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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
23 Results for "
thrombin time
" in MedChemExpress (MCE) Product Catalog:
Products (23)
23 Results for "thrombin time" in MCE Product Catalog:
3
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Cat. No.: HY-N3097
CAS No.: 18836-52-7
Cat. No.: HY-P99794
CAS No.: 2056878-75-0
Synonyms: BAY 1213790
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Cat. No.: HY-N2138
CAS No.: 152580-79-5
Category:
Triterpenes Prosopis juliflora (Sw.) DC. Labiatae Dipsacaceae Terpenoids Dipsacus asper Wall. Plants Disease Research Fields Inflammation/Immunology
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Cat. No.: HY-N3701
CAS No.: 272122-56-2
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Cat. No.: HY-122813
CAS No.: 1015167-40-4
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Dabigatran acyl-β-D-glucuronide is an active metabolite of the thrombin inhibitor Dabigatran (HY-10163). Dabigatran acyl-β-D-glucuronide increases activated partial thromboplastin time (aPTT) in isolated human platelet-poor plasma.
Cat. No.: HY-166257
CAS No.: 38621-58-8
Synonyms: Psychosine 3′-O-sulfate; Psychosine 3′-sulfate
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Lyso-sulfatide (bovine) is a phospholipid component derived from sphingolipid catabolism and a potent factor Xa inhibitor and anticoagulant. Lyso-sulfatide (bovine) binds directly to factor Xa and inhibits prothrombin activation mediated by the prothrombinase complex, thereby prolonging factor Xa-induced plasma clotting time and suppressing thrombin generation. Lyso-sulfatide (bovine) serves as a reliable lipid membrane mimic for studying cell membrane structure, function, and molecular interactions .
Cat. No.: HY-P991169
CAS No.: 2955620-21-8
Synonyms: NXT007; RG6512; RO7589655
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Cat. No.: HY-172905
CAS No.: 885684-79-7
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BCX-3607 is an orally active tissue factor/factor VIIa (TF-FVIIa) inhibitor (IC50: 4 nM). BCX-3607 blocks the extrinsic coagulation pathway by inhibiting the TF-FVIIa complex and significantly prolongs the prothrombin time (PT). BCX-3607 has a higher selectivity for TF-FVIIa than other serine proteases (such as thrombin, FXa, etc.). BCX-3607 can reduce thrombus weight and inflammatory response, and has both anti-thrombotic and anti-inflammatory effects. BCX-3607 can be used in the study of thrombosis-related diseases .
Cat. No.: HY-106404
CAS No.: 205054-36-0
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RPR 130737 is a selective, potent and competitive inhibitor for factor Xa with a Ki of 2.4 nM. RPR 130737 shows selectivity of more than 1000-fold over thrombin, activated protein C, plasmin, tissue-plasminogen activator and trypsin. RPR 130737 can prolong plasma activated partial thromboplastin time and prothrombin time. RPR 130737 shows no effect on platelet aggregation. RPR 130737 can be used for the research of cardiovascular disease, such as thrombosis .
Cat. No.: HY-170485
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Thrombin inhibitor 13 (Compound 13a) is a covalent and reversible inhibitor for thrombin (FIIa) with an IC50 of 0.7 nM. Thrombin inhibitor 13 prolongs the activated partial thromboplastin time (aPTT) and prothrombin time (PT), exhibits antithrombotic and anticoagulant activities .
Cat. No.: HY-P4302
CAS No.: 118253-05-7
Synonyms: Z-Phe-Lys-2,4,6-Trimethylbenzoyloxy-methylketone
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Cat. No.: HY-19674
CAS No.: 363151-21-7
Synonyms: SSR182289A free base
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SSR182289 (SSR182289A free base) is a selective and potent orally active thrombin inhibitor. SSR182289 competitively and selectivity inhibits human thrombin (Ki=0.031 μM). SSR182289 demonstrates anticoagulant activity in vitro (thrombin time EC100=96 nM) and inhibits tissue factor-induced thrombin generation (IC50=0.15 μM) in human plasma. SSR182289 inhibits thrombin-induced aggregation of human platelets (IC50=32 nM), but has no effect on aggregation induced by other platelet agonists .
Cat. No.: HY-19222
CAS No.: 151275-19-3
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CVS-1123 is an orally active direct thrombin inhibitor. CVS-1123 inhibits in vitro platelet aggregation of γ-thrombin and prolongs activated partial thromboplastin time. CVS-1123 alters the thrombotic response to deep vessel wall damage in arterial and venous circulation. CVS-1123 can be used in antithrombotic studies
Cat. No.: HY-N13960
CAS No.: 96440-64-1
Synonyms: Thiolstatin D
Cat. No.: HY-N3097R
CAS No.: 18836-52-7
Cat. No.: HY-19517
CAS No.: 865451-66-7
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R1663 is a factor Xa inhibitor with anticoagulant activity. R1663 does not affect bleeding time. The pharmacodynamic effects (such as inhibition of thrombin generation) and plasma concentrations of R1663 are dose-dependent. R1663 prolongs clotting time in a concentration-dependent manner and inhibits the peak height of thrombin generation and endogenous thrombin potential .
Cat. No.: HY-165360
CAS No.: 1225170-16-0
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JJ1 is a selective α-thrombin inhibitor with a Ki of 0.019 μM. JJ1 directly binds to the active site of α-thrombin to block its catalytic activity. JJ1 exhibits antithrombotic effects and prolongs activated partial thromboplastin time, prothrombin time, and tail bleeding time in mice. JJ1 can be used for the research of thrombotic diseases .
Cat. No.: HY-N3919
CAS No.: 63644-71-3
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Cat. No.: HY-116363A
CAS No.: 121785-72-6
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(21S)-Argatroban is an isomer of Argatroban (HY-B0375) and is a thrombin inhibitor. (21S)-Argatroban can prolong blood clotting time, reduces platelet adhesion and aggregation .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
