3078846-27-9
3078846-27-9
Chemical Structure
Tucidinostat-d4
Synonym(s): Chidamide-d4;HBI-8000-d4;CS 055-d4
- CAS No.: 3078846-27-9
- Formula:C22H15D4FN4O2
- Molecular Weight:394.43
IUPAC Name: (E)-N-(2-amino-4-fluorophenyl)-4-((3-(pyridin-3-yl)acrylamido)methyl)benzamide-2,3,5,6-d4
InChIKey: SZMJVTADHFNAIS-NFKQYAPMSA-N
SMILES: O=C(C1=C([2H])C([2H])=C(CNC(/C=C/C2=CN=CC=C2)=O)C([2H])=C1[2H])NC(C=CC(F)=C3)=C3N
Biological Activity: Tucidinostat-d4 is the deuterium labeled Tucidinostat. Tucidinostat is a potent and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Tucidinostat-d4 | 98.63% | Tucidinostat-d4 is the deuterium labeled Tucidinostat. Tucidinostat is a potent and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, respectively. | ||||||||||||||||||||
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Tucidinostat (Standard) | ≥98% | Tucidinostat (Standard) is the analytical standard of Tucidinostat. This product is intended for research and analytical applications. Tucidinostat (Chidamide) is a potent and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, less active on HDAC8 and HDAC11 (IC50s, 733 nM, 432 nM, respectively), and shows no effect on HDAC4/5/6/7/9. | ||||||||||||||||||||
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Tucidinostat | 98.74% | Tucidinostat (Chidamide) is a potent and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, less active on HDAC8 and HDAC11 (IC50s, 733 nM, 432 nM, respectively), and shows no effect on HDAC4/5/6/7/9. | ||||||||||||||||||||
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References
