2. Search Result
Search Result
Results for "

physiological+functions

" in MedChemExpress (MCE) Product Catalog:

47

Inhibitors & Agonists

4

Screening Libraries

6

Fluorescent Dye

2

Biochemical Assay Reagents

9

Peptides

10

Natural
Products

5

Isotope-Labeled Compounds

1

Click Chemistry

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B1204
    Histamine
    15+ Cited Publications

    Ergamine

    		 Histamine Receptor p38 MAPK Akt Reactive Oxygen Species (ROS) Apoptosis Endogenous Metabolite Neurological Disease Inflammation/Immunology Endocrinology Cancer
    Histamine is the agonist for histamine receptor and a vasodilator. Histamine is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma .
    Histamine
  • HY-D0989
    Rhod-2 AM
    30+ Cited Publications

    		 Fluorescent Dye Others
    Rhod-2 is a high-affinity visible light excitation wavelength Ca 2+ fluorescent probe, Rhod-2, AM is an acetyl methyl ester derivative of Rhod-2, which has cell membrane permeability and can easily enter cells with simple culture. Once it enters the cell, it is sheared by its lactesterase to produce Rhod-2 without membrane permeability, which remains in the cell to perform the corresponding physiological functions. Maximum excitation/emission wavelength: 549/578 nm .
    Rhod-2 AM
  • HY-110220
    CIM0216
    3 Publications Verification

    		 TRP Channel Neurological Disease
    CIM0216, a synthetic TRPM3 ligand, acts as a potent and selective agonist of TRPM3. CIM0216 exhibits selectivity for TRPM3 over TRPM1, TRPM2 and TRPM4-8. CIM0216 acts in a TRPM3-dependent manner to induce pain and evoke neuropeptide release from sensory nerve terminals in vitro. CIM0216 is a powerful tool for studies of the physiological functions of TRPM3, and can be used for neurogenic inflammation research .
    CIM0216
  • HY-B0722
    Histamine dihydrochloride
    15+ Cited Publications

    		 Histamine Receptor p38 MAPK Akt Reactive Oxygen Species (ROS) Apoptosis Endogenous Metabolite Neurological Disease Inflammation/Immunology Endocrinology Cancer
    Histamine dihydrochloride is the agonist for histamine receptor and a vasodilator. Histamine dihydrochloride is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine dihydrochloride affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine dihydrochloride can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma .
    Histamine dihydrochloride
  • HY-A0129
    Histamine phosphate
    15+ Cited Publications

    Histamine diphosphate

    		 Histamine Receptor p38 MAPK Akt Reactive Oxygen Species (ROS) Apoptosis Endogenous Metabolite Neurological Disease Inflammation/Immunology Endocrinology Cancer
    Histamine phosphate is the agonist for histamine receptor and a vasodilator. Histamine phosphate is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine phosphate affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine phosphate can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma .
    Histamine phosphate
  • HY-D1583
    Cyanine5 DBCO hexafluorophosphate
    4 Publications Verification

    DBCO-Cy5 hexafluorophosphate; Cyanine5 dibenzocyclooctyne hexafluorophosphate

    		 Fluorescent Dye Others
    Cyanine5 DBCO (DBCO-Cy5) hexafluorophosphate is a low-toxicity azide reactive probe (NIR fluorescent dye), for imaging azide-labeled biomolecules via a copper-free "click-through" reaction. Cyanine5 DBCO hexafluorophosphate has no apparent cytotoxicity or animal toxicity and shows no damage to the physiological functions of cells other than the target cells (azide-labeled cells). Cyanine5 DBCO hexafluorophosphate can be used to label and track cells in vitro and in vivo (Ex=635 nm, Em=650-700 nm) .
    Cyanine5 DBCO hexafluorophosphate
  • HY-159520
    Ofirnoflastum

    Ofirnoflast; HT-6184

    		 NEKs NOD-like Receptor (NLR) Caspase Apoptosis Pyroptosis NF-κB Cardiovascular Disease Inflammation/Immunology Cancer
    Ofirnoflastum (Ofirnoflast) is an orally active first-in-class allosteric NEK7 inhibitor with an IC50 of 46 nM. Ofirnoflastum binds an allosteric site adjacent to NEK7’s ATP-binding pocket, induces conformational shifts, disrupts NEK7-NLRP3 binding, blocks NLRP3 inflammasome assembly, spares NEK7’s physiological functions, and suppresses caspase-1, caspase-8, NF-κB, and TNF activity. Ofirnoflastum reduces pro-inflammatory cytokine production, suppresses ASC specks, IL-1β release, pyroptotic cell death, and leukemic burden, induces apoptosis and erythroid differentiation, restores hematopoiesis, and improves outcomes in colitis models. Ofirnoflastum can be used for the research of myelodysplastic syndromes, chronic myelomonocytic leukemia, and acute myeloid leukemia .
    Ofirnoflastum
  • HY-B1204S
    Histamine-α,α,β,β-d4 dihydrochloride

    Ergamine-α,α,β,β-d4 dihydrochloride

    		 Histamine Receptor Endogenous Metabolite Neurological Disease Endocrinology Cancer
    Histamine-α,α,β,β-d4 (dihydrochloride) is the deuterium labeled Histamine. Histamine is an organic nitrogenous compound involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.
    Histamine-α,α,β,β-d4 dihydrochloride
  • HY-150097
    Recombinant Human Serum Albumin(rHSA)

    		Biochemical Assay Reagents Metabolic Disease Inflammation/Immunology Cancer
    Recombinant Human Serum Albumin (rHSA) is a non-glycosylated monomeric plasma protein that acts as a core factor for maintaining plasma colloid osmotic pressure. Recombinant Human Serum Albumin (rHSA) possesses multiple physiological functions including carrier, metabolic regulation, detoxification, antioxidation and enzyme mimicking. Recombinant Human Serum Albumin (rHSA) not only scavenges reactive oxygen and nitrogen species via specific residues and binds a variety of endogenous and exogenous compounds to maintain redox homeostasis, but also serves as a biomarker for multiple diseases such as cancer and inflammation. Recombinant Human Serum Albumin (rHSA) broadly supports the development of implantable materials, surgical adhesives and ligand capture, and can be used for research on critical illnesses including hypovolemia, liver failure, severe sepsis and various types of trauma resuscitation .
    Recombinant Human Serum Albumin(rHSA)
  • HY-P10368
    P110 heptapeptide

    		Dynamin Reactive Oxygen Species (ROS) Infection Cardiovascular Disease Neurological Disease Inflammation/Immunology
    P110 heptapeptide is a peptide inhibitor of the Drp1-Fis1 interaction. P110 heptapeptide has anti-inflammatory, immunomodulatory, mitochondrial protective, and neuroprotective activities. Without blocking the physiological functions of Drp1, P110 heptapeptide reduces pathological functions in many models of neurodegeneration, ischemia, and sepsis. P110 heptapeptide can be used for research on neurological and inflammatory diseases .
    P110 heptapeptide
  • HY-101360
    1-EBIO

    1-Ethyl-2-benzimidazolinone

    		 Potassium Channel Neurological Disease
    1-EBIO is an activator of Ca 2+ sensitive K + channels. 1-EBIO is used to study the role of K + channels in diverse physiological functions .
    1-EBIO
  • HY-P2280
    TAT-P110

    P110

    		 Dynamin Neurological Disease Inflammation/Immunology
    TAT-P110, a peptide inhibitor of Drp1-Fis1 interaction, reduces pathology in numerous models of neurodegeneration, ischemia, and sepsis without blocking the physiological functions of Drp1 .
    TAT-P110
  • HY-B0282A
    Acetylcholine bromide
    20+ Cited Publications

    ACh bromide

    		 Biochemical Assay Reagents Others Cancer
    Acetylcholine bromide is an organic choline salt compound commonly used in neurophysiology and pharmacology experiments. It plays an important role in the nervous system, acting as a neurotransmitter that transmits signals and regulates many important physiological functions. Due to its special biological activity, Acetylcholine bromide is widely used in the study of neurotransmitters, nerve damage and muscle movement.
    Acetylcholine bromide
  • HY-101086
    Acetylcholine iodide
    Maximum Cited Publications
    24 Publications Verification

    ACh iodide

    		 Endogenous Metabolite mAChR Neurological Disease Endocrinology
    Acetylcholine iodide is a muscarinic receptor modulator. Acetylcholine iodide specifically binds to muscarinic receptors, inhibits sodium absorption, and induces chloride secretion. Acetylcholine iodide changes intestinal ion transport, enhances intestinal secretory function, induces or maintains mammary gland development and lactation. Acetylcholine iodide can be used for intestinal ion transport regulation and mammary gland physiological function research .
    Acetylcholine iodide
  • HY-DY1020
    Rhod-2 AM (solution)

    		Fluorescent Dye Others
    Rhod-2 (solution) is a high-affinity visible light excitation wavelength Ca 2+ fluorescent probe, Rhod-2, AM is an acetyl methyl ester derivative of Rhod-2, which has cell membrane permeability and can easily enter cells with simple culture. Once it enters the cell, it is sheared by its lactesterase to produce Rhod-2 without membrane permeability, which remains in the cell to perform the corresponding physiological functions. Maximum excitation/emission wavelength: 549/578 nm .
    Solvent and concentration: DMSO: 1 mM
    Rhod-2 AM (solution)
  • HY-P1345A
    TLQP-21 TFA
    2 Publications Verification

    		 Complement System Neurological Disease Endocrinology
    TLQP-21 TFA, a VGF-derived peptide endowed of endocrine and extraendocrine properties, is a potent G-protein-coupled receptor complement-3a receptor1 (C3aR1) agonist (EC50: mouse TLQP-21=10.3 μM; human TLQP-21=68.8μM). TLQP-21 TFA activates C3aR1 to induce an increase of intracellular Ca 2+. TLQP-21 TFA is used for the research in regulation of nociception and other relevant physiologic functions .
    TLQP-21 TFA
  • HY-P0070
    Thymus peptide C

    		Endogenous Metabolite Inflammation/Immunology
    Thymus peptide C is a hormonal agent derived from the thymus glands of young calves, which works as a substitute for the physiological functions of the thymus.
    Thymus peptide C
  • HY-160410
    Ceramide 3B

    		Drug Derivative Neurological Disease Inflammation/Immunology
    Ceramide 3B is a ceramide 3 lipid class with aggregation behavior. Ceramide 3B has a variety of physiological functions and can serve as a penetration enhancer and auxiliary emulsifier, playing an important role in barrier function stability .
    Ceramide 3B
  • HY-108574
    CP 339818 hydrochloride

    		Potassium Channel HCN Channel Neurological Disease
    CP 339818 hydrochloride is a non-peptide Kv1.3 channel (IC50 = 200 nM) and Kv1.4 channel blocker. CP 339818 hydrochloride inhibits HCN channel with IC50s of 18.9 μM and 43.4 μM against HCN1 and HCN4 (high Cl -). CP 339818 hydrochloride has significantly weaker blocking effects on Kv1.1, Kv1.2, Kv1.5, Kv1.6, Kv3.1-4, and Kv4.2 channels. CP 339818 hydrochloride selectively blocked Kv1.3, thereby inhibiting the activation process of human T cells. CP 339818 hydrochloride can be used to study the physiological functions of HCN and Kv channels .
    CP 339818 hydrochloride
  • HY-108498
    L-817818

    		Somatostatin Receptor Endocrinology
    L-817818 is a potent and subtype-selective agonist of the somatostatin receptor. L-817818 provides a direct approach to defining somatostatin receptor physiological functions
    L-817818
  • HY-P1238A
    Neuromedin U, rat TFA

    Neuromedin U (rat) TFA; Rat neuromedin U-23 TFA

    		 Neuromedin U Receptor (NMUR) Neurological Disease
    Neuromedin U, rat TFA is a 23-amino acid brain-gut peptide. Neuromedin U (NMU), through its cognate receptor NMUR2 in the central nervous system, regulates several important physiological functions, including energy balance, stress response, and nociception.
    Neuromedin U, rat TFA
  • HY-B1204R
    Histamine (Standard)

    Ergamine (Standard)

    		 Reference Standards Histamine Receptor p38 MAPK Akt Reactive Oxygen Species (ROS) Apoptosis Endogenous Metabolite Neurological Disease Inflammation/Immunology Endocrinology Cancer
    Histamine (Standard) is the analytical standard of Histamine (HY-B1204). This product is intended for research and analytical applications. Histamine is the agonist for histamine receptor and a vasodilator. Histamine is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma .
    Histamine (Standard)
  • HY-B0722R
    Histamine dihydrochloride (Standard)

    		Reference Standards Histamine Receptor p38 MAPK Akt Reactive Oxygen Species (ROS) Apoptosis Endogenous Metabolite Neurological Disease Inflammation/Immunology Endocrinology Cancer
    Histamine dihydrochloride (Standard) is the analytical standard of Histamine dihydrochloride (HY-B0722). This product is intended for research and analytical applications. Histamine dihydrochloride is the agonist for histamine receptor and a vasodilator. Histamine dihydrochloride is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine dihydrochloride affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine dihydrochloride can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma .
    Histamine dihydrochloride (Standard)
  • HY-P1345
    TLQP-21

    		Complement System Neurological Disease Endocrinology
    TLQP-21, a VGF-derived peptide endowed of endocrine and extraendocrine properties, is a potent G-protein-coupled receptor complement-3a receptor 1 (C3aR1) agonist (EC50: mouse TLQP-21=10.3 μM; human TLQP-21=68.8 μM). TLQP-21 activates C3aR1 to induce an increase of intracellular Ca 2+. TLQP-21 is used for the research in regulation of nociception and other relevant physiologic functions .
    TLQP-21
  • HY-B1204S1
    Histamine-d4

    Ergamine-d4

    		 Isotope-Labeled Compounds Histamine Receptor p38 MAPK Akt Reactive Oxygen Species (ROS) Apoptosis Endogenous Metabolite Neurological Disease Inflammation/Immunology Endocrinology Cancer
    Histamine-d4 (Ergamine-d4) is deuterium labeled Histamine (HY-B1204). Histamine is the agonist for histamine receptor and a vasodilator. Histamine is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma .
    Histamine-d4
  • HY-D2907
    Cyanine 5 DBCO

    DBCO-Cy5; Cyanine5 dibenzocyclooctyne

    		 Fluorescent Dye Others
    Cyanine5 DBCO (DBCO-Cy5) is a low-toxicity azide reactive probe (NIR fluorescent dye), for imaging azide-labeled biomolecules via a copper-free "click-through" reaction. Cyanine5 DBCO has no apparent cytotoxicity or animal toxicity and shows no damage to the physiological functions of cells other than the target cells (azide-labeled cells). Cyanine5 DBCO can be used to label and track cells in vitro and in vivo (Ex=635 nm, Em=650-700 nm) .
    Cyanine 5 DBCO
  • HY-P1238
    Neuromedin U, rat

    Neuromedin U (rat); Rat neuromedin U-23

    		 Neuromedin U Receptor (NMUR) Neurological Disease
    Neuromedin U, rat is a 23-amino acid brain-gut peptide. Neuromedin U (NMU), through its cognate receptor NMUR2 in the central nervous system, regulates several important physiological functions, including energy balance, stress response, and nociception.
    Neuromedin U, rat
  • HY-N4298
    Epitheaflagallin 3-O-gallate

    		MMP Metabolic Disease Inflammation/Immunology
    Epitheaflagallin 3-O-gallate is a minor polyphenol in black tea. Epitheaflagallin 3-O-gallate exhibits versatile physiological functions in vivo and in vitro, including antioxidative activity, pancreatic lipase inhibition, Streptococcus sorbinusglycosyltransferase inhibition, and an inhibiting effect on the activity of matrix metalloprotease-1 and -3 and their synthesis by human gingival fibroblasts .
    Epitheaflagallin 3-O-gallate
  • HY-23212A
    2-Amino-1,3-bis(carboxylethoxy)propane hydrochloride

    		Amino Acid Derivatives Cancer
    2-Amino-1,3-bis(carboxylethoxy)propane hydrochloride is a non-protein amino acid, sulfamic acid.2-Amino-1,3-bis(carboxylethoxy)propane hydrochloride contains one amino group and two terminal carboxylic acids.2-Amino-1,3-bis(carboxylethoxy)propane hydrochloride has a variety of physiological functions, including maintaining the stability of cell membranes, regulating cholesterol metabolism, supporting the normal function of the nervous system, participating in collagen synthesis, and anti-oxidation .
    2-Amino-1,3-bis(carboxylethoxy)propane hydrochloride
  • HY-P1803
    Protein Kinase C Peptide Substrate

    PKCε; PRKCE ; Peptide Epsilon

    		 PKC Neurological Disease Inflammation/Immunology Endocrinology
    Protein Kinase C Peptide Substrate is targeted to a specific cellular compartment in a manner dependent on second messengers and on specific adapter proteins in response to extracellular signals that activate G-protein-coupled receptors, tyrosine kinase receptors, or tyrosine kinase-coupled receptors. Protein Kinase C Peptide Substrate then regulates various physiological functions including the activation of nervous, endocrine, exocrine, inflammatory, and immune systems .
    Protein Kinase C Peptide Substrate
  • HY-143865
    S1PR1 agonist 2

    		LPL Receptor Inflammation/Immunology
    S1PR1 agonist 2 is a potent agonist of S1PR1. Sphingosine-1-phosphate (S1P) is a cell membrane-derived lysophospholipid signalling molecule that exerts its physiological functions mainly by stimulating some members of the G protein-coupled receptor family. S1PR1 agonist 2 has the potential for the research of autoimmune diseases (extracted from patent WO2021175225A1, compound 1) .
    S1PR1 agonist 2
  • HY-DY1068
    Cyanine5 DBCO hexafluorophosphate (solution)

    		Fluorescent Dye Others
    Cyanine5 DBCO (DBCO-Cy5) hexafluorophosphate (solution) is a low-toxicity azide reactive probe (NIR fluorescent dye) , for imaging azide-labeled biomolecules via a copper-free "click-through" reaction. Cyanine5 DBCO hexafluorophosphate has no apparent cytotoxicity or animal toxicity and shows no damage to the physiological functions of cells other than the target cells (azide-labeled cells). Cyanine5 DBCO hexafluorophosphate can be used to label and track cells in vitro and in vivo (Ex=635 nm, Em=650-700 nm) .
    Solvent and concentration: DMSO: 10 mM
    Cyanine5 DBCO hexafluorophosphate (solution)
  • HY-B1204S2
    Histamine-13C5, 15N3

    Ergamine-13C5, 15N3

    		 Isotope-Labeled Compounds Histamine Receptor p38 MAPK Akt Reactive Oxygen Species (ROS) Apoptosis Endogenous Metabolite Neurological Disease Inflammation/Immunology Endocrinology Cancer
    Histamine- 13C5, 15N3 (Ergamine- 13C5, 15N3) is the 13C and 15N labeled isotope of Histamine (HY-B1204). Histamine is the agonist for histamine receptor and a vasodilator. Histamine is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma .
    Histamine-13C5, 15N3
  • HY-121650
    ADTN

    		Dopamine Receptor Neurological Disease
    ADTN is a dopamine receptor agonist that has the activity of promoting dopamine neurotransmission. ADTN can be used to increase the release of neurotransmitters, thereby improving dopamine-related physiological functions. ADTN's potential applications include inhibiting mental illness and improving cognitive function .
    ADTN
  • HY-P10687
    H3B10-27(13/17αF)

    		RXFP Receptor Others
    H3B10-27(13/17αF) is an excellent scaffold for further developing reagent candidates and an important tool for understanding the physiological functions of the neuropeptide G protein-coupled receptor RXFP3, and it's very stable in serum .
    H3B10-27(13/17αF)
  • HY-174540
    Human SERPINA1 mRNA

    		mRNA Cancer
    Human SERPINA1 mRNA encodes the human serpin family A member 1 (SERPINA1) protein, a serine protease inhibitor belonging to the serpin superfamily. SERPINA1’s major physiological function is the protection of the lower respiratory tract against proteolytic destruction by human leukocyte elastase (HLE).
    Human SERPINA1 mRNA
  • HY-143864
    S1PR1 agonist 1

    		LPL Receptor Inflammation/Immunology
    S1PR1 agonist 1 is a potent agonist of S1PR1. Sphingosine-1-phosphate (S1P) is a cell membrane-derived lysophospholipid signalling molecule that exerts its physiological functions mainly by stimulating some members of the G protein-coupled receptor family. S1PR1 agonist 1 has the potential for the research of autoimmune diseases (extracted from patent WO2021175223A1, compound 22) .
    S1PR1 agonist 1
  • HY-100481
    RP 72540

    RPR101048

    		 Cholecystokinin Receptor Neurological Disease
    RP 72540 is a selective CCK-B receptor antagonist, with IC50 values of 2.4, 1.2, and 3.8 nM for CCK-B receptors in the guinea pig cerebral cortex, rat cerebral cortex, and mouse brain, respectively. RP 72540 effectively inhibits CCK-8-induced neuronal firing and dose-dependently inhibits gastric acid secretion, making it potentially valuable in studies of acid secretion. RP 72540 is an important tool for investigating the physiological functions of CCK B receptors .
    RP 72540
  • HY-A0129R
    Histamine phosphate (Standard)

    Histamine diphosphate (Standard)

    		 Reference Standards Histamine Receptor p38 MAPK Akt Reactive Oxygen Species (ROS) Apoptosis Endogenous Metabolite Neurological Disease Inflammation/Immunology Endocrinology Cancer
    Histamine phosphate (Standard) is the analytical standard of Histamine phosphate (HY-A0129). This product is intended for research and analytical applications. Histamine phosphate is the agonist for histamine receptor and a vasodilator. Histamine phosphate is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine phosphate affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine phosphate can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma .
    Histamine phosphate (Standard)
  • HY-B1204S4
    Histamine-15N3

    Ergamine-15N3

    		 Isotope-Labeled Compounds Histamine Receptor p38 MAPK Akt Reactive Oxygen Species (ROS) Apoptosis Endogenous Metabolite Neurological Disease Inflammation/Immunology Endocrinology Cancer
    Histamine- 15N3 is the 15N3-labeled Histamine (HY-B1204). Histamine is the agonist for histamine receptor and a vasodilator. Histamine is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma .
    Histamine-15N3
  • HY-114540
    CP-339818

    		Potassium Channel HCN Channel Neurological Disease
    CP-339818 is a non-peptide Kv1.3 channel (IC50 = 200 nM) and Kv1.4 channel blocker. CP 339818 inhibits HCN channel with IC50s of 18.9 μM and 43.4 μM against HCN1 and HCN4 (high Cl -). CP-339818 has significantly weaker blocking effects on Kv1.1, Kv1.2, Kv1.5, Kv1.6, Kv3.1-4, and Kv4.2 channels. CP-339818 selectively blocked Kv1.3, thereby inhibiting the activation process of human T cells. CP-339818 can be used to study the physiological functions of HCN and Kv channels .
    CP-339818
  • HY-13597
    CJ-15161

    		Opioid Receptor Neurological Disease
    CJ-15161 is a κ-opioid receptor agonist. CJ-15161 can be used to study physiological functions such as pain relief and emotional regulation .
    CJ-15161
  • HY-180321
    OAT-1441

    		Glycosidase Others
    OAT-1441 is a selective hAMCase inhibitor with oral activity (IC50 = 7 nM). OAT-1441 can be used to study the physiological functions of hAMC enzymes .
    OAT-1441
  • HY-N17770
    Obtusinaphthalenside B

    		Others Neurological Disease Inflammation/Immunology
    Obtusinaphthalenside B is a novel naphthyl glycoside compound that can be isolated from Cassia obtusifolia seeds. Cassia obtusifolia has physiological functions related to neuroprotection, anti-inflammation, and hepatoprotection.
    Obtusinaphthalenside B
  • HY-N17768
    Obtusichromoneside B

    		Others Neurological Disease Inflammation/Immunology
    Obtusichromoneside B is a novel naphthyl glycoside compound that can be isolated from Cassia obtusifolia seeds. Cassia obtusifolia possesses various physiological functions, including neuroprotection, anti-inflammatory effects, and hepatoprotection.
    Obtusichromoneside B
  • HY-D3207
    DHUCu-1

    		Fluorescent Dye Neurological Disease
    DHUCu-1 is a lysosome-targeted NIR divalent copper ion probe with high water solubility. DHUCu-1 serves as a tool for investigating the physiological functions of Cu 2+ and related diseases, such as Menke syndrome, Wilson's disease, and Alzheimer's disease .
    DHUCu-1
  • HY-21191S
    Perfluorobutanesulfonic acid-13C3 sodium

    PFBS-13C3 sodium

    		 Isotope-Labeled Compounds Biochemical Assay Reagents Parasite Metabolic Disease
    Perfluorobutanesulfonic acid- 13C3 (PFBS- 13C3) sodium is the 13C-labeled Perfluorobutanesulfonic acid (HY-21191). Perfluorobutanesulfonic acid is a surfactant that can disrupt the development of pancreatic organs and lipid metabolism regulation in zebrafish. Perfluorobutanesulfonic acid can harm the reproductive ability of nematodes (Caenorhabditis elegans) and alter the physiological functions of their offspring .
    Perfluorobutanesulfonic acid-13C3 sodium

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: