1. Signaling Pathways
  2. Protein Tyrosine Kinase/RTK
  3. FGFR
  4. FGFR4 Inhibitors

FGFR4 Inhibitors

FGFR

FGFR1

FGFR2

FGFR3

FGFR4

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Sorry. There is currently no product that acts on isoform FGFR4 together.

Please try each isoform separately.

FGFR4 Specific Inhibitors
Product Name FGFR4 FGFR1 FGFR2 FGFR3 FGFR4 Selectivity Purity
Fisogatinib
FGFR4, IC50: 5 nM
      Selective Inhibitor 99.84%
Roblitinib
FGFR4, IC50: 1.9 nM
      Selective Inhibitor 99.33%
BLU9931
FGFR4, IC50: 3 nM
FGFR1, IC50: 591 nM
FGFR2, IC50: 493 nM
FGFR3, IC50: 150 nM
Selective Inhibitor 99.77%
Infigratinib
FGFR4, IC50: 60 nM
FGFR1, IC50: 0.9 nM
FGFR2, IC50: 1.4 nM
FGFR3, IC50: 1 nM
Pan Inhibitor 99.55%
Erdafitinib
FGFR4, IC50: 5.7 nM
FGFR1, IC50: 1.2 nM
FGFR2, IC50: 2.5 nM
FGFR3, IC50: 3.0 nM
Pan Inhibitor 99.66%
AZD4547
FGFR4, IC50: 165 nM
FGFR1, IC50: 0.2 nM
FGFR2, IC50: 2.5 nM
FGFR3, IC50: 1.8 nM
Pan Inhibitor 99.68%
Pemigatinib
FGFR4, IC50: 30 nM
FGFR1, IC50: 0.4 nM
FGFR2, IC50: 0.5 nM
FGFR3, IC50: 1.2 nM
Pan Inhibitor 99.88%
Futibatinib
FGFR4, IC50: 8.3 nM
FGFR1, IC50: 3.9 nM
FGFR2, IC50: 1.3 nM
wild-type FGFR2, IC50: 0.3 nM
FGFR2 V5651, IC50: 1-3 nM
FGFR2 N550H, IC50: 3.6 nM
FGFR2 E566G, IC50: 2.4 nM
FGFR3, IC50: 1.6 nM
Pan Inhibitor 98.80%
LY2874455
FGFR4, IC50: 6 nM
FGFR1, IC50: 2.8 nM
FGFR2, IC50: 2.6 nM
FGFR3, IC50: 6.4 nM
Pan Inhibitor 98.06%
PRN1371
FGFR4, IC50: 19.3 nM
FGFR1, IC50: 0.6 nM
FGFR2, IC50: 1.3 nM
FGFR3, IC50: 4.1 nM
Pan Inhibitor 99.72%
CH5183284
FGFR4, IC50: 290 nM
FGFR1, IC50: 9.3 nM
FGFR2, IC50: 7.6 nM
FGFR3, IC50: 22 nM
Pan Inhibitor 99.73%
FIIN-2
FGFR4, IC50: 45 nM
FGFR1, IC50: 3.1 nM
FGFR2, IC50: 4.3 nM
FGFR3, IC50: 27 nM
Pan Inhibitor 99.95%
ODM-203
FGFR4, IC50: 35 nM
FGFR1, IC50: 11 nM
FGFR2, IC50: 16 nM
FGFR3, IC50: 6 nM
Pan Inhibitor 99.33%
FIIN-3
FGFR4, IC50: 35.3 nM
FGFR1, IC50: 13.1 nM
FGFR2, IC50: 21 nM
FGFR3, IC50: 31.4 nM
Pan Inhibitor 98.13%
ASP5878
FGFR4, IC50: 3.5 nM
FGFR1, IC50: 0.47 nM
FGFR2, IC50: 0.6 nM
FGFR3, IC50: 0.74 nM
Pan Inhibitor 99.71%
Infigratinib phosphate
FGFR4, IC50: 60 nM
FGFR1, IC50: 0.9 nM
FGFR2, IC50: 1.4 nM
FGFR3, IC50: 1 nM
Pan Inhibitor 97.74%
Rogaratinib
FGFR4
FGFR1
FGFR2
FGFR3
default Inhibitor 99.86%