Otitis Media

Otitis media is an inflammation of the middle ear, commonly presenting with symptoms such as earache, fever, hearing impairment, and vertigo. It encompasses a group of inflammatory conditions, with acute otitis media being a prominent form marked by sudden onset and severe ear pain. In young children, signs may include ear pulling, increased irritability, disrupted sleep, reduced appetite, and fever.
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β-N-Acetylhexosaminidase, Streptococcus pneumoniae
β-N-Acetylhexosaminidase, Streptococcus pneumoniae
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Cat. No.: HY-P2866
CAS No.: 9012-33-3

β-N-Acetylhexosaminidase, Streptococcus pneumoniae is a cell surface virulence factor of Streptococcus pneumoniae, which contains two synergistically acting GH20 domains (with higher activity in GH20-2). β-N-Acetylhexosaminidase, Streptococcus pneumoniae specifically recognizes and hydrolyzes substrates with β(1,2) glycosidic bonds via Trp-443 and Tyr-482 residues. β-N-Acetylhexosaminidase, Streptococcus pneumoniae catalyzes the hydrolysis of β(1,2)-linked N-acetylglucosamine groups and related disaccharides, and promotes persistent colonization of bacteria in the airway by modifying host defense molecules and releasing monosaccharides for bacterial growth. β-N-Acetylhexosaminidase, Streptococcus pneumoniae can be used in studies related to Streptococcus pneumoniae infection, acute pneumonia, otitis media and meningitis.

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