1. Metabolic Enzyme/Protease Apoptosis
  2. Phosphatase Apoptosis
  3. 1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine

1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine  (Synonyms: 16:1 PE)

Cat. No.: HY-157673 Purity: 99%
Handling Instructions Technical Support

1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine (16:1 PE) is a phosphatidylethanolamine that can enhance PP2A and PTP1B activities in malignant pleural mesothelioma cells. 1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine induces apoptosis of NCI-H28 malignant pleural mesothelioma cells.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine

1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine 화학구조

CAS No. : 61599-23-3

사이즈 가격 재고 수량
1 mg 해외재고보유
5 mg 해외재고보유
10 mg 해외재고보유
50 mg   견적 받기  
100 mg   견적 받기  

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

Top Publications Citing Use of Products
  • Biological Activity

  • 순도&문서

  • References

  • 고객리뷰

제품 설명

1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine (16:1 PE) is a phosphatidylethanolamine that can enhance PP2A and PTP1B activities in malignant pleural mesothelioma cells. 1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine induces apoptosis of NCI-H28 malignant pleural mesothelioma cells[1].

In Vitro

1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine (DPPE; 1-100 μM; 24-48 hours) reduces NCI-H28 cell viability in a concentration-dependent manner (1-100 μM), but has no effect on Met5A (non-malignant mesothelial cells) cells[1].
1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine (DPPE; 100 μM; 10-60 minutes) tends to attenuate activity ofERK1/ERK2[1].
1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine (DPPE; 30-100 μM; 48 hours) significantly increases TUNEL-positive NCI-H28 cells, indicating apoptosis, with minimal effect on Met5A[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: NCI-H28 (Malignant pleural mesothelioma)
Concentration: 1 μM, 10 μM, 100 μM
Incubation Time: 24 hours, 48 hours
Result: Reduced NCI-H28 cell viability in a concentration-dependent manner.

Western Blot Analysis[1]

Cell Line: NCI-H28 (Malignant pleural mesothelioma)
Concentration: 100 μM
Incubation Time: 10 minutes, 30 minutes, 60 minutes
Result: Attenuated phosphorylation of ERK1/2 in NCI-H28 cells.

Apoptosis Analysis[1]

Cell Line: NCI-H28 (Malignant pleural mesothelioma)
Concentration: 30 and 100 μM
Incubation Time: 48 hours
Result: Induced apoptosis in NCI-H28 cells.
분자량

687.93

화학식

C37H70NO8P

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CCCCCC/C=C\CCCCCCCC(O[C@@H](COP(OCCN)(O)=O)COC(CCCCCCC/C=C\CCCCCC)=O)=O

선적

Room temperature in continental US; may vary elsewhere.

보관
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
순도&문서
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • 몰농도 계산기

  • 농도 희석 계산기

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

최근 본 상품:

온라인 문의

Your information is safe with us. * Required Fields.

상품명

 

Requested Quantity *

고객명 *

 

호칭

메일주소 *

 

전화번호 *

Department

 

회사명 *

City

Country or Region *

     

비고

대량구매 문의

Inquiry Information

상품명:
1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine
Cat. No.:
HY-157673
수량:
MCE Japan Authorized Agent: