1. Signaling Pathways
  2. Protein Tyrosine Kinase/RTK
  3. FGFR
  4. FGFR3 Inhibitors

FGFR3 Inhibitors

FGFR

FGFR1

FGFR2

FGFR3

FGFR4

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform FGFR3 together.

Please try each isoform separately.

FGFR3 Specific Inhibitors
Product Name FGFR3 FGFR1 FGFR2 FGFR4 FGFR3 Selectivity Purity
Nintedanib
FGFR3, IC50: 108 nM
FGFR1, IC50: 69 nM
FGFR2, IC50: 37 nM
  Pan Inhibitor 99.97%
Infigratinib
FGFR3, IC50: 1 nM
FGFR1, IC50: 0.9 nM
FGFR2, IC50: 1.4 nM
FGFR4, IC50: 60 nM
Pan Inhibitor 99.55%
Erdafitinib
FGFR3, IC50: 3.0 nM
FGFR1, IC50: 1.2 nM
FGFR2, IC50: 2.5 nM
FGFR4, IC50: 5.7 nM
Pan Inhibitor 99.66%
PF 477736
FGFR3, IC50: 23 nM
      Pan Inhibitor 99.21%
AZD4547
FGFR3, IC50: 1.8 nM
FGFR1, IC50: 0.2 nM
FGFR2, IC50: 2.5 nM
FGFR4, IC50: 165 nM
Pan Inhibitor 99.68%
Pemigatinib
FGFR3, IC50: 1.2 nM
FGFR1, IC50: 0.4 nM
FGFR2, IC50: 0.5 nM
FGFR4, IC50: 30 nM
Pan Inhibitor 99.88%
Nintedanib esylate
FGFR3, IC50: 108 nM
FGFR1, IC50: 69 nM
FGFR2, IC50: 37 nM
  Pan Inhibitor 99.93%
Futibatinib
FGFR3, IC50: 1.6 nM
FGFR1, IC50: 3.9 nM
FGFR2, IC50: 1.3 nM
wild-type FGFR2, IC50: 0.3 nM
FGFR2 V5651, IC50: 1-3 nM
FGFR2 N550H, IC50: 3.6 nM
FGFR2 E566G, IC50: 2.4 nM
FGFR4, IC50: 8.3 nM
Pan Inhibitor 98.80%
Gandotinib
FGFR3, IC50: 106 nM
 
FGFR2, IC50: 32 nM
  Pan Inhibitor 99.96%
Dovitinib
FGFR3, IC50: 9 nM
FGFR1, IC50: 8 nM
    Pan Inhibitor 97.18%
LY2874455
FGFR3, IC50: 6.4 nM
FGFR1, IC50: 2.8 nM
FGFR2, IC50: 2.6 nM
FGFR4, IC50: 6 nM
Pan Inhibitor 98.06%
BLU9931
FGFR3, IC50: 150 nM
FGFR1, IC50: 591 nM
FGFR2, IC50: 493 nM
FGFR4, IC50: 3 nM
Pan Inhibitor 99.77%
PRN1371
FGFR3, IC50: 4.1 nM
FGFR1, IC50: 0.6 nM
FGFR2, IC50: 1.3 nM
FGFR4, IC50: 19.3 nM
Pan Inhibitor 99.72%
CH5183284
FGFR3, IC50: 22 nM
FGFR1, IC50: 9.3 nM
FGFR2, IC50: 7.6 nM
FGFR4, IC50: 290 nM
Pan Inhibitor 99.73%
Dovitinib lactate
FGFR3, IC50: 9 nM
FGFR1, IC50: 8 nM
    Pan Inhibitor 99.96%
Derazantinib
FGFR3, IC50: 4.5 nM
FGFR1, IC50: 4.5 nM
FGFR2, IC50: 1.8 nM
  Pan Inhibitor 99.18%
FIIN-2
FGFR3, IC50: 27 nM
FGFR1, IC50: 3.1 nM
FGFR2, IC50: 4.3 nM
FGFR4, IC50: 45 nM
Pan Inhibitor 99.95%
S49076
FGFR3, IC50: 15 nM
FGFR1, IC50: 18 nM
FGFR1V561M, IC50: 23 nM
FGFR2, IC50: 17 nM
FGFR2N549H, IC50: 19 nM
  Pan Inhibitor 98.62%
ODM-203
FGFR3, IC50: 6 nM
FGFR1, IC50: 11 nM
FGFR2, IC50: 16 nM
FGFR4, IC50: 35 nM
Pan Inhibitor 99.33%
FIIN-3
FGFR3, IC50: 31.4 nM
FGFR1, IC50: 13.1 nM
FGFR2, IC50: 21 nM
FGFR4, IC50: 35.3 nM
Pan Inhibitor 98.13%
ASP5878
FGFR3, IC50: 0.74 nM
FGFR1, IC50: 0.47 nM
FGFR2, IC50: 0.6 nM
FGFR4, IC50: 3.5 nM
Pan Inhibitor 99.71%
Infigratinib phosphate
FGFR3, IC50: 1 nM
FGFR1, IC50: 0.9 nM
FGFR2, IC50: 1.4 nM
FGFR4, IC50: 60 nM
Pan Inhibitor 97.74%
Rogaratinib
FGFR3
FGFR1
FGFR2
FGFR4
default Inhibitor 99.86%