Chlophedianol hydrochloride
Based on 1 Customer Validation
Chlophedianol (Clofedanol) hydrochloride is an orally active and potent antitussive agent. Chlophedianol hydrochloride can be used for the research of acute cough due to upper respiratory tract infections (URIs).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.67%
- CAS 番号: 511-13-7
- 分子式: C17H21Cl2NO
- 分子量:326.26
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保管条件:
4°C, stored under nitrogen, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
生物活性
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Healthy, adult, male rabbits and cats[1]
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Dosage:2.0, 6.0, 18, 54 and 162 mg/kg (PO) or 1.0, 3.0, 9.0, 27 and 81 mg/kg (SC)
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Administration:Oral or subcutaneous administration, once
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Result:Lowered the volume output of respiratory tract fluid, slightly but significantly over a period of one to three hours after administration. Produced a decrease in the number of animals in which pledgets of mucus appeared in the respiratory tract.
化学情報
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CAS 番号 511-13-7
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性状 Solid
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分子量 326.26
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分子式 C17H21Cl2NO
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Color White to off-white
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SMILES
ClC1=C(C(C2=CC=CC=C2)(CCN(C)C)O)C=CC=C1.Cl
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別名
Clofedanol hydrochloride; Calmotusin hydrochloride; NSC 113595 hydrochloride
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, stored under nitrogen, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
溶剤 & 溶解度
DMSO : 125 mg/mL (383.13 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (276 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0650 mL | 15.3252 mL | 30.6504 mL | 76.6260 mL |
| 5 mM | 0.6130 mL | 3.0650 mL | 6.1301 mL | 15.3252 mL | |
| 10 mM | 0.3065 mL | 1.5325 mL | 3.0650 mL | 7.6626 mL | |
| 15 mM | 0.2043 mL | 1.0217 mL | 2.0434 mL | 5.1084 mL | |
| 20 mM | 0.1533 mL | 0.7663 mL | 1.5325 mL | 3.8313 mL | |
| 25 mM | 0.1226 mL | 0.6130 mL | 1.2260 mL | 3.0650 mL | |
| 30 mM | 0.1022 mL | 0.5108 mL | 1.0217 mL | 2.5542 mL | |
| 40 mM | 0.0766 mL | 0.3831 mL | 0.7663 mL | 1.9157 mL | |
| 50 mM | 0.0613 mL | 0.3065 mL | 0.6130 mL | 1.5325 mL | |
| 60 mM | 0.0511 mL | 0.2554 mL | 0.5108 mL | 1.2771 mL | |
| 80 mM | 0.0383 mL | 0.1916 mL | 0.3831 mL | 0.9578 mL | |
| 100 mM | 0.0307 mL | 0.1533 mL | 0.3065 mL | 0.7663 mL |