1. Cell Cycle/DNA Damage
    Epigenetics
  2. HDAC
  3. Tucidinostat D4

Tucidinostat D4 (Synonyms: Chidamide D4; HBI-8000 D4; CS 055 D4)

Cat. No.: HY-109015S
Handling Instructions

Tucidinostat D4 (Chidamide D4) is the deuterium labeled Tucidinostat. Tucidinostat is a potent and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, respectively.

For research use only. We do not sell to patients.

Tucidinostat D4 Chemical Structure

Tucidinostat D4 Chemical Structure

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Description

Tucidinostat D4 (Chidamide D4) is the deuterium labeled Tucidinostat. Tucidinostat is a potent and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, respectively[1].

IC50 & Target[1]

HDAC1

95 nM (IC50)

HDAC2

160 nM (IC50)

HDAC3

67 nM (IC50)

HDAC10

78 nM (IC50)

Molecular Weight

394.43

Formula

C₂₂H₁₅D₄FN₄O₂

SMILES

O=C(C1=C([2H])C([2H])=C(CNC(/C=C/C2=CN=CC=C2)=O)C([2H])=C1[2H])NC(C=CC(F)=C3)=C3N

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Tucidinostat D4Chidamide D4HBI-8000 D4CS 055 D4Tucidinostat D 4Tucidinostat D-4Chidamide D 4Chidamide D-4HDACHistone deacetylasesantitumorHL-60U2OSLNCaPcellscolorectalcarcinomaInhibitorinhibitorinhibit

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Tucidinostat D4
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