Pellitorine (Standard)
Pellitorine (Standard) is the analytical standard of Pellitorine (HY-N3097). Pellitorine is a bioactive natural amide compound. Pellitorine can competitively antagonize the activation of TRPV1 by Capsaicin (HY-10448), thereby reducing pain signal transmission. Pellitorine improves cognitive dysfunction by upregulating the BDNF-ERK1/2-CREB and Nrf2-HO-1 pathways. Pellitorine exerts anti-inflammatory and anti-sepsis effects by inhibiting the release of high mobility group protein B1 (HMGB1) and the expression of RAGE/TLR4. Pellitorine exerts its antithrombotic effect by prolonging the clotting time, inhibiting the activity of clotting factors and thrombin. Pellitorine inhibits lipid peroxidation and resists ferroptosis by upregulating GPX4 and DHODH. Pellitorine kills Aedes aegypti mosquito larvae by inhibiting V-type H⁺-ATPase and aquaporin 4 (AaAQP4). Pellitorine exhibits anti-cancer activity (e.g., leukemia and breast cancer) and has inhibitory effects on certain bacteria.
For research use only. We do not sell to patients.
- CAS No.: 18836-52-7
- Formula: C14H25NO
- Molecular Weight:223.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 18836-52-7
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Molecular Weight 223.35
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Formula C14H25NO
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SMILES
CC(C)CNC(/C=C/C=C/CCCCC)=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
- Pellitorine (Standard)
- 18836-52-7
- Reference Standards
- TRP Channel
- Amyloid-β
- Toll-like Receptor (TLR)
- Keap1-Nrf2
- Heme Oxygenase (HO)
- Dihydroorotate Dehydrogenase
- Ferroptosis
- PAI-1
- NF-κB
- Proton Pump
- Glutathione Peroxidase
- Thrombin
- Insecticide
- Bacterial
- Piper nigrum
- Alkaloids
- cytotoxicity
- Microbial transformation
- Aspergillus niger
- Inhibitor
- inhibitor
- inhibit