1. Others Cell Cycle/DNA Damage Epigenetics
  2. Isotope-Labeled Compounds HDAC
  3. Tucidinostat-d4

Tucidinostat-d4  (Synonyms: Chidamide-d4; HBI-8000-d4; CS 055-d4)

Cat. No.: HY-109015S Pureza: 98.63%
Instrucciones de manejo Technical Support

Tucidinostat-d4 is the deuterium labeled Tucidinostat. Tucidinostat is a potent and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, respectively.

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Tucidinostat-d<sub>4</sub>

Tucidinostat-d4 Estructura química

No. CAS : 3078846-27-9

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1 mg En stock
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10 mg   Obtener un presupuesto  

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Descripciòn

Tucidinostat-d4 is the deuterium labeled Tucidinostat. Tucidinostat is a potent and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, respectively[1].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

IC50 & Target[1]

HDAC1

95 nM (IC50)

HDAC2

160 nM (IC50)

HDAC3

67 nM (IC50)

HDAC10

78 nM (IC50)

Peso molecular

394.43

Fòrmula

C22H15D4FN4O2

No. CAS
Unlabeled CAS
Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=C([2H])C([2H])=C(CNC(/C=C/C2=CN=CC=C2)=O)C([2H])=C1[2H])NC(C=CC(F)=C3)=C3N

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Pureza y Documentación
Referencias
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  • Calculadora de molaridad

  • Calculadora de dilución

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Nombre del producto:
Tucidinostat-d4
Cat. No.:
HY-109015S
Cantidad:
MCE Japan Authorized Agent: