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FGFR-IN-8

FGFR-IN-8 (Compound 17a) is a highly potent and orally active panFGFR inhibitor against wild-type and mutant FGFRs. FGFR-IN-8 shows inhibition with IC50 values of <0.5, 189.1, <0.5, 22.6, <0.5 and 7.30 nM against FGFR1, V564F-FGFR2, N549H-FGFR2, V555M-FGFR3, FGFR3 and FGFR4, respectively. GFR-IN-8 induces cancer cell apoptosis and shows anticancer activities.

For research use only. We do not sell to patients.

  • CAS No.: 2640217-64-5
  • Formula: C27H31Cl2N9O2
  • Molecular Weight:584.50
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • FGFR-IN-8 Chemical Structure
    FGFR-IN-8 Chemical Structure
CAS No.: 2640217-64-5
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  • FGFR-IN-8 Chemical Structure
    FGFR-IN-8 Chemical Structure
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  • FGFR-IN-8