1. Anti-infection
  2. Bacterial
    Antibiotic
  3. Cinnamycin

Cinnamycin (Synonyms: Ro 09-0198)

Cat. No.: HY-P1695
Handling Instructions

Cinnamycin is tetracyclic lantibiotic produced from S. cinnamoneus that contains four unusual amino acids: erythro-β-hydroxyaspartic acid, mesolanthionine, threo-β-methyllanthionine, and lysinoalanine.1 Cinnamycin has demonstrated antiviral activity against herpes simplex virus type 1 KOS strain infection in Vero cells via a cytopathic effect reduction assay. Cinnamycin recognizes the structure of phosphatidylethanolamine and forms an equimolar complex with the phospholipid on biological membranes. This peptide has been used as a probe for analyzing the transbilayer movement of phosphatidylethanolamine.

For research use only. We do not sell to patients.

Cinnamycin Chemical Structure

Cinnamycin Chemical Structure

CAS No. : 110655-58-8

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Description

Cinnamycin is tetracyclic lantibiotic produced from S. cinnamoneus that contains four unusual amino acids: erythro-β-hydroxyaspartic acid, mesolanthionine, threo-β-methyllanthionine, and lysinoalanine.1 Cinnamycin has demonstrated antiviral activity against herpes simplex virus type 1 KOS strain infection in Vero cells via a cytopathic effect reduction assay. Cinnamycin recognizes the structure of phosphatidylethanolamine and forms an equimolar complex with the phospholipid on biological membranes. This peptide has been used as a probe for analyzing the transbilayer movement of phosphatidylethanolamine.

Molecular Weight

2041.30

Formula

C₈₉H₁₂₅N₂₅O₂₅S₃

CAS No.

110655-58-8

Sequence

Cys-Arg-Gln-Cys-Cys-Ala-Phe-Gly-Pro-Phe-{Abu}-Phe-Val-Cys-Asp-Gly-Asn-{Abu}-Lys (Sulfide bridge: Cys1-Abu18, Cys4-Cys14, Cys5-Abu11)

Sequence Shortening

CRQCCAFGPF-{Abu}-FVCDGN-{Abu}-K (Sulfide bridge:Cys1-Xaa18;Cys4-Cys14;Cys5-Xaa11)

SMILES

[Cys-Arg-Gln-Cys-Cys-Ala-Phe-Gly-Pro-Phe-{Abu}-Phe-Val-Cys-Asp-Gly-Asn-{Abu}-Lys (Sulfide bridge: Cys1-Abu18, Cys4-Cys14, Cys5-Abu11)]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

CinnamycinRo 09-0198BacterialAntibioticInhibitorinhibitorinhibit

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