JNJ-7950
Based on 1 Customer Validation
JNJ-7950 (compound 5c) exhibits antiviral activity against RSV with an EC50 value of 0.78 nM. JNJ-7950 can be used in the study of respiratory tract infections.
For research use only. We do not sell to patients.
- Purity : 99.88%
- CAS No.: 3051902-04-3
- Formula: C23H22ClF3N4O3S
- Molecular Weight:526.96
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Protocols
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Description
Chemical Information
-
CAS No. 3051902-04-3
-
Appearance Solid
-
Molecular Weight 526.96
-
Formula C23H22ClF3N4O3S
-
Color White to off-white
-
SMILES
ClC1=CC=C2N(C(CN3C4=C(C5(C3=O)CN(C5)S(C)(=O)=O)C=CC=C4)=NC2=C1)CCCC(F)(F)F
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 27.78 mg/mL (52.72 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Protocols
-
Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
Purity & Documentation
-
Data Sheet (273 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8977 mL | 9.4884 mL | 18.9768 mL | 47.4419 mL |
| 5 mM | 0.3795 mL | 1.8977 mL | 3.7954 mL | 9.4884 mL | |
| 10 mM | 0.1898 mL | 0.9488 mL | 1.8977 mL | 4.7442 mL | |
| 15 mM | 0.1265 mL | 0.6326 mL | 1.2651 mL | 3.1628 mL | |
| 20 mM | 0.0949 mL | 0.4744 mL | 0.9488 mL | 2.3721 mL | |
| 25 mM | 0.0759 mL | 0.3795 mL | 0.7591 mL | 1.8977 mL | |
| 30 mM | 0.0633 mL | 0.3163 mL | 0.6326 mL | 1.5814 mL | |
| 40 mM | 0.0474 mL | 0.2372 mL | 0.4744 mL | 1.1860 mL | |
| 50 mM | 0.0380 mL | 0.1898 mL | 0.3795 mL | 0.9488 mL |
JNJ-7950 Related Classifications
HY-163773 Related Classifications
Powered by Bioz