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Pathways Recommended:	Stem Cell/Wnt

Results for "

stems and roots

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By Targets:	Bacterial (1) Biochemical Assay Reagents (2) COX (1) Drug Derivative (3) Drug Metabolite (1) Ferroptosis (2) Filovirus (2) Flavivirus (2) Fungal (1) Herbicide (2) Isotope-Labeled Compounds (1) Keap1-Nrf2 (2) Lipoxygenase (1) Parasite (1) Reactive Oxygen Species (ROS) (2) Reference Standards (2)
By Research Areas:	Cancer (5) Cardiovascular Disease (1) Infection (7) Metabolic Disease (1) Neurological Disease (1)

Inhibitors & Agonists

Fluorescent Dyes

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D0955

Thionin acetate Thionine acetate	Biochemical Assay Reagents Bacterial	Infection
Thionin acetate (Thionine acetate) is a compound present in the seeds, stems, roots, and leaves of many plant species with antibacterial activity. Thionin acetate is a metachromatic cationic histological dye widely used in biological staining .

HY-N4118

Cephaeline 1 Publications Verification (-)-Cephaeline; NSC 32944 free base	Filovirus Flavivirus Keap1-Nrf2 Ferroptosis Reactive Oxygen Species (ROS)	Infection Cancer
Cephaeline ((-)-Cephaeline), a desmethyl analog of Emetine, is a phenolic alkaloid in Indian Ipecac roots isolated from the Cephaelis ipecacuanha. Cephaeline exhibits potent inhibition of both Zika virus (ZIKV) and Ebola virus (EBOV) infections. Cephaeline is an inductor of histone H3 acetylation and an inhibitor of mucoepidermoid carcinoma cancer stem cells (MEC), which promotes ferroptosis by inhibiting NRF2 to exert anti-lung cancer efficacy .

HY-N8723

(1′S,2′S)-Nicotine-1'-oxide	Others	Neurological Disease
(1′S,2′S)-Nicotine-1'-oxide is an alkaloid N-oxide from the leaves, stems and roots of Nicotiana tabacum .

HY-N6996S

Methyl Eugenol-13C,d3	Isotope-Labeled Compounds	Others
Methyl Eugenol- ¹³C,d₃ is the ¹³C- and deuterium labeled Methyl Eugenol. Methyl Eugenol, a phenylpropanoid chemical in leaves, fruits, stems, and/or roots, may be released when that corresponding part of a plant is damaged as a result of feeding by an herbivore. Methyl Eugenol is used for male annihilation of the oriental fruit fly .

HY-121211

Digitolutein	Parasite	Infection
Digitolutein is a natural product that can be isolated from the stem bark and the roots of Morinda lucida Benth. Digitolutein effectively inhibits the growth of *Plasmodium falciparum* with an IC₅₀ value of 12.92 μg/mL. Digitolutein can be used for the research of infection .

HY-N4048

Heudelotinone	Others	Cancer
Heudelotinone is a dinorditerpenoid that can be isolated from the stem bark and roots of Ricinodendron heudelotii. Heudelotinone shows cytotoxicity against SMMC-7721, A549 and Hela cells with IC₅₀s of 21.68, 16.04 and 10.67 μM, respectively .

HY-N4118R

Cephaeline (Standard) (-)-Cephaeline (Standard); NSC 32944 free base (Standard)	Reference Standards Filovirus Flavivirus Keap1-Nrf2 Ferroptosis Reactive Oxygen Species (ROS)	Infection Cancer
Cephaeline ((-)-Cephaeline), a desmethyl analog of Emetine, is a phenolic alkaloid in Indian Ipecac roots isolated from the Cephaelis ipecacuanha. Cephaeline exhibits potent inhibition of both Zika virus (ZIKV) and Ebola virus (EBOV) infections. Cephaeline is an inductor of histone H3 acetylation and an inhibitor of mucoepidermoid carcinoma cancer stem cells (MEC), which promotes ferroptosis by inhibiting NRF2 to exert anti-lung cancer efficacy .

HY-136633R

Pyroxasulfone (Standard)	Herbicide Reference Standards	Others
Pyroxasulfone (Standard) is the analytical standard of Pyroxasulfone. This product is intended for research and analytical applications. Pyroxasulfone is a broad-spectrum pyrazole herbicide used primarily for all-season residual weed control in corn and soybeans. Pyroxasulfone is active against a variety of annual grasses and some broad-leaved weeds, and can be absorbed through roots and stems to inhibit early seedling growth of sensitive plants. Pyroxasulfone can be used to study herbicide effects and weed resistance .

HY-W653822

(2'S)-Nicotine 1-oxide (2S)-Nicotine 1-N-oxide	Drug Metabolite	Others
(2'S)-Nicotine 1-oxide ((2S)-Nicotine 1-N-oxide) is an alkaloid N-oxide, which is found in leaves, stems and roots of Nicotiana tabacum .

HY-121728

Langkamide	Others	Others
Langkamide is a novel hypoxia-inducible factor-2 (HIF-2) inhibitory pyrrolidone alkaloid isolated from the roots and stems of Piper sarmentosum, which inhibits HIF-2 transcriptional activity with an EC value of 14.0μM.

HY-N3477

Isokadsurenin D	Others	Others
Isokadsurenin D is a Lignans product that can be isolated from the roots and stems of Kadsura coccinea. .

HY-N9637

Swietenocoumarin I	Others	Others
Swietenocoumarin I (Compound 5) is a coumarin compound that can be found in the combined stem bark and roots of Clausena anisata .

HY-N17844

Rubiasin A	Drug Derivative	Others
Rubiasin A is an anthracene derivative found in the combined roots and stems of Rubia cordifolia. Rubiasin A shows no antiproliferative activity in testing involving colon cancer cells .

HY-N9835

Thymol isobutyrate	Drug Derivative	Infection Cancer
Thymol isobutyrate is a thymol derivative that can be naturally extracted from the essential oil of the roots and aerial parts (leaves, stems, and flowers) of Carpesium cernuum L. This plant's essential oil has antibacterial and cytotoxic activity and can be used in antibacterial and antitumor research .

HY-N19857

Millettiasaponin A	Biochemical Assay Reagents	Cardiovascular Disease Metabolic Disease
Millettiasaponin A is an oleanane-type triterpenoid saponin found in the stems of Derris eriocarpa and roots of Millettia speciosa. Millettiasaponin A is 150 times sweeter than Sucrose (HY-B1779) at 1% concentration. Millettiasaponin A can be used in research on hypertension and obesity. .

HY-167959

MCPA-isooctyl	Herbicide	Infection
MCPA-isooctyl is a selective conductive phenoxycarboxylate herbicide and an alternative to 2,4-D Butyl ester (HY-B0867). MCPA-isooctyl effectively controls broadleaf weeds in various crop fields via post-emergence foliar or soil treatment. MCPA-isooctyl is absorbed by the roots, stems and leaves of plants; it is easily metabolized and detoxified in gramineous crops, but difficult to metabolize in dicotyledonous weeds, causing stem and leaf distortion, root deformation, and eventually weed death. When formulated into chitosan nanoparticles, MCPA-isooctyl still significantly inhibits the growth of weeds in wheat fields, and reduces their chlorophyll content and biomass at low doses .

HY-N19724

Buddledin A	Fungal Lipoxygenase COX	Infection
Buddledin A is a 5-LOX inhibitor (IC₅₀ = 50.4 μM) and a COX inhibitor (IC₅₀ = 13.7 μM). Buddedin A inhibits arachidonic acid metabolism via the 5-LOX and COX pathways, suppresses fungal growth, and exerts toxic effects on fish. Buddedin A may play an ecological role in protecting plant roots and stem barks from fungal infection. Buddedin A can be used in studies related to fungal infections .

HY-N17604

(6aR,11aR)-Edunol	Drug Derivative	Cancer
(6aR,11aR)-Edunol (compound 10) is a pterocarpan and antiproliferative agent. (6aR,11aR)-Edunol can be found in the roots of Lonchocarpus bussei and the stem bark of Lonchocarpus eriocalyx. (6aR,11aR)-Edunol exerts antiproliferative effects against drug-sensitive leukemia cells and multidrug-resistant leukemia cells. (6aR,11aR)-Edunol can be used for the research of leukemia .

Thionin acetate Thionine acetate	Fluorescent Dyes
Thionin acetate (Thionine acetate) is a compound present in the seeds, stems, roots, and leaves of many plant species with antibacterial activity. Thionin acetate is a metachromatic cationic histological dye widely used in biological staining .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N4118

Cephaeline 1 Publications Verification (-)-Cephaeline; NSC 32944 free base	Infection Alkaloids Monophenols other families Classification of Application Fields Phenols Plants Isoquinoline Alkaloids Disease Research Fields Source Classification	Filovirus Flavivirus Keap1-Nrf2 Ferroptosis Reactive Oxygen Species (ROS)
Cephaeline ((-)-Cephaeline), a desmethyl analog of Emetine, is a phenolic alkaloid in Indian Ipecac roots isolated from the Cephaelis ipecacuanha. Cephaeline exhibits potent inhibition of both Zika virus (ZIKV) and Ebola virus (EBOV) infections. Cephaeline is an inductor of histone H3 acetylation and an inhibitor of mucoepidermoid carcinoma cancer stem cells (MEC), which promotes ferroptosis by inhibiting NRF2 to exert anti-lung cancer efficacy .

HY-N8723

(1′S,2′S)-Nicotine-1'-oxide	Natural Products Nicotiana tabacum L. Plants Solanaceae Source Classification	Others
(1′S,2′S)-Nicotine-1'-oxide is an alkaloid N-oxide from the leaves, stems and roots of Nicotiana tabacum .

HY-121211

Digitolutein	Morinda lucida Benth. Rubiaceae Plants	Parasite
Digitolutein is a natural product that can be isolated from the stem bark and the roots of Morinda lucida Benth. Digitolutein effectively inhibits the growth of *Plasmodium falciparum* with an IC₅₀ value of 12.92 μg/mL. Digitolutein can be used for the research of infection .

HY-N4048

Heudelotinone	Ricinodendron heudelotii (Baill.) Heckel Terpenoids Diterpenoids Euphorbiaceae Plants Source Classification	Others
Heudelotinone is a dinorditerpenoid that can be isolated from the stem bark and roots of Ricinodendron heudelotii. Heudelotinone shows cytotoxicity against SMMC-7721, A549 and Hela cells with IC₅₀s of 21.68, 16.04 and 10.67 μM, respectively .

HY-N4118R

Cephaeline (Standard) (-)-Cephaeline (Standard); NSC 32944 free base (Standard)	Alkaloids Structural Classification Monophenols other families Phenols Plants Isoquinoline Alkaloids Source Classification	Reference Standards Filovirus Flavivirus Keap1-Nrf2 Ferroptosis Reactive Oxygen Species (ROS)
Cephaeline ((-)-Cephaeline), a desmethyl analog of Emetine, is a phenolic alkaloid in Indian Ipecac roots isolated from the Cephaelis ipecacuanha. Cephaeline exhibits potent inhibition of both Zika virus (ZIKV) and Ebola virus (EBOV) infections. Cephaeline is an inductor of histone H3 acetylation and an inhibitor of mucoepidermoid carcinoma cancer stem cells (MEC), which promotes ferroptosis by inhibiting NRF2 to exert anti-lung cancer efficacy .

HY-N3477

Isokadsurenin D	Lignans Phenylpropanoids Kadsura coccinea (Lem.) A. C. Smith Plants Schisandraceae Source Classification	Others
Isokadsurenin D is a Lignans product that can be isolated from the roots and stems of Kadsura coccinea. .

HY-N9637

Swietenocoumarin I	Structural Classification Clausena anisata (Willd.) Hook.f. ex Benth. Rutaceae Coumarins Phenylpropanoids Plants Source Classification	Others
Swietenocoumarin I (Compound 5) is a coumarin compound that can be found in the combined stem bark and roots of Clausena anisata .

HY-N17844

Rubiasin A	Structural Classification Ketones, Aldehydes, Acids Rubiaceae Plants Rubia cordifolia L. Source Classification	Drug Derivative
Rubiasin A is an anthracene derivative found in the combined roots and stems of Rubia cordifolia. Rubiasin A shows no antiproliferative activity in testing involving colon cancer cells .

HY-N9835

Thymol isobutyrate	Structural Classification Natural Products Carpesium cernuum L. Plants Compositae Source Classification	Drug Derivative
Thymol isobutyrate is a thymol derivative that can be naturally extracted from the essential oil of the roots and aerial parts (leaves, stems, and flowers) of Carpesium cernuum L. This plant's essential oil has antibacterial and cytotoxic activity and can be used in antibacterial and antitumor research .

HY-N19857

Millettiasaponin A	Triterpenes Structural Classification Leguminosae Terpenoids Brachypterum eriocarpum (F. C. How) Adema & Sirich. Plants Source Classification	Biochemical Assay Reagents
Millettiasaponin A is an oleanane-type triterpenoid saponin found in the stems of Derris eriocarpa and roots of Millettia speciosa. Millettiasaponin A is 150 times sweeter than Sucrose (HY-B1779) at 1% concentration. Millettiasaponin A can be used in research on hypertension and obesity. .

HY-N19724

Buddledin A	Structural Classification Terpenoids Sesquiterpenes Scrophulariaceae Plants Buddleja davidi Franch. Source Classification	Fungal Lipoxygenase COX
Buddledin A is a 5-LOX inhibitor (IC₅₀ = 50.4 μM) and a COX inhibitor (IC₅₀ = 13.7 μM). Buddedin A inhibits arachidonic acid metabolism via the 5-LOX and COX pathways, suppresses fungal growth, and exerts toxic effects on fish. Buddedin A may play an ecological role in protecting plant roots and stem barks from fungal infection. Buddedin A can be used in studies related to fungal infections .

HY-N17604

(6aR,11aR)-Edunol	Structural Classification Flavonoids Plants Other Flavonoids Fabaceae Source Classification	Drug Derivative
(6aR,11aR)-Edunol (compound 10) is a pterocarpan and antiproliferative agent. (6aR,11aR)-Edunol can be found in the roots of Lonchocarpus bussei and the stem bark of Lonchocarpus eriocalyx. (6aR,11aR)-Edunol exerts antiproliferative effects against drug-sensitive leukemia cells and multidrug-resistant leukemia cells. (6aR,11aR)-Edunol can be used for the research of leukemia .

Cat. No.	Product Name	Chemical Structure

HY-N6996S

Methyl Eugenol-13C,d3
Methyl Eugenol- ¹³C,d₃ is the ¹³C- and deuterium labeled Methyl Eugenol. Methyl Eugenol, a phenylpropanoid chemical in leaves, fruits, stems, and/or roots, may be released when that corresponding part of a plant is damaged as a result of feeding by an herbivore. Methyl Eugenol is used for male annihilation of the oriental fruit fly .

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stems and roots

Inhibitors & Agonists

Fluorescent Dyes

NaturalProducts

Isotope-Labeled Compounds

Natural
Products