2. Others Cell Cycle/DNA Damage Epigenetics
  3. Isotope-Labeled Compounds HDAC
  4. Tucidinostat-d4

Tucidinostat-d4  (Synonyms: Chidamide-d4; HBI-8000-d4; CS 055-d4)

Cat. No.: HY-109015S Purity: 98.63%
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Tucidinostat-d4 is the deuterium labeled Tucidinostat. Tucidinostat is a potent and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, respectively.

For research use only. We do not sell to patients.

Tucidinostat-d<sub>4</sub>

Tucidinostat-d4 Chemical Structure

CAS No. : 3078846-27-9

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Based on 1 publication(s) in Google Scholar

Other Forms of Tucidinostat-d4:

Tucidinostat-d4 Related Antibodies

Top Publications Citing Use of Products

View All HDAC Isoform Specific Products:

View All Isoforms
HDAC HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HDAC7 HDAC8 HDAC9 HDAC10 HDAC11 HD1 HD2

  • Biological Activity

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Description

Tucidinostat-d4 is the deuterium labeled Tucidinostat. Tucidinostat is a potent and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, respectively[1].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

IC50 & Target[1]

HDAC1

95 nM (IC50)

HDAC2

160 nM (IC50)

HDAC3

67 nM (IC50)

HDAC10

78 nM (IC50)

Molecular Weight

394.43

Formula

C22H15D4FN4O2
CAS No.
Unlabeled CAS
Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=C([2H])C([2H])=C(CNC(/C=C/C2=CN=CC=C2)=O)C([2H])=C1[2H])NC(C=CC(F)=C3)=C3N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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Tucidinostat-d4 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tucidinostat-d43078846-27-9Chidamide-d4HBI-8000-d4CS 055-d4Isotope-Labeled CompoundsHDACHistone deacetylasesantitumorHL-60U2OSLNCaPcellscolorectalcarcinomaInhibitorinhibitorinhibit

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