1. Anti-infection
  2. Bacterial
    Antibiotic
  3. Sitafloxacin hydrate

Sitafloxacin hydrate (Synonyms: DU6859a hydrate)

Cat. No.: HY-B0395C Purity: >98.0%
Handling Instructions

Sitafloxacin Hydrate is a new-generation, broad-spectrum oral fluoroquinolone antibiotic.

For research use only. We do not sell to patients.

Sitafloxacin hydrate Chemical Structure

Sitafloxacin hydrate Chemical Structure

CAS No. : 163253-35-8

Size Price Stock Quantity
10 mM * 1  mL in DMSO USD 99 In-stock
Estimated Time of Arrival: December 31
5 mg USD 90 In-stock
Estimated Time of Arrival: December 31
10 mg USD 120 In-stock
Estimated Time of Arrival: December 31
50 mg USD 290 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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Customer Review

Based on 3 publication(s) in Google Scholar

Other Forms of Sitafloxacin hydrate:

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Description

Sitafloxacin Hydrate is a new-generation, broad-spectrum oral fluoroquinolone antibiotic. Target: Antibacterial Sitafloxacin Hydrate, a new-generation, broad-spectrum oral fluoroquinolone that is very active against many Gram-positive, Gram-negative and anaerobic clinical isolates, including strains resistant to other fluoroquinolones, was recently approved in Japan for the treatment of respiratory and urinary tract infections [1]. In terms of clinical efficacy, oral sitafloxacin was noninferior to oral levofloxacin in the treatment of community-acquired pneumonia or an infectious exacerbation of chronic respiratory tract disease, noninferior to oral tosufloxacin in the treatment of community-acquired pneumonia, and noninferior to oral levofloxacin in the treatment of complicated urinary tract infections, according to the results of randomized, double-blind, multicentre, noninferiority trials. Noncomparative studies demonstrated the efficacy of oral sitafloxacin in otorhinolaryngological infections, urethritis in men, C. trachomatis-associated cervicitis in women and odontogenic infections [2].

Clinical Trial
Molecular Weight

436.84

Formula

C₁₉H₁₈ClF₂N₃O₃.₃/₂H₂O

CAS No.

163253-35-8

SMILES

N[[email protected]]1C2(CC2)CN(C(C(Cl)=C3N([[email protected]]4[[email protected]@H](F)C4)C=C(C(O)=O)C5=O)=C(C=C35)F)C1.[1.5 H2O]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 8.9 mg/mL (20.37 mM; Need ultrasonic and warming)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2892 mL 11.4458 mL 22.8917 mL
5 mM 0.4578 mL 2.2892 mL 4.5783 mL
10 mM 0.2289 mL 1.1446 mL 2.2892 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Keywords:

SitafloxacinDU6859aBacterialAntibioticInhibitorinhibitorinhibit

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Sitafloxacin hydrate
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HY-B0395C
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