagation of prions in vitro and can convert recombinant mammalian proteins into infectious molecules even in the absence of RNA. This product contains phosphatidylethanolamine molecular species with variable fatty acyl chain lengths at the sn-1 and sn-2 positions .
loading...
    loading...
Cat. No.: HY-106302
CAS No.: 1391-36-2
Purity:  99.46%
Synonyms: Moli1901; Lancovutide
Duramycin (Moli1901) is a lantibiotic derived from Streptomyces cinnamoneuma. Duramycin also is a antimicrobial peptide. Duramycin can be used for the research of cystic fibrosis (CF) .
loading...
    loading...
Cat. No.: HY-112766
CAS No.: 201036-16-0
Purity:  ≥98.0%
Target:  

Liposome

Research Areas:  

Others

DPyPE is a neutral phosphatidylethanolamine lipid composed of a polyisoprene alkyl chain with two pyridine-containing phosphine ligands. DPyPE is mainly used in liposome formulations and to enhance the efficiency of gene delivery in vitro and in vivo. For example, DPyPE can be mixed with cationic lipids such as VC1052 (HY-156616) (in a 1:1 ratio) to form the vaccine adjuvant Vaxfectin (HY-142998). DPyPE assists VC1052 in binding to negatively charged pDNA to form a uniform liposome complex by regulating the fluidity and stability of the liposome membrane .
loading...
    loading...
Cat. No.: HY-144012
CAS No.: 474922-84-4
Purity:  99.83%
Synonyms: 16:0 PEG2000 PE ammonium; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] ammonium
DPPE-PEG2000 ammonium (16:0 PEG5000 PE) is a polymer-lipid conjugate and LipoParticle stabilizer with a PEG chain of 5,000 g/mol molecular weight attached to its polar head, and it can be internalized by biological membranes. DPPE-PEG2000 ammonium enables LipoParticle to maintain colloidal stability after 20-fold dilution in PBS or cell culture medium, and prevents aggregate formation during lyophilization and rehydration. DPPE-PEG2000 ammonium helps enhance the non-cytotoxic property of LipoParticle formulations against human osteoblasts. DPPE-PEG2000 ammonium serves as a PEG lipid functional end group for synthesizing liposomes (LPs), is used in the design of conjugated polymer nanoparticles, and applies to research related to bone and joint infections .
loading...
    loading...
Cat. No.: HY-124370
CAS No.: 13058-52-1
Purity:  99.2%
Synonyms: 9Z,11E-CLA; Methyl 9(Z),11(E)-octadecadienoate; (9Z,11E)-SFE 19:2
Target:  

Endogenous Metabolite

Research Areas:  

Cardiovascular Disease Cancer

9 (Z),11 (E)-Conjugated linoleic acid methyl ester (9Z,11E-CLA; Methyl 9 (Z),11 (E)-octadecadienoate; (9Z,11E)-SFE 19:2) is an isomer of Linoleic acid (HY-N0729), and is a conjugated linoleic acid mainly found in meat and dairy products. Conjugated linoleic acid is a bioactive fatty acid that improves body composition, enhances immune system function, and exhibits anti-cancer and anti-atherosclerotic effects .
loading...
    loading...
Cat. No.: HY-174940
CAS No.: 1240502-50-4
E. coli Extract Polar is a polar lipid extract of Escherichia coli containing phosphatidylethanolamine, phosphatidylglycerol, and cardiolipin for reconstitution of membrane proteins.
loading...
    loading...
Cat. No.: HY-N7327
CAS No.: 50276-96-5
Ochnaflavone is an inhibitor of IIA-type secretory phospholipase A2 (sPLA2-IIA) with an IC50 of 3.45 µM. Ochnaflavone exhibits significant anti-inflammatory and liver-protective effects, capable of inhibiting the degradation of phosphatidylethanolamine (PE) and lipid peroxidation induced by carbon tetrachloride (CCl4) in rat liver, with an IC50 of 7.16 µM for lipid peroxidation. Ochnaflavone can be used in research on liver damage and inflammatory diseases .
loading...
    loading...
Cat. No.: HY-120991
CAS No.: 26662-95-3
Purity:  ≥98.0%
Synonyms: 1-Palmitoyl-2-linoleoyl PE; (1-Palmitoyl, 2-linoleoyl)-phosphatidylethanolamine; (1-Palmitoyl, 2-linoleoyl)-phosphoethanolamine
Target:  

Liposome

Research Areas:  

Others

1-Palmitoyl-2-linoleoyl-sn-glycero-3-PE (1-Palmitoyl-2-linoleoyl PE) is a lipid, which promotes nucleic acid such as sRNA to absorb and enter the target cell .
loading...
    loading...
Cat. No.: HY-N15936
CAS No.: 2936622-21-6
a15:0-i15:0 PE is a diacyl phosphatidylethanolamine with two branched chains. a15:0-i15:0 PE is a non-canonical TLR2-TLR1 heterodimer agonist and has immunogenic activity. a15:0-i15:0 PE activates T cells and DC signaling and shows anti-inflammatory activity. a15:0-i15:0 PE induces TNFα and IL-6 production. a15:0-i15:0 PE is a the major component (approximately 50%) of A. muciniphila’s lipid membrane .
loading...
    loading...
Cat. No.: HY-143203
CAS No.: 7266-53-7
Purity:  ≥98.0%
Synonyms: 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine
18:0-18:2 PE is an important component of phosphatidylethanolamine (PE), involved in phospholipid metabolism and associated with diseases such as ovarian cancer. 18:0-18:2 PE in the hot processing process, its unsaturated fatty acids will degrade to form a variety of odor active compounds. 18:0-18:2 PE is mainly used in the field of food science to improve the flavor of aquatic products, as well as medical research on diseases related to phospholipid metabolism .
loading...
    loading...
Cat. No.: HY-W800805
CAS No.: 2295813-15-7
Target:  

Liposome

Research Areas:  

Cancer

DOPE-Mal is an N-maleimide-derived phosphatidylethanolamine. DOPE-Mal does not interfere with fatty acyl chains or alter lipid bilayer permeability; it increases lipid bilayer order, reduces fluidity, induces conformational changes in phospholipid polar heads and enhances their hydration. DOPE-Mal can be used as a component to prepare maleimide-displaying liposomes, enabling peptide conjugation via maleimide-thiol coupling. DOPE-Mal can be used to prepare Liposomes for delivering Doxorubicin (HY-15142A) to hepatocytes. DOPE-Mal is applicable to research related to hepatocellular carcinoma and lung cancer .
loading...
    loading...
Cat. No.: HY-147071
CAS No.: 5634-86-6
Synonyms: DAPE
Target:  

Liposome

Research Areas:  

Metabolic Disease

1,2-Diarachidonoyl-sn-glycero-3-phosphoethanolamine (DAPE) is a phospholipid phosphatidylethanolamine. Unlike other phospholipid phosphatidylethanolamines, 1,2-Diarachidonoyl-sn-glycero-3-phosphoethanolamine has no significant effect on protein phosphatase PP2A activity and does not inhibit insulin-stimulated GLUT4 translocation .
loading...
    loading...
Cat. No.: HY-145780
CAS No.: 3036-18-8
Purity:  99.29%
Target:  

Cholinesterase (ChE)

Research Areas:  

Others

Cytidine 5′-diphosphoethanolamine is an intermediate compound in the synthesis of phosphatidylethanolamine. Cytidine 5′-diphosphoethanolamine is a stimulant of Ach synthesis .
loading...
    loading...
Cat. No.: HY-130323
CAS No.: 67597-26-6
Target:  

Bacterial

Research Areas:  

Infection

13-HPOT is a linolenic acid hydroperoxide and an antibacterial agent. 13-HPOT interacts with lipid representatives of bacterial inner membranes. 13-HPOT exerts dose-dependent in vitro antibacterial activity against Pectobacterium carotovorum, Pseudomonas syringae pv. syringae DC3000, and Xanthomonas translucens pv. translucens .
loading...
    loading...
Cat. No.: HY-D1556
CAS No.: 384832-91-1
Synonyms: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(carboxyfluorescein) ammonium
18:1 PE CF (1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(carboxyfluorescein) (ammonium)) is a pH-sensitive fluorescent indicator. 18:1 PE CF exhibits changes in fluorescence intensity in response to pH variations and reflects the electrostatic states of cationic liposomes and lipoplexes. 18:1 PE CF supports real-time visualization of pH distribution and membrane deformation in giant unilamellar vesicles and is suitable for steady-state fluorescence testing in large unilamellar vesicle membranes. 18:1 PE CF is capable of monitoring the surface electrical potential of cationic liposomes and lipoplexes and can effectively label lipid bilayers and nanomicelles. 18:1 PE CF can be used for the research of the investigation of lung cancer (Ex = 495 nm; Em = 520 nm) .
loading...
    loading...
Cat. No.: HY-144016
CAS No.: 328250-18-6
Purity:  99.93%
16:0 EPC chloride, a P-O-ethyl derivative, is a saturated cationic lipid. 16:0 EPC chloride can serve as a DNA and RNA transfecting agent. 16:0 EPC chloride can be used as a co-adjuvant for preparing vaccines and promote drug delivery .
loading...
    loading...
Cat. No.: HY-W923150
CAS No.: 140219-78-9
Research Areas:  

Metabolic Disease

1,2-Diheptadecanoyl-sn-glycero-3-phosphatidylethanolamine is an ester product.
loading...
    loading...
Cat. No.: HY-166874
DSPE-PEG2000-endo-BCN is a PEG-lipid conjugate and distearyl phosphatidylethanolamine-polyethylene glycol (DSPE-PEG) derivative. DSPE-PEG2000-endo-BCN improves the delivery efficiency and tissue specificity of poorly soluble drugs and can be used in drug delivery research .
loading...
    loading...