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  3. Potassium guaiacolsulfonate hemihydrate

Potassium guaiacolsulfonate hemihydrate 

Cat. No.: HY-107798 Purity: 99.83%
COA Handling Instructions

Potassium guaiacolsulfonate hemihydrate is an orally active expectorant used for acute respiratory tract infections. Potassium guaiacolsulfonate hemihydrate helps loosen mucus and used for a cough caused by the common cold, infections or allergies in combination with other agents.

For research use only. We do not sell to patients.

Potassium guaiacolsulfonate hemihydrate Chemical Structure

Potassium guaiacolsulfonate hemihydrate Chemical Structure

CAS No. : 78247-49-1

Size Price Stock Quantity
5 mg USD 25 In-stock
10 mg USD 38 In-stock
25 mg USD 70 In-stock
50 mg USD 100 In-stock
100 mg USD 140 In-stock
200 mg   Get quote  
500 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Potassium guaiacolsulfonate hemihydrate is an orally active expectorant used for acute respiratory tract infections. Potassium guaiacolsulfonate hemihydrate helps loosen mucus and used for a cough caused by the common cold, infections or allergies in combination with other agents[1][2].

In Vitro

Potassium guaiacolsulfonate hemihydrate works by thinning mucus (phlegm) in the lungs and making it less sticky and easier to cough up[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

251.31

Formula

C7H8O5S.1/2H2O.K

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

COC1=CC(S(=O)(O[K])=O)=CC=C1O.COC2=C(C=CC=C2O)S(=O)(O[K])=O.[H]O[H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 62.5 mg/mL (248.70 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.9791 mL 19.8957 mL 39.7915 mL
5 mM 0.7958 mL 3.9791 mL 7.9583 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (397.91 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.83%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 3.9791 mL 19.8957 mL 39.7915 mL 99.4787 mL
5 mM 0.7958 mL 3.9791 mL 7.9583 mL 19.8957 mL
10 mM 0.3979 mL 1.9896 mL 3.9791 mL 9.9479 mL
15 mM 0.2653 mL 1.3264 mL 2.6528 mL 6.6319 mL
20 mM 0.1990 mL 0.9948 mL 1.9896 mL 4.9739 mL
25 mM 0.1592 mL 0.7958 mL 1.5917 mL 3.9791 mL
30 mM 0.1326 mL 0.6632 mL 1.3264 mL 3.3160 mL
40 mM 0.0995 mL 0.4974 mL 0.9948 mL 2.4870 mL
50 mM 0.0796 mL 0.3979 mL 0.7958 mL 1.9896 mL
60 mM 0.0663 mL 0.3316 mL 0.6632 mL 1.6580 mL
80 mM 0.0497 mL 0.2487 mL 0.4974 mL 1.2435 mL
100 mM 0.0398 mL 0.1990 mL 0.3979 mL 0.9948 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Potassium guaiacolsulfonate hemihydrate Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Potassium guaiacolsulfonate hemihydrate
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