Cefpodoxime Proxetil (Standard)
Cefpodoxime Proxetil (Standard) is the analytical standard of Cefpodoxime Proxetil. This product is intended for research and analytical applications. Cefpodoxime Proxetil is an orally active broad spectrum third-generation cephalosporin with potent antibacterial activity against both Gram-positive and Gram-negative bacteria including staphylococci, streptococci, Haemophilus influenzae, Neisseria gonorrhoeae, Escherichia coli, Klebsiella pnuemoniae, Citrobacter spp, and Proteus spp. Cefpodoxime Proxetil binds to penicillin binding proteins (PBPs), which inhibits peptidoglycan synthesis, finally results in interfering bacterial cell wall biosynthesis. Cefpodoxime Proxetil can be used against skin structure infections, acute otitis media, pharyngitis, tonsillitis, upper respiratory tract infection, urinary tract infections and sexually transmitted diseases.
For research use only. We do not sell to patients.
- CAS No.: 87239-81-4
- Formula: C21H27N5O9S2
- Molecular Weight:557.60
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 87239-81-4
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Molecular Weight 557.60
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Formula C21H27N5O9S2
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SMILES
O=C(C(N12)=C(COC)CS[C@]2([H])[C@H](NC(/C(C3=CSC(N)=N3)=N\OC)=O)C1=O)OC(OC(OC(C)C)=O)C
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Synonyms
U-76,252 (Standard); CS-807 (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Todd W. M. (1994). Cefpodoxime proxetil: a comprehensive review. International journal of antimicrobial agents, 4(1), 37–62. [Content Brief]
[2]. Date, A. A., & Nagarsenker, M. S. (2007). Design and evaluation of self-nanoemulsifying drug delivery systems (SNEDDS) for cefpodoxime proxetil. International journal of pharmaceutics, 329(1-2), 166–172. [Content Brief]
[3]. Borin M. T. (1991). A review of the pharmacokinetics of cefpodoxime proxetil. Drugs, 42 Suppl 3, 13–21. [Content Brief]
[4]. Frampton, J. E., et al., (1992). Cefpodoxime proxetil. A review of its antibacterial activity, pharmacokinetic properties and therapeutic potential. Drugs, 44(5), 889–917. [Content Brief]
[6]. Utsui, Y., et al., (1987). In vitro and in vivo antibacterial activities of CS-807, a new oral cephalosporin. Antimicrobial agents and chemotherapy, 31(7), 1085–1092. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)