Search Result
Results for "
respiratory+tract+infections
" in MedChemExpress (MCE) Product Catalog:
6
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-P990774
-
|
ASP-7266; TRAB-1; UPB-101
|
Interleukin Related
|
Inflammation/Immunology
|
|
Verekitug (ASP-7266; TRAB-1; UPB-101) is a human monoclonal antibody targeting the thymic stromal lymphopoietin receptor (TSLPR), with a mean half-life of approximately 20 days. At doses of Verekitug ≥100 mg, complete and sustained TSLPR-specific occupancy is achieved, and the antibody does not bind to IL-7Rα. By inhibiting TSLP-driven inflammatory responses, Verekitug blocks TSLP-induced cell proliferation and TARC expression, while reducing fractional exhaled NO levels, blood eosinophil counts, and levels of IL-5 and IgE. Verekitug significantly improves scores for nasal polyps, nasal congestion and olfactory dysfunction, with favorable safety and good tolerability; potential adverse reactions include headache, upper respiratory tract infection, sinusitis and nasopharyngitis. Verekitug is used in relevant studies on asthma, chronic rhinosinusitis with nasal polyps and chronic obstructive pulmonary disease .
|
-
-
- HY-B0198
-
-
-
- HY-B1156
-
|
Cefradine; SQ-11436
|
Bacterial
Antibiotic
TOPK
|
Infection
Inflammation/Immunology
|
|
Cephradine (Cefradine) is a broad-spectrum and orally active cephalosporin. Cephradine is active against both gram-positive and gram-negative pathogens. Cephradine is effective in eradicating most penicillinase-producing organisms. Cephradine has been used in the research of genitourinary, gastrointestinal and respiratory tract infections, and in infections of the skin and soft tissues. Cephradine blocks solar-ultraviolet induced skin inflammation through direct inhibition of TOPK .
|
-
-
- HY-B1050
-
|
SB-265805S; LB-20304a
|
Bacterial
Antibiotic
DNA/RNA Synthesis
Topoisomerase
|
Infection
|
|
Gemifloxacin mesylate (SB-265805S; LB-20304a) is an orally active broad-spectrum quinolone antibacterial antibiotic. Gemifloxacin mesylate inhibits DNA synthesis by inhibiting DNA gyrase and Topoisomerase IV activities. Gemifloxacin mesylate has potent antibacterial activities against gram-positive bacteria in vitro efficacy study, particularly Streptococci and Staphylococci. Gemifloxacin mesylate has been used in the research of respiratory tract infections .
|
-
-
- HY-B0035
-
|
Sulfadimidine; Sulfadimerazine
|
Bacterial
Antibiotic
|
Infection
|
|
Sulfamethazine (Sulfadimidine) is an antimicrobial agent with blood-brain barrier permeability. Sulfamethazine is widely used to treat and prevent various animal diseases (such as gastrointestinal and respiratory tract infections). In China and the European Commission, the maximum residue level for Sulfamethazine in animal product is set at 100 μg/kg .
|
-
-
- HY-B0395C
-
|
DU6859a hydrate
|
Bacterial
Antibiotic
|
Infection
|
|
Sitafloxacin (DU6859a) hydrate is an orally active fluoroquinolone antibiotic (antibiotic) with in vitro activity against a wide range of Gram-positive and -negative bacteria, including anaerobic bacteria, as well as atypical pathogens. Sitafloxacin is used in the study of respiratory tract infections and urinary tract infections .
|
-
-
- HY-128449
-
|
Cefradine monohydrate
|
Bacterial
Antibiotic
TOPK
|
Infection
Inflammation/Immunology
|
|
Cephradine (Cefradine) monohydrate is a broad-spectrum and orally active cephalosporin. Cephradine monohydrate is active against both grampositive and gram-negative pathogens and effective in eradicating most penicillinase-producing organisms known to be resistant to penicillin G, penicillin V, and ampicillin. Cephradine monohydrate has been used in the research of genitourinary, gastrointestinal and respiratory tract infections, and in infections of the skin and soft tissues. Cephradine monohydrate blocks solar-ultraviolet induced skin inflammation through direct inhibition of TOPK .
|
-
-
- HY-N0677A
-
|
Potassium dehydroandrographolide succinate
|
Antibiotic
|
Infection
Inflammation/Immunology
|
|
Kalii Dehydrographolidi Succinas (Potassium dehydroandrographolide succinate) is an antibiotic. Kalii Dehydrographolidi Succinas exerts immunostimulatory, anti-infective and anti-inflammatory effects . Kalii Dehydrographolidi Succinas shows potential for research on viral pneumonia and viral upper respiratory tract infections .
|
-
-
- HY-B0035A
-
|
Sulfadimidine sodium; Sulfadimerazine sodium
|
Bacterial
Antibiotic
|
Infection
|
|
Sulfamethazine sodium (Sulfadimidine sodium) is an antimicrobial with blood-brain barrier permeability. Sulfamethazine sodium is widely used to treat and prevent various animal diseases (such as gastrointestinal and respiratory tract infections). In China and the European Commission, the maximum residue level for Sulfamethazine sodium in animal product is set at 100 μg/kg .
|
-
-
- HY-B0395
-
|
DU6859a
|
Bacterial
Antibiotic
|
Infection
|
|
Sitafloxacin (DU6859a) is a potent, orally active fluoroquinolone antibiotic. Sitafloxacin shows antichlamydial activity and antibacterial activities against a broad range of gram-positive and gram-negative bacteria, including anaerobic bacteria, as well as against atypical pathogens. Sitafloxacin can be used for the research of respiratory tract infection and urinary tract infection .
|
-
-
- HY-159688
-
|
|
Antibiotic
Bacterial
Penicillin-binding protein (PBP)
Interleukin Related
|
Infection
|
|
Cefditoren is a broad-spectrum oral active cephalosporin that acts as a penicillin-binding protein (PBP) inhibitor. Cefditoren binds to specific PBPs in Gram-positive and Gram-negative bacteria, thereby inhibiting cell wall synthesis. Cefditoren also reduces serum levels of the inflammatory biomarkers IL-6 and KL-6. Cefditoren can be used in research related to acute exacerbation of chronic bronchitis, pharyngitis-tonsillitis, uncomplicated skin and skin structure infections, respiratory tract infections, acute pyelonephritis, and enterococcal endocarditis .
|
-
-
- HY-N0677
-
|
|
Influenza Virus
Prostaglandin Receptor
Akt
GSK-3
|
Infection
Inflammation/Immunology
Cancer
|
|
Dehydroandrographolide succinate can be extracted from herbal medicine Andrographis paniculata (Burm f) Nees, is widely used in research for viral pneumonia and viral upper respiratory tract infections because of its immunostimulatory, anti-infective and anti-inflammatory effect. Dehydroandrographolide succinate exerts antithrombotic effect. Dehydroandrographolide succinate significantly inhibits the platelet aggregation rate (ED50 = 386.9 mg/kg) by decreasing TXB2 levels. Dehydroandrographolide succinate mitigates muscle astrophy via the Akt/GSK3β and MuRF-1 pathways .
|
-
-
- HY-N7101
-
|
U-76,252; CS-807
|
Bacterial
Antibiotic
Penicillin-binding protein (PBP)
|
Infection
|
|
Cefpodoxime Proxetil is an orally active broad spectrum third-generation cephalosporin with potent antibacterial activity against both Gram-positive and Gram-negative bacteria including staphylococci, streptococci, Haemophilus influenzae, Neisseria gonorrhoeae, Escherichia coli, Klebsiella pnuemoniae, Citrobacter spp, and Proteus spp. Cefpodoxime Proxetil binds to penicillin binding proteins (PBPs), which inhibits peptidoglycan synthesis, finally results in interfering bacterial cell wall biosynthesis. Cefpodoxime Proxetil can be used against skin structure infections, acute otitis media, pharyngitis, tonsillitis, upper respiratory tract infection, urinary tract infections and sexually transmitted diseases .
|
-
-
- HY-A0161A
-
|
Clofedanol hydrochloride; Calmotusin hydrochloride; NSC 113595 hydrochloride
|
Others
|
Infection
|
|
Chlophedianol (Clofedanol) hydrochloride is an orally active and potent antitussive agent. Chlophedianol hydrochloride can be used for the research of acute cough due to upper respiratory tract infections (URIs) .
|
-
-
- HY-16745
-
|
KRP-AM1977
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
|
Lascufloxacin (KRP-AM1977X) is a potent and orally active fluoroquinolone antibacterial agent. Lascufloxacin potently inhibits infections caused by various pathogens, including quinolone-resistant strains. Lascufloxacin has the potential for various infectious diseases treatment, including lower respiratory tract infections .
|
-
-
- HY-D0184R
-
|
Deoxycytidine (Standard); Cytosine deoxyriboside (Standard); Deoxyribose cytidine (Standard)
|
Reference Standards
Endogenous Metabolite
|
Cancer
|
|
Cefaclor (monohydrate) (Standard) is the analytical standard of Cefaclor (monohydrate). This product is intended for research and analytical applications. Cefaclor is a well-absorbed orally active cephalosporin antibiotic. Cefaclor can specifically bind to specific for penicillin-binding protein 3 (PBP3). Cefaclor can be used for the research of depression and kinds of infections caused by bacteria, such as respiratory tract infections, bacterial bronchitis, pharyngitis and skin infections .
|
-
-
- HY-B0035S
-
|
Sulfadimidine-d4; Sulfadimerazine-d4
|
Bacterial
|
Infection
|
|
Sulfamethazine-d4 (Sulfadimidine-d4) is a deuterium labeled Sulfamethazine (Sulfadimidine). Sulfamethazine is an antimicrobial that is widely used to treat and prevent various animal diseases (such as gastrointestinal and respiratory tract infections) .
|
-
-
- HY-B0035S2
-
|
Sulfadimidine-13C6; Sulfadimerazine-13C6
|
Antibiotic
Bacterial
Isotope-Labeled Compounds
|
Others
|
|
Sulfamethazine- 13C6 is a 13C-labeled Sulfamethazine (HY-A0178). Sulfamethazine (Sulfadimidine) is an antimicrobial that is widely used to treat and prevent various animal diseases (such as gastrointestinal and respiratory tract infections) .
|
-
-
- HY-132282
-
|
|
Bacterial
|
Infection
|
|
Thiamphenicol glycinate hydrochloride is a broad-spectrum antibacterial agent that can be used for respiratory tract infections research .
|
-
-
- HY-B0198A
-
-
-
- HY-108971
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Demecycline, a tetracycline antibiotic, is the C6-demethylated derivative of Tetracycline (HY-A0107) against bacterial infections including pneumonia and other respiratory tract infections .
|
-
-
- HY-107798
-
|
|
Bacterial
|
Infection
|
|
Potassium guaiacolsulfonate hemihydrate is an orally active expectorant used for acute respiratory tract infections. Potassium guaiacolsulfonate hemihydrate helps loosen mucus and used for a cough caused by the common cold, infections or allergies in combination with other agents .
|
-
-
- HY-B0035R
-
|
Sulfadimidine (Standard); Sulfadimerazine (Standard)
|
Reference Standards
Bacterial
Antibiotic
|
Infection
|
|
Sulfamethazine (Standard) is the analytical standard of Sulfamethazine. This product is intended for research and analytical applications. Sulfamethazine (Sulfadimidine) is an antimicrobial that is widely used to treat and prevent various animal diseases (such as gastrointestinal and respiratory tract infections). In China and the European Commission, the maximum residue level for Sulfamethazine in animal product is set at 100 μg/kg .
|
-
-
- HY-B0395CR
-
|
DU6859a hydrate (Standard)
|
Bacterial
Antibiotic
Reference Standards
|
Infection
|
|
Sitafloxacin (hydrate) (Standard) is the analytical standard of Sitafloxacin (hydrate). This product is intended for research and analytical applications. Sitafloxacin (DU6859a) hydrate is an orally active fluoroquinolone antibiotic (antibiotic) with in vitro activity against a wide range of Gram-positive and -negative bacteria, including anaerobic bacteria, as well as atypical pathogens. Sitafloxacin is used in the study of respiratory tract infections and urinary tract infections .
|
-
-
- HY-139805
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Ticarcillin is a semisynthetic, extended-spectrum, carboxypenicillin antibacterial agent, and is active against gram-positive cocci, including streptococci and staphylococci. Ticarcillin is also effective against most gram-negative organisms, including Pseudomonas aeruginosa. Ticarcillin can be used in lower respiratory tract infections, skin and skin structure infections, urinary tract infections, and intraabdominal infections research .
|
-
-
- HY-A0035
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Faropenem is a potent and orally active beta-lactam antibiotic. Faropenem demonstrates broad-spectrum in vitro antimicrobial activity against many gram-positive and -negative aerobes and anaerobes. Faropenem is resistant to hydrolysis by nearly all beta-lactamases, including extended-spectrum beta-lactamases and AmpC beta-lactamases. Faropenem is developed as an oral proagent, faropenem medoxomil, for the research of respiratory tract infections .
|
-
-
- HY-163773
-
|
|
RSV
|
Infection
|
|
JNJ-7950 (compound 5c) exhibits antiviral activity against RSV with an EC50 value of 0.78 nM. JNJ-7950 can be used in the study of respiratory tract infections .
|
-
-
- HY-B0455B
-
|
SC47111A (aspartate); NY-198 (aspartate)
|
Bacterial
Antibiotic
|
Infection
|
|
Lomefloxacin (SC47111A) aspartate is a broad-spectrum quinolone antibiotic, with antimicrobial activity. Lomefloxacin aspartate can be used for researching respiratory tract infections, genitourinary infections, gastrointestinal infections, ENT infections, etc. .
|
-
-
- HY-B0395A
-
|
DU6859a hydrochloride
|
Antibiotic
Bacterial
|
Infection
|
|
Sitafloxacin (DU6859a) hydrochloride is a potent, orally active fluoroquinolone antibiotic. Sitafloxacin hydrochloride shows antichlamydial activity and antibacterial activities against a broad range of gram-positive and gram-negative bacteria, including anaerobic bacteria, as well as against atypical pathogens. Sitafloxacin hydrochloride can be used for the research of respiratory tract infection and urinary tract infection .
|
-
-
- HY-A0161
-
|
Clofedanol; Calmotusin; NSC 113595
|
Others
|
Infection
|
|
Chlophedianol (Clofedanol) is an orally active and potent antitussive agent. Chlophedianol can be used for the research of acute cough due to upper respiratory tract infections (URIs) .
|
-
-
- HY-P991498
-
|
|
Influenza Virus
|
Infection
|
|
CAL-203 is a human monoclonal antibody (mAb) targeting F, Fusion glycoprotein F0. CAL-203 can be used in respiratory tract infections research.
|
-
-
- HY-B0455S
-
|
SC47111A-d5 hydrochloride; NY-198-d5 hydrochloride
|
Isotope-Labeled Compounds
|
Inflammation/Immunology
|
|
Lomefloxacin-d5 (hydrochloride) is the deuterium labeled Lomefloxacin hydrochloride. Lomefloxacin (SC47111A) hydrochloride is a broad-spectrum quinolone antibiotic, with antimicrobial activity. Lomefloxacin hydrochloride is used for the research of respiratory tract infections, genitourinary infections, gastrointestinal infections, ENT infections, etc. .
|
-
-
- HY-A0161AR
-
|
Clofedanol hydrochloride (Standard); Calmotusin hydrochloride (Standard); NSC 113595 hydrochloride (Standard)
|
Sigma Receptor
Reference Standards
|
Infection
|
|
Chlophedianol (hydrochloride) (Standard) is the analytical standard of Chlophedianol (hydrochloride). This product is intended for research and analytical applications. Chlophedianol (Clofedanol) hydrochloride is an orally active and potent antitussive agent. Chlophedianol hydrochloride can be used for the research of acute cough due to upper respiratory tract infections (URIs) .
|
-
-
- HY-A0161S
-
|
Clofedanol-13C6; Calmotusin-13C6; NSC 113595-13C6
|
Isotope-Labeled Compounds
|
Infection
|
|
Chlophedianol- 13C6 is the 13C labeled Chlophedianol (HY-A0161). Chlophedianol is an orally active and potent antitussive agent. Chlophedianol can be used for the research of acute cough due to upper respiratory tract infections (URIs) .
|
-
-
- HY-B0455AR
-
|
SC47111A (Standard); NY-198 (Standard)
|
Reference Standards
Bacterial
Antibiotic
|
Infection
|
|
Lomefloxacin (Standard) is the analytical standard of Lomefloxacin. This product is intended for research and analytical applications. Lomefloxacin (SC47111A) is a broad-spectrum quinolone antibiotic, with antimicrobial activity. Lomefloxacin is used for the research of respiratory tract infections, genitourinary infections, gastrointestinal infections, ENT infections, etc. .
|
-
-
- HY-B1908R
-
|
SF-837 (Standard); Antibiotic SF-837 (Standard)
|
Reference Standards
Bacterial
Antibiotic
|
Infection
|
|
Lomefloxacin (Standard) is the analytical standard of Lomefloxacin. This product is intended for research and analytical applications. Lomefloxacin (SC47111A) is a broad-spectrum quinolone antibiotic, with antimicrobial activity. Lomefloxacin is used for the research of respiratory tract infections, genitourinary infections, gastrointestinal infections, ENT infections, etc. .
|
-
-
- HY-107798R
-
|
|
Reference Standards
Bacterial
|
Infection
|
|
Potassium guaiacolsulfonate (hemihydrate) (Standard) is the analytical standard of Potassium guaiacolsulfonate (hemihydrate). This product is intended for research and analytical applications. Potassium guaiacolsulfonate hemihydrate is an orally active expectorant used for acute respiratory tract infections. Potassium guaiacolsulfonate hemihydrate helps loosen mucus and used for a cough caused by the common cold, infections or allergies in combination with other agents .
|
-
-
- HY-B0035AR
-
|
Sulfadimidine sodium (Standard); Sulfadimerazine sodium (Standard)
|
Reference Standards
Bacterial
Antibiotic
|
Infection
|
|
Sulfamethazine (sodium) (Standard) is the analytical standard of Sulfamethazine (sodium). This product is intended for research and analytical applications. Sulfamethazine sodium (Sulfadimidine sodium) is an antimicrobial that is widely used to treat and prevent various animal diseases (such as gastrointestinal and respiratory tract infections). In China and the European Commission, the maximum residue level for Sulfamethazine sodium in animal product is set at 100 μg/kg[1][2].
|
-
-
- HY-B0395B
-
|
DU6859a monohydrate
|
Bacterial
Antibiotic
|
Infection
|
|
Sitafloxacin (DU6859a) monohydrate is a potent, orally active fluoroquinolone antibiotic. Sitafloxacin monohydrate shows antichlamydial activity and antibacterial activities against a broad range of gram-positive and gram-negative bacteria, including anaerobic bacteria, as well as against atypical pathogens. Sitafloxacin monohydrate can be used for the research of respiratory tract infection and urinary tract infection .
|
-
-
- HY-B0220H
-
|
|
DNA/RNA Synthesis
Bacterial
Antibiotic
|
Infection
|
|
Erythromycin hydrochloride is a protein synthesis inhibitor with activity against the growth of both Gram-negative and Gram-positive bacteria. Erythromycin hydrochloride is commonly used in biomedicine to inhibit diseases caused by bacterial infections. Erythromycin hydrochloride is also involved in the inhibition of mammalian mRNA splicing. The application range of erythromycin hydrochloride includes respiratory tract infections, skin infections, and other infections caused by sensitive bacteria .
|
-
-
- HY-B0198R
-
-
-
- HY-139805A
-
|
|
Bacterial
Antibiotic
|
Cancer
|
|
Ticarcillin monosodium is a semisynthetic, extended-spectrum, carboxypenicillin antibacterial agent, and is active against gram-positive cocci, including streptococci and staphylococci. Ticarcillin monosodium is also effective against most gram-negative organisms, including Pseudomonas aeruginosa. Ticarcillin monosodium can be used in lower respiratory tract infections, skin and skin structure infections, urinary tract infections, and intraabdominal infections research .
|
-
-
- HY-B0198AR
-
-
-
- HY-B1156A
-
|
Cefradine sodium; SQ-11436 sodium
|
Bacterial
Antibiotic
TOPK
|
Infection
Inflammation/Immunology
|
|
Cephradine sodium is a broad-spectrum and orally active cephalosporin. Cephradine sodium is active against both gram-positive and gram-negative pathogens. Cephradine sodium is effective in eradicating most penicillinase-producing organisms. Cephradine sodium has been used in the research of genitourinary, gastrointestinal and respiratory tract infections, and in infections of the skin and soft tissues. Cephradine sodium blocks solar-ultraviolet induced skin inflammation through direct inhibition of TOPK .
|
-
-
- HY-111047
-
|
|
Topoisomerase
Bacterial
|
Infection
|
|
GSK945237 is a potent and orally active bacterial type IIA topoisomerases inhibitor. GSK945237 shows broad-spectrum activity against Gram-positive and Gram-negative bacteria (IC50 of 0.034 μg/mL against H. influenzae DNA gyrase). GSK945237 demonstrates good in vivo efficacy in a rat respiratory tract infection model. GSK945237 can be used for anti-infection research .
|
-
-
- HY-B0395S
-
|
DU6859a-d4
|
Isotope-Labeled Compounds
Bacterial
Antibiotic
|
Infection
|
|
Sitafloxacin-d4 (DU6859a-d4) is deuterium labeled Sitafloxacin. Sitafloxacin (DU6859a) is a potent, orally active fluoroquinolone antibiotic. Sitafloxacin shows antichlamydial activity and antibacterial activities against a broad range of gram-positive and gram-negative bacteria, including anaerobic bacteria, as well as against atypical pathogens. Sitafloxacin can be used for the research of respiratory tract infection and urinary tract infection .
|
-
-
- HY-B1050R
-
|
SB-265805S (Standard); LB-20304a (Standard)
|
Reference Standards
Bacterial
Antibiotic
DNA/RNA Synthesis
Topoisomerase
|
Infection
|
|
Gemifloxacin (mesylate) (Standard) is the analytical standard of Gemifloxacin (mesylate). This product is intended for research and analytical applications. Gemifloxacin mesylate (SB-265805S; LB-20304a) is an orally active broad-spectrum quinolone antibacterial antibiotic. Gemifloxacin mesylate inhibits DNA synthesis by inhibiting DNA gyrase and Topoisomerase IV activities. Gemifloxacin mesylate has potent antibacterial activities against gram-positive bacteria in vitro efficacy study, particularly Streptococci and Staphylococci. Gemifloxacin mesylate has been used in the research of respiratory tract infections .
|
-
-
- HY-B1156R
-
|
Cefradine (Standard); SQ-11436 (Standard)
|
Reference Standards
Bacterial
Antibiotic
TOPK
|
Infection
Inflammation/Immunology
|
|
Cephradine (Standard) is the analytical standard of Cephradine. This product is intended for research and analytical applications. Cephradine (Cefradine) is a broad-spectrum and orally active cephalosporin. Cephradine is active against both gram-positive and gram-negative pathogens. Cephradine is effective in eradicating most penicillinase-producing organisms. Cephradine has been used in the research of genitourinary, gastrointestinal and respiratory tract infections, and in infections of the skin and soft tissues. Cephradine blocks solar-ultraviolet induced skin inflammation through direct inhibition of TOPK .
|
-
-
- HY-N7101R
-
|
U-76,252 (Standard); CS-807 (Standard)
|
Reference Standards
Bacterial
Antibiotic
Penicillin-binding protein (PBP)
|
Infection
|
|
Cefpodoxime Proxetil (Standard) is the analytical standard of Cefpodoxime Proxetil. This product is intended for research and analytical applications. Cefpodoxime Proxetil is an orally active broad spectrum third-generation cephalosporin with potent antibacterial activity against both Gram-positive and Gram-negative bacteria including staphylococci, streptococci, Haemophilus influenzae, Neisseria gonorrhoeae, Escherichia coli, Klebsiella pnuemoniae, Citrobacter spp, and Proteus spp. Cefpodoxime Proxetil binds to penicillin binding proteins (PBPs), which inhibits peptidoglycan synthesis, finally results in interfering bacterial cell wall biosynthesis. Cefpodoxime Proxetil can be used against skin structure infections, acute otitis media, pharyngitis, tonsillitis, upper respiratory tract infection, urinary tract infections and sexually transmitted diseases .
|
-
-
- HY-N7101S
-
|
U-76-d7,252-d7; CS-807-d7
|
Isotope-Labeled Compounds
Bacterial
Antibiotic
Penicillin-binding protein (PBP)
|
Infection
|
|
Cefpodoxime proxetil-d7 (U-76-d7,252-d7; CS-807-d7) is the deuterium labeled Cefpodoxime Proxetil (HY-N7101). Cefpodoxime Proxetil is an orally active broad spectrum third-generation cephalosporin with potent antibacterial activity against both Gram-positive and Gram-negative bacteria including staphylococci, streptococci, Haemophilus influenzae, Neisseria gonorrhoeae, Escherichia coli, Klebsiella pnuemoniae, Citrobacter spp, and Proteus spp. Cefpodoxime Proxetil binds to penicillin binding proteins (PBPs), which inhibits peptidoglycan synthesis, finally results in interfering bacterial cell wall biosynthesis. Cefpodoxime Proxetil can be used against skin structure infections, acute otitis media, pharyngitis, tonsillitis, upper respiratory tract infection, urinary tract infections and sexually transmitted diseases .
|
-
| Cat. No. |
Product Name |
Target |
Research Area |
Image |
-
- HY-P990774
-
|
ASP-7266; TRAB-1; UPB-101
|
Interleukin Related
|
Inflammation/Immunology
|
|
Verekitug (ASP-7266; TRAB-1; UPB-101) is a human monoclonal antibody targeting the thymic stromal lymphopoietin receptor (TSLPR), with a mean half-life of approximately 20 days. At doses of Verekitug ≥100 mg, complete and sustained TSLPR-specific occupancy is achieved, and the antibody does not bind to IL-7Rα. By inhibiting TSLP-driven inflammatory responses, Verekitug blocks TSLP-induced cell proliferation and TARC expression, while reducing fractional exhaled NO levels, blood eosinophil counts, and levels of IL-5 and IgE. Verekitug significantly improves scores for nasal polyps, nasal congestion and olfactory dysfunction, with favorable safety and good tolerability; potential adverse reactions include headache, upper respiratory tract infection, sinusitis and nasopharyngitis. Verekitug is used in relevant studies on asthma, chronic rhinosinusitis with nasal polyps and chronic obstructive pulmonary disease .
|
-
(5)
-
- HY-P991498
-
|
|
Influenza Virus
|
Infection
|
|
CAL-203 is a human monoclonal antibody (mAb) targeting F, Fusion glycoprotein F0. CAL-203 can be used in respiratory tract infections research.
|
-
(5)
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-B0035S
-
|
|
|
Sulfamethazine-d4 (Sulfadimidine-d4) is a deuterium labeled Sulfamethazine (Sulfadimidine). Sulfamethazine is an antimicrobial that is widely used to treat and prevent various animal diseases (such as gastrointestinal and respiratory tract infections) .
|
-
-
- HY-B0035S2
-
|
|
|
Sulfamethazine- 13C6 is a 13C-labeled Sulfamethazine (HY-A0178). Sulfamethazine (Sulfadimidine) is an antimicrobial that is widely used to treat and prevent various animal diseases (such as gastrointestinal and respiratory tract infections) .
|
-
-
- HY-B0455S
-
|
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Lomefloxacin-d5 (hydrochloride) is the deuterium labeled Lomefloxacin hydrochloride. Lomefloxacin (SC47111A) hydrochloride is a broad-spectrum quinolone antibiotic, with antimicrobial activity. Lomefloxacin hydrochloride is used for the research of respiratory tract infections, genitourinary infections, gastrointestinal infections, ENT infections, etc. .
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- HY-A0161S
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Chlophedianol- 13C6 is the 13C labeled Chlophedianol (HY-A0161). Chlophedianol is an orally active and potent antitussive agent. Chlophedianol can be used for the research of acute cough due to upper respiratory tract infections (URIs) .
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- HY-B0395S
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Sitafloxacin-d4 (DU6859a-d4) is deuterium labeled Sitafloxacin. Sitafloxacin (DU6859a) is a potent, orally active fluoroquinolone antibiotic. Sitafloxacin shows antichlamydial activity and antibacterial activities against a broad range of gram-positive and gram-negative bacteria, including anaerobic bacteria, as well as against atypical pathogens. Sitafloxacin can be used for the research of respiratory tract infection and urinary tract infection .
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- HY-N7101S
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Cefpodoxime proxetil-d7 (U-76-d7,252-d7; CS-807-d7) is the deuterium labeled Cefpodoxime Proxetil (HY-N7101). Cefpodoxime Proxetil is an orally active broad spectrum third-generation cephalosporin with potent antibacterial activity against both Gram-positive and Gram-negative bacteria including staphylococci, streptococci, Haemophilus influenzae, Neisseria gonorrhoeae, Escherichia coli, Klebsiella pnuemoniae, Citrobacter spp, and Proteus spp. Cefpodoxime Proxetil binds to penicillin binding proteins (PBPs), which inhibits peptidoglycan synthesis, finally results in interfering bacterial cell wall biosynthesis. Cefpodoxime Proxetil can be used against skin structure infections, acute otitis media, pharyngitis, tonsillitis, upper respiratory tract infection, urinary tract infections and sexually transmitted diseases .
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