2. Anti-infection
  3. Antibiotic Bacterial
  4. Ticarcillin

Ticarcillin is a semisynthetic, extended-spectrum, carboxypenicillin antibacterial agent, and is active against gram-positive cocci, including streptococci and staphylococci. Ticarcillin is also effective against most gram-negative organisms, including Pseudomonas aeruginosa. Ticarcillin can be used in lower respiratory tract infections, skin and skin structure infections, urinary tract infections, and intraabdominal infections research.

For research use only. We do not sell to patients.

Ticarcillin Chemical Structure

Ticarcillin Chemical Structure

CAS No. : 34787-01-4

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Other Forms of Ticarcillin:

Ticarcillin Related Antibodies

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Description

Ticarcillin is a semisynthetic, extended-spectrum, carboxypenicillin antibacterial agent, and is active against gram-positive cocci, including streptococci and staphylococci. Ticarcillin is also effective against most gram-negative organisms, including Pseudomonas aeruginosa. Ticarcillin can be used in lower respiratory tract infections, skin and skin structure infections, urinary tract infections, and intraabdominal infections research[1][2][3].

IC50 & Target

β-lactam

 

In Vitro

Ticarcillin treatment (10 mg/L; 18 h) shows antibacterial activities[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Ticarcillin Related Antibodies

Cell Viability Assay[2]

Cell Line: Ps. aeruginosa
Concentration: 10 mg/L
Incubation Time: 18 hours
Result: Showed the MIC for Ticarcillin against strain between 6.3-12.5 mg/L.
In Vivo

Ticarcillin (Subcutaneous injection; 50, 100, 200 mg/kg; once) treatment shows a dose-dependent antibacterial effect[2].
Ticarcillin (Subcutaneous injection; 50, 100, 200 mg/kg; once) treatment shows excellent pharmacokinetic assessment[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Swiss type male mice injected with Ps. aeruginosa[2]
Dosage: 50, 100, 200 mg/kg
Administration: Subcutaneous injection; 50, 100, 200 mg/kg; once
Result: Increased effect significantly (0.001 < P < 0.0025) with increasing dose.
Animal Model: Swiss type male mice injected with Ps. aeruginosa[2]
Dosage: 50, 100, 200 mg/kg
Administration: Subcutaneous injection; 50, 100, 200 mg/kg; once
Result:
Dose (mg/kg) AUCa (mg/kg) Kelb (h-1) T1/2 (min)
Ticarcillin 50 8.76 (0.72) 1.57 (0.18) 26
100 26.14 (0.60) 1.53 (0.11) 27
200 54.56 (2.90) 1.47 (0.12) 28
Molecular Weight

384.43

Formula

C15H16N2O6S2
CAS No.
SMILES

OC([C@H](C1=CSC=C1)C(N[C@H]2[C@]3([H])N(C2=O)[C@H](C(C)(S3)C)C(O)=O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Ticarcillin Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ticarcillin34787-01-4AntibioticBacterialantibacterial agentgram-negative bacteriaATCC 27853Ps. aeruginosaInhibitorinhibitorinhibit

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