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Cat. No.: HY-B0395E

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(1S,2R,7S)-Sitafloxacin

Name: (1S,2R,7S)-Sitafloxacin
Brand: MedChemExpress
SKU: HY-B0395E
Availability: PreOrder

(Synonyms: (1S,2R,7S)-DU-6859a; DU-6856)

(1S,2R,7S)-Sitafloxacin (DU-6856) is an enantiomer of Sitafloxacin (HY-B0395). (1S,2R,7S)-Sitafloxacin is a topoisomerase inhibitor. (1S,2R,7S)-Sitafloxacin is an antibiotic. (1S,2R,7S)-Sitafloxacin has inhibitory activity against Escherichia coli DNA gyrase (IC50 0.18 μg/mL) and Staphylococcus aureus topoisomerase IV. (1S,2R,7S)-Sitafloxacin has antibacterial activity and can be used in the study of various bacterial infections.

For research use only. We do not sell to patients.

CAS No.: 127254-11-9
Formula: C₁₉H₁₈ClF₂N₃O₃
Molecular Weight:409.81

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

(1S,2R,7S)-Sitafloxacin Chemical Structure

CAS No.: 127254-11-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

All Antibiotic Isoforms :

All Topoisomerase Isoforms :

Chemical Information

CAS No. 127254-11-9
Molecular Weight 409.81
Formula C₁₉H₁₈ClF₂N₃O₃
SMILES

O=C(C1=CN([C@@H]2[C@H](F)C2)C3=C(C=C(F)C(N(C[C@H]4N)CC54CC5)=C3Cl)C1=O)O
Synonyms

(1S,2R,7S)-DU-6859a; DU-6856
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Akasaka T, et al. Antibacterial activities and inhibitory effects of sitafloxacin (DU-6859a) and its optical isomers against type II topoisomerases. Antimicrob Agents Chemother. 1998 May;42(5):1284-7. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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Chemical Information
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References

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(1S,2R,7S)-Sitafloxacin

All Antibiotic Isoforms

All Topoisomerase Isoforms