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Art. -Nr.: HY-N17623

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Ainsliaeasin C

Ainsliaeasin C, a 7-hydroxycoumarin derivative, is an orally active anticoagulant agent that can be found in Ainsliaea fragrans. Ainsliaeasin C exerts anticoagulant activity both in vitro and in vivo. Ainsliaeasin C can be used for the research on thrombotic disorders.

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CAS. Nr.: 1714097-11-6
Formel: C₁₅H₁₆O₆
Molecular Weight:292.28

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Ainsliaeasin C Chemical Structure

CAS. Nr.: 1714097-11-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
- In Vivo
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

In Vitro

Ainsliaeasin C (0.125-2 mg/mL; 10 min) exhibits in vitro anticoagulant activity in normal human platelet-poor plasma, with a significant prothrombin time (PT) increase at 0.5 mg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Ainsliaeasin C (1 mg/kg; i.g.; daily for 3 days) exhibits in vivo anticoagulant activity in rats, prolonging PT and thrombin time (TT) without causing fatal hemorrhage^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Adult male Wistar rats (250-300 g)^[1]
Dosage:

1 mg/kg
Administration:

i.g.; daily for 3 days
Result:

Did not change the activated partial thromboplastin time (APTT), PT or TT on the third day compared with control.
Prolonged PT to 41.2 seconds and TT to 128.5 seconds on the fifth day after administration.
Caused no deaths in treated rats.

Chemical Information

CAS. Nr. 1714097-11-6
Molecular Weight 292.28
Formel C₁₅H₁₆O₆
SMILES

O=C1C=CC2=CC3=C(O[C@H](C(C)(O)C)[C@@H]3O)C(OC)=C2O1
Structure Classification
- Phenylpropanoids
- Coumarins
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Lei L, et al. Coumarin derivatives from Ainsliaea fragrans and their anticoagulant activity. Sci Rep. 2015;5:13544. Published 2015 Aug 28. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

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100 mg

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