(1′S,2′S)-Nicotine-1'-oxide

Cat. No.: HY-N8723 Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

(1′S,2′S)-Nicotine-1'-oxide is an alkaloid N-oxide from the leaves, stems and roots of Nicotiana tabacum.

For research use only. We do not sell to patients.

(1′S,2′S)-Nicotine-1'-oxide Chemical Structure

CAS No. : 51095-86-4

Size	Price	Stock	Quantity
1 mg	USD 36	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 76	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 142	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of (1′S,2′S)-Nicotine-1'-oxide:

(1′S,2′S)-Nicotine-1'-oxide-d₃ Get quote

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Biological Activity
Purity & Documentation
References
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Description

(1′S,2′S)-Nicotine-1'-oxide is an alkaloid N-oxide from the leaves, stems and roots of Nicotiana tabacum^[1].

Molecular Weight

178.23

Formula

C₁₀H₁₄N₂O

CAS No.

51095-86-4

Appearance

Solid

Color

White to off-white

SMILES

C[N@@+]1([O-])[C@H](C2=CC=CN=C2)CCC1

Structure Classification

Others

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (561.07 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.6107 mL	28.0536 mL	56.1073 mL
5 mM	1.1221 mL	5.6107 mL	11.2215 mL
10 mM	0.5611 mL	2.8054 mL	5.6107 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (275 KB) SDS (420 KB)

COA (255 KB) HNMR (251 KB) MS (176 KB) OR (171 KB)

Handling Instructions (2659 KB)

References

[1]. B Testa, P Jenner, et al. A reappraisal of the stereoselective metabolism of nicotine to nicotine-1'-N-oxide. Xenobiotica. 1976 Sep;6(9):553-6. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	5.6107 mL	28.0536 mL	56.1073 mL	140.2682 mL
	5 mM	1.1221 mL	5.6107 mL	11.2215 mL	28.0536 mL
	10 mM	0.5611 mL	2.8054 mL	5.6107 mL	14.0268 mL
	15 mM	0.3740 mL	1.8702 mL	3.7405 mL	9.3512 mL
	20 mM	0.2805 mL	1.4027 mL	2.8054 mL	7.0134 mL
	25 mM	0.2244 mL	1.1221 mL	2.2443 mL	5.6107 mL
	30 mM	0.1870 mL	0.9351 mL	1.8702 mL	4.6756 mL
	40 mM	0.1403 mL	0.7013 mL	1.4027 mL	3.5067 mL
	50 mM	0.1122 mL	0.5611 mL	1.1221 mL	2.8054 mL
	60 mM	0.0935 mL	0.4676 mL	0.9351 mL	2.3378 mL
	80 mM	0.0701 mL	0.3507 mL	0.7013 mL	1.7534 mL
	100 mM	0.0561 mL	0.2805 mL	0.5611 mL	1.4027 mL

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(1′S,2′S)-Nicotine-1'-oxide51095-86-4Othersalkaloid N-oxideNicotiana tabacumInhibitorinhibitorinhibit

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(1′S,2′S)-Nicotine-1'-oxide

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Other Forms of (1′S,2′S)-Nicotine-1'-oxide: