2097512-73-5
2097512-73-5
Chemical Structure
EphB1-IN-2
- CAS No.: 2097512-73-5
- Formula:C17H15ClN4O2
- Molecular Weight:342.78
InChIKey: KAPOOVWPVJRQQM-UHFFFAOYSA-N
SMILES: O=C(CCl)NC1=CC2=NC=NC(NC3=CC(OC)=CC=C3)=C2C=C1
Biological Activity: EphB1-IN-2 is a mutant-selective kinase inhibitor of ABL and FGFR4, with an IC50 of 14 nM against ABLG321C mutant and 163 nM against FGFR4G556C mutant. EphB1-IN-2 shows selectively over wild-type ABL and FGFR4[1][2].
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EphB1-IN-2 | EphB1-IN-2 is a mutant-selective kinase inhibitor of ABL and FGFR4, with an IC50 of 14 nM against ABLG321C mutant and 163 nM against FGFR4G556C mutant. EphB1-IN-2 shows selectively over wild-type ABL and FGFR4. | |||||||||||||||||||||
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References
Keywords
