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Results for "

gfr

" in MedChemExpress (MCE) Product Catalog:

15

Inhibitors & Agonists

1

Peptides

3

MCE Kits

1

Inhibitory Antibodies

19

Recombinant Proteins

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0594
    Iohexol
    5 Publications Verification

    Autophagy Mitophagy Cancer
    Iohexol is a non-ionic, water-soluble contrast agent used as a reference marker for the determination of glomerular filtration rate (GFR) at the level of renal function. Iohexol can be used for contrast in myelography, computerized tomography (cisternography, ventriculography) and MicroCT imaging .
    Iohexol
  • HY-P99901

    VIS649

    SARS-CoV Inflammation/Immunology Cancer
    Sibeprenlimab (VIS649) is a humanized IgG2 monoclonal antibody which inhibits a proliferation-inducing ligand (APRIL). Sibeprenlimab suppresses pathogenic immunoglobulins (IgA and IgM), while preserving antibody responses to mRNA-based vaccines against SARS-COV-2. Sibeprenlimab reduces urinary protein-to-creatinine ratio (UPCR) and glomerular filtration rate (GFR). Sibeprenlimab is promising for the research of IgA nephropathy (IgAN) .
    Sibeprenlimab
  • HY-111969
    BT18
    1 Publications Verification

    GDNF Receptor Neurological Disease
    BT18 is a molecule mimic with function similar to glial cell line-derived neurotrophic factor (GDNF) . BT18 shows an effect on GDNF family receptor GFRα1 and RET receptor tyrosine kinase RetA function .
    BT18
  • HY-119910

    XIB4035

    GDNF Receptor Neurological Disease
    (E)-Aminoquinol (XIB4035) is a GFRα-1 agonist. (E)-Aminoquinol has mimic neurotrophic effects of GDNF, and induces Ret autophosphorylation in Neuro-2A cells. (E)-Aminoquinol can be used for research of Parkinson’s disease .
    (E)-Aminoquinol
  • HY-P3624

    Guanylate Cyclase Cardiovascular Disease
    Cenderitide is a potent agonist of particulate guanylyl cyclase receptor (pGC). Cenderitide is a natriuretic peptide (NP) composed of C-type natriuretic peptide (CNP) fused to the C-terminus of Dendroaspis natriuretic peptide (DNP). Cenderitide activates both pGC-A and pGC-B, activates the second messenger cGMP, suppresses aldosterone, and preserves GFR without reducing blood pressure. Cenderitide can be used for heart failure research .
    Cenderitide
  • HY-10657

    Urotensin Receptor Cardiovascular Disease Others
    SB-706375 is an antagonist of the Urotensin II (UII) receptor. By blocking the Urotensin II receptor, SB-706375 reduces the kidney's response to UII and Urotensin-related peptide (URP) and significantly increases the Glomerular Filtration Rate (GFR). SB-706375 can be used in research on kidney diseases and hypertension .
    SB-706375
  • HY-B0594R

    Reference Standards Autophagy Mitophagy Cancer
    Iohexol (Standard) is the analytical standard of Iohexol. This product is intended for research and analytical applications. Iohexol is a non-ionic, water-soluble contrast agent used as a reference marker for the determination of glomerular filtration rate (GFR) at the level of renal function. Iohexol can be used for contrast in myelography, computerized tomography (cisternography, ventriculography) and MicroCT imaging .
    Iohexol (Standard)
  • HY-163840

    GDNF Receptor Neurological Disease
    GFRα2/3-IN-1 (Compound 16) is a selective GFRα2/3 inhibitor with IC50 values of 0.1 and 0.2 μM for GFRα2 and GFRα3, respectively. GFRα2 is a glial cell line-derived neurotrophic factor (GDNF) receptor related to GFRα1, GFRα2/3-IN-1 can be used for pain and itch research .
    GFRα2/3-IN-1
  • HY-100819

    CCR Metabolic Disease
    RO5234444 is an orally active CCR2 antagonist, with IC50s of 22nM for human CCR2 and 161 nM for mouse CCR2. RO5234444 alleviates glomerulosclerosis, reduces albuminuria, and significantly improves the glomerular filtration rate (GFR) in the uninephrectomized (1K) type 2 diabetic db/db mouse model. RO5234444 can be used for the study of type 2 diabetic nephropathy .
    RO5234444
  • HY-RS11664

    Small Interfering RNA (siRNA) Others

    RAPGEF5 Human Pre-designed siRNA Set A contains three designed siRNAs for RAPGEF5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    RAPGEF5 Human Pre-designed siRNA Set A
    RAPGEF5 Human Pre-designed siRNA Set A
  • HY-119910A

    (E/Z)-XIB4035

    GDNF Receptor Neurological Disease
    Aminoquinol is a GFRα-1 agonist. Aminoquinol exhibits neurotrophic effects similar to GDNF and induces Ret autophosphorylation in Neuro-2A cells. Aminoquinol can be used in research related to Parkinson's disease .
    Aminoquinol
  • HY-119910C

    (E/Z)-XIB4035 triphosphate

    GDNF Receptor Neurological Disease
    Aminoquinol ((E/Z)-XIB4035) phosphate is a GFRα-1 agonist. Aminoquinol phosphate exhibits neurotrophic effects similar to GDNF and induces Ret autophosphorylation in Neuro-2A cells. Aminoquinol phosphate can be used in research related to Parkinson's disease .
    Aminoquinol triphosphate
  • HY-119910B

    (E/Z)-XIB4035 phosphate

    GDNF Receptor Neurological Disease
    Aminoquinol ((E/Z)-XIB4035) phosphate is a GFRα-1 agonist. Aminoquinol phosphate exhibits neurotrophic effects similar to GDNF and induces Ret autophosphorylation in Neuro-2A cells. Aminoquinol phosphate can be used in research related to Parkinson's disease .
    Aminoquinol phosphate
  • HY-150652

    FGFR Apoptosis Cancer
    FGFR-IN-8 (Compound 17a) is a highly potent and orally active panFGFR inhibitor against wild-type and mutant FGFRs. FGFR-IN-8 shows inhibition with IC50 values of <0.5, 189.1, <0.5, 22.6, <0.5 and 7.30 nM against FGFR1, V564F-FGFR2, N549H-FGFR2, V555M-FGFR3, FGFR3 and FGFR4, respectively. GFR-IN-8 induces cancer cell apoptosis and shows anticancer activities .
    FGFR-IN-8
  • HY-10657R

    Reference Standards Urotensin Receptor Cardiovascular Disease Others
    SB-706375 (Standard) is the analytical standard of SB-706375 (HY-10657). This product is intended for research and analytical applications. SB-706375 is an antagonist of the Urotensin II (UII) receptor. By blocking the Urotensin II receptor, SB-706375 reduces the kidney's response to UII and Urotensin-related peptide (URP) and significantly increases the Glomerular Filtration Rate (GFR). SB-706375 can be used in research on kidney diseases and hypertension .
    SB-706375 (Standard)

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