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Cat. No.: HY-N17623

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Ainsliaeasin C

Ainsliaeasin C, a 7-hydroxycoumarin derivative, is an orally active anticoagulant agent that can be found in Ainsliaea fragrans. Ainsliaeasin C exerts anticoagulant activity both in vitro and in vivo. Ainsliaeasin C can be used for the research on thrombotic disorders.

For research use only. We do not sell to patients.

CAS No.: 1714097-11-6
Formula: C₁₅H₁₆O₆
Molecular Weight:292.28

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Ainsliaeasin C Chemical Structure

CAS No.: 1714097-11-6

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Biological Activity
- Description
- In Vitro
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

In Vitro

Ainsliaeasin C (0.125-2 mg/mL; 10 min) exhibits in vitro anticoagulant activity in normal human platelet-poor plasma, with a significant prothrombin time (PT) increase at 0.5 mg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Ainsliaeasin C (1 mg/kg; i.g.; daily for 3 days) exhibits in vivo anticoagulant activity in rats, prolonging PT and thrombin time (TT) without causing fatal hemorrhage^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Adult male Wistar rats (250-300 g)^[1]
Dosage:

1 mg/kg
Administration:

i.g.; daily for 3 days
Result:

Did not change the activated partial thromboplastin time (APTT), PT or TT on the third day compared with control.
Prolonged PT to 41.2 seconds and TT to 128.5 seconds on the fifth day after administration.
Caused no deaths in treated rats.

Chemical Information

CAS No. 1714097-11-6
Molecular Weight 292.28
Formula C₁₅H₁₆O₆
SMILES

O=C1C=CC2=CC3=C(O[C@H](C(C)(O)C)[C@@H]3O)C(OC)=C2O1
Structure Classification
- Phenylpropanoids
- Coumarins
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Lei L, et al. Coumarin derivatives from Ainsliaea fragrans and their anticoagulant activity. Sci Rep. 2015;5:13544. Published 2015 Aug 28. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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