1. Anti-infection
  2. Bacterial
  3. Tazobactam

Tazobactam (Synonyms: CL-298741; YTR-830H)

Cat. No.: HY-B1418 Purity: >98.0%
Handling Instructions

Tazobactam is a beta Lactamase Inhibitor with antibacterial activity Target: Antibacterial Tazobactam is a pharmaceutical drug that inhibits the action of bacterial β-lactamases, especially those belonging to the SHV-1 and TEM groups.

For research use only. We do not sell to patients.

Tazobactam Chemical Structure

Tazobactam Chemical Structure

CAS No. : 89786-04-9

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
100 mg USD 50 In-stock
Estimated Time of Arrival: December 31
200 mg USD 70 In-stock
Estimated Time of Arrival: December 31
500 mg USD 90 In-stock
Estimated Time of Arrival: December 31
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Description

Tazobactam is a beta Lactamase Inhibitor with antibacterial activity Target: Antibacterial Tazobactam is a pharmaceutical drug that inhibits the action of bacterial β-lactamases, especially those belonging to the SHV-1 and TEM groups. It is commonly used as its sodium salt, Tazobactam sodium.Tazobactam is combined with the extended spectrum β-lactam antibiotic piperacillin in the drug piperacillin/Tazobactam, one of the preferred antibiotic treatments for nosocomial pneumonia caused by Pseudomonas aeruginosa. Tazobactam broadens the spectrum of piperacillin by making it effective against organisms that express β-lactamase and would normally degrade piperacillin. Tazobactam is derived from the penicillin nucleus and is a penicillinic acid sulfone.

Clinical Trial
Molecular Weight

300.29

Formula

C₁₀H₁₂N₄O₅S

CAS No.

89786-04-9

SMILES

O=C([[email protected]@H]([[email protected]@](CN1N=NC=C1)(C)S([[email protected]]2([H])C3)(=O)=O)N2C3=O)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (166.51 mM; Need ultrasonic)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3301 mL 16.6506 mL 33.3011 mL
5 mM 0.6660 mL 3.3301 mL 6.6602 mL
10 mM 0.3330 mL 1.6651 mL 3.3301 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (8.33 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (8.33 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (8.33 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: >98.0%

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Tazobactam
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HY-B1418
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