1. Anti-infection
  2. Bacterial Antibiotic
  3. Tazobactam sodium

Tazobactam sodium is an antibiotic of the beta-lactamase inhibitor class. Ceftolozane combines with Tazobactam, extends the activity of ceftolozane against many ESBL-producing Enterobacteriaceae and some Bacteroides spp..

For research use only. We do not sell to patients.

Tazobactam sodium Chemical Structure

Tazobactam sodium Chemical Structure

CAS No. : 89785-84-2

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Based on 6 publication(s) in Google Scholar

Other Forms of Tazobactam sodium:

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Description

Tazobactam sodium is an antibiotic of the beta-lactamase inhibitor class. Ceftolozane combines with Tazobactam, extends the activity of ceftolozane against many ESBL-producing Enterobacteriaceae and some Bacteroides spp..

IC50 & Target

β-lactam

 

Clinical Trial
Molecular Weight

322.27

Formula

C10H11N4NaO5S

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@]([C@@H](N1[C@@]2([H])CC1=O)C(O[Na])=O)([S]2(=O)=O)CN3C=CN=N3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 250 mg/mL (775.75 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1030 mL 15.5149 mL 31.0299 mL
5 mM 0.6206 mL 3.1030 mL 6.2060 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 3.1030 mL 15.5149 mL 31.0299 mL 77.5747 mL
5 mM 0.6206 mL 3.1030 mL 6.2060 mL 15.5149 mL
10 mM 0.3103 mL 1.5515 mL 3.1030 mL 7.7575 mL
15 mM 0.2069 mL 1.0343 mL 2.0687 mL 5.1716 mL
20 mM 0.1551 mL 0.7757 mL 1.5515 mL 3.8787 mL
25 mM 0.1241 mL 0.6206 mL 1.2412 mL 3.1030 mL
30 mM 0.1034 mL 0.5172 mL 1.0343 mL 2.5858 mL
40 mM 0.0776 mL 0.3879 mL 0.7757 mL 1.9394 mL
50 mM 0.0621 mL 0.3103 mL 0.6206 mL 1.5515 mL
60 mM 0.0517 mL 0.2586 mL 0.5172 mL 1.2929 mL
80 mM 0.0388 mL 0.1939 mL 0.3879 mL 0.9697 mL
100 mM 0.0310 mL 0.1551 mL 0.3103 mL 0.7757 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Tazobactam sodium Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Tazobactam sodium
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