1. Anti-infection
    Cell Cycle/DNA Damage
  2. Bacterial
    TOPK
    Antibiotic
  3. Cephradine

Cephradine (Synonyms: Cefradine; SQ-11436)

Cat. No.: HY-B1156 Purity: 95.11%
Handling Instructions

Cephradine (Cefradine) is the first-generation broad-spectrum cephalosporin antibiotic, which also acts as an inhibitor of TOPK (T-LAK cell-originated protein kinase) and suppresses skin inflammation induced by excessive solar ultraviolet.

For research use only. We do not sell to patients.

Cephradine Chemical Structure

Cephradine Chemical Structure

CAS No. : 38821-53-3

Size Price Stock Quantity
Solution
10 mM * 1 mL in DMSO USD 79 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 79 In-stock
Estimated Time of Arrival: December 31
Solid
100 mg USD 72 In-stock
Estimated Time of Arrival: December 31
500 mg USD 132 In-stock
Estimated Time of Arrival: December 31
1 g   Get quote  
5 g   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Cephradine (Cefradine) is the first-generation broad-spectrum cephalosporin antibiotic, which also acts as an inhibitor of TOPK (T-LAK cell-originated protein kinase) and suppresses skin inflammation induced by excessive solar ultraviolet[1].

Clinical Trial
Molecular Weight

349.40

Formula

C₁₆H₁₉N₃O₄S

CAS No.
SMILES

O=C(C(N12)=C(C)CS[[email protected]]2([H])[[email protected]](NC([[email protected]](N)C3=CCC=CC3)=O)C1=O)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 8.33 mg/mL (23.84 mM; Need ultrasonic)

DMSO : ≥ 3.6 mg/mL (10.30 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8620 mL 14.3102 mL 28.6205 mL
5 mM 0.5724 mL 2.8620 mL 5.7241 mL
10 mM 0.2862 mL 1.4310 mL 2.8620 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Keywords:

CephradineCefradine SQ-11436SQ11436SQ 11436SQ-11436BacterialTOPKAntibioticT-LAK cell-originated protein kinaseInhibitorinhibitorinhibit

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Cephradine
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HY-B1156
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