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Cat. No.: HY-N15936

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a15:0-i15:0 PE

a15:0-i15:0 PE is a diacyl phosphatidylethanolamine with two branched chains. a15:0-i15:0 PE is a non-canonical TLR2-TLR1 heterodimer agonist and has immunogenic activity. a15:0-i15:0 PE activates T cells and DC signaling and shows anti-inflammatory activity. a15:0-i15:0 PE induces TNFα and IL-6 production. a15:0-i15:0 PE is a the major component (approximately 50%) of A. muciniphila’s lipid membrane.

For research use only. We do not sell to patients.

CAS No.: 2936622-21-6
Formula: C₃₅H₇₀NO₈P
Molecular Weight:663.91

Storage:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

a15:0-i15:0 PE Chemical Structure

CAS No.: 2936622-21-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

All Toll-like Receptor (TLR) Isoforms :

All Interleukin Related Isoforms :

Chemical Information

CAS No. 2936622-21-6
Appearance Solid
Molecular Weight 663.91
Formula C₃₅H₇₀NO₈P
Color White to off-white
SMILES

NCCOP(OC[C@H](OC(CCCCCCCCCCCC(C)C)=O)COC(CCCCCCCCCC[C@H](CC)C)=O)(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Bae M, et al. Akkermansia muciniphila phospholipid induces homeostatic immune responses. Nature. 2022 Aug;608(7921):168-173. [Content Brief]

[2]. Ghosh S, et al. A phospholipid immunomodulator from Akkermansia muciniphila. Cell Host Microbe. 2022 Sep 14;30(9):1191-1193. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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a15:0-i15:0 PE

All Toll-like Receptor (TLR) Isoforms

All Interleukin Related Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

a15:0-i15:0 PE Related Classifications

HY-N15936 Related Classifications