Potassium guaiacolsulfonate hemihydrate
Based on 1 Customer Validation
Potassium guaiacolsulfonate hemihydrate is an orally active expectorant used for acute respiratory tract infections. Potassium guaiacolsulfonate hemihydrate helps loosen mucus and used for a cough caused by the common cold, infections or allergies in combination with other agents.
For research use only. We do not sell to patients.
- Purity : 99.83%
- CAS No.: 78247-49-1
- Formula: C7H8O5S.1/2H2O.K
- Molecular Weight:251.31
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
Chemical Information
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CAS No. 78247-49-1
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Appearance Solid
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Molecular Weight 251.31
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Formula C7H8O5S.1/2H2O.K
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Color White to off-white
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SMILES
COC1=CC(S(=O)(O[K])=O)=CC=C1O.COC2=C(C=CC=C2O)S(=O)(O[K])=O.[H]O[H]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
H2O : 62.5 mg/mL (248.70 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo:
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 100 mg/mL (397.91 mM); Clear solution; Need ultrasonic
Purity & Documentation
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Data Sheet (276 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Thi Huong Hoa Le, et al. Development and Validation of an HPLC Method for Simultaneous Assay of Potassium Guaiacolsulfonate and Sodium Benzoate in Pediatric Oral Powder. J Anal Methods Chem. 2019 Mar 7;2019:6143061. [Content Brief]
[2]. Ozlem Aksu Dönmez, et al. Simultaneous Determination of Potassium Guaiacolsulfonate, Guaifenesin, Diphenhydramine HCl and Carbetapentane Citrate in Syrups by Using HPLC-DAD Coupled With Partial Least Squares Multivariate Calibration. Talanta. 2011 Feb 15;83(5):1601-5. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 3.9791 mL | 19.8957 mL | 39.7915 mL | 99.4787 mL |
| 5 mM | 0.7958 mL | 3.9791 mL | 7.9583 mL | 19.8957 mL | |
| 10 mM | 0.3979 mL | 1.9896 mL | 3.9791 mL | 9.9479 mL | |
| 15 mM | 0.2653 mL | 1.3264 mL | 2.6528 mL | 6.6319 mL | |
| 20 mM | 0.1990 mL | 0.9948 mL | 1.9896 mL | 4.9739 mL | |
| 25 mM | 0.1592 mL | 0.7958 mL | 1.5917 mL | 3.9791 mL | |
| 30 mM | 0.1326 mL | 0.6632 mL | 1.3264 mL | 3.3160 mL | |
| 40 mM | 0.0995 mL | 0.4974 mL | 0.9948 mL | 2.4870 mL | |
| 50 mM | 0.0796 mL | 0.3979 mL | 0.7958 mL | 1.9896 mL | |
| 60 mM | 0.0663 mL | 0.3316 mL | 0.6632 mL | 1.6580 mL | |
| 80 mM | 0.0497 mL | 0.2487 mL | 0.4974 mL | 1.2435 mL | |
| 100 mM | 0.0398 mL | 0.1990 mL | 0.3979 mL | 0.9948 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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