18:0-18:2 PE
Based on 1 Customer Validation
18:0-18:2 PE (1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine) is a glycerophospholipid compound and an essential component of biological cell membranes. 18:0-18:2 PE possesses biological activities including regulation of phospholipid metabolism, antioxidant activity, maintenance of cell membrane fluidity, immune protection, and regulation of signaling pathways. 18:0-18:2 PE in the hot processing process, its unsaturated fatty acids will degrade to form a variety of odor active compounds. 18:0-18:2 PE can be applied in food processing and research on phospholipid metabolism-related diseases.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 7266-53-7
- Formula: C41H78NO8P
- Molecular Weight:744.03
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
The interaction degree of 18:0-18:2 PE with cholesterol in the monolayer is the same as that of SM, which supports its potential role in the formation of lipid rafts in the inner layer of cell membranes[1].
18:0-18:2 PE (0.05 mM; 30 min) does not alter the oxidation product pattern of Linoleic acid (HY-N0729) in equimolar mixed liposomes of 18:0-18:2 PE and 18:0-18:2 PC (HY-126359). Under iron-initiated peroxidation, this pattern generates multiple oxidative species, among which hydroperoxides account for less than 30% of the total oxidation products[2].
Iron-driven hydroperoxide decomposition occurs in equimolar mixed liposomes of 18:0-18:2 PE and 18:0-18:2 PC pre-enriched with hydroperoxides upon treatment with 18:0-18:2 PE (0.05 mM; up to 30 min)[2].
When heated at 125 °C, 18:0-18:2 PE (1-10 mg/mL; 90-180 min) rapidly undergoes thermal oxidative degradation to form hydroperoxides, which then further decompose into non-volatile organic compounds (such as phospholipids substituted with epoxy, hydroxyl, or ketone groups) and volatile organic compounds (mainly 2-heptanone, hexanal, etc.), indicating that it is extremely susceptible to thermal oxidative damage[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 7266-53-7
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Appearance Solid
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Molecular Weight 744.03
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Formula C41H78NO8P
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Color White to off-white
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SMILES
CCCCC/C=C\C/C=C\CCCCCCCC(O[C@@H](COP(OCCN)(O)=O)COC(CCCCCCCCCCCCCCCCC)=O)=O
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Synonyms
1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
Chloroform : 125 mg/mL (168.00 mM; Need ultrasonic)
DMSO : < 1 mg/mL (insoluble or slightly soluble)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Chloroform | 1 mM | 1.3440 mL | 6.7202 mL | 13.4403 mL | 33.6008 mL |
| 5 mM | 0.2688 mL | 1.3440 mL | 2.6881 mL | 6.7202 mL | |
| 10 mM | 0.1344 mL | 0.6720 mL | 1.3440 mL | 3.3601 mL | |
| 15 mM | 0.0896 mL | 0.4480 mL | 0.8960 mL | 2.2401 mL | |
| 20 mM | 0.0672 mL | 0.3360 mL | 0.6720 mL | 1.6800 mL | |
| 25 mM | 0.0538 mL | 0.2688 mL | 0.5376 mL | 1.3440 mL | |
| 30 mM | 0.0448 mL | 0.2240 mL | 0.4480 mL | 1.1200 mL | |
| 40 mM | 0.0336 mL | 0.1680 mL | 0.3360 mL | 0.8400 mL | |
| 50 mM | 0.0269 mL | 0.1344 mL | 0.2688 mL | 0.6720 mL | |
| 60 mM | 0.0224 mL | 0.1120 mL | 0.2240 mL | 0.5600 mL | |
| 80 mM | 0.0168 mL | 0.0840 mL | 0.1680 mL | 0.4200 mL | |
| 100 mM | 0.0134 mL | 0.0672 mL | 0.1344 mL | 0.3360 mL |
18:0-18:2 PE Related Classifications
HY-143203 Related Classifications
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