Mesembrine (Synonyms: (+)-Mesembrine)

Cat. No.: HY-121162: Fiche technique
SDS
Instruction de manipulation
FAQs
Technical Support

Mesembrine ((+)-Mesembrine) a main alkaloid that features an aryloctahydroindole skeleton. Mesembrine is a 5-HT transporter inhibitor with a K_i of 1.4 nM. Mesembrine also inhibits phosphodiesterase 4B (PDE4B) with an IC₅₀ of 7.8 μM.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

Mesembrine Chemical Structure

CAS No. : 468-53-1

Size	Stock
5 mg	Obtenir un devis	Estimated Time of Arrival: December 31
10 mg	Obtenir un devis	Estimated Time of Arrival: December 31
25 mg	Obtenir un devis	Estimated Time of Arrival: December 31

* Veuillez sélectionner la quantité avant d'ajouter des articles.

This product is a controlled substance and not for sale in your territory.

Other Forms of Mesembrine:

(-)-Mesembrine In-stock

Recommandations en vedette

•Related Small Molecules:

•Related Proteins:

Voir tous les produits spécifiques à Isoform 5-HT Receptor:

Voir toutes les isoformes

5-HT Receptor 5-HT₁ Receptor 5-HT₂ Receptor 5-HT₃ Receptor 5-HT₄ Receptor 5-HT₅ Receptor 5-HT₆ Receptor 5-HT₇ Receptor

Voir tous les produits spécifiques à Isoform Phosphodiesterase (PDE):

Voir toutes les isoformes

PDE1 PDE2 PDE3 PDE4 PDE5 PDE6 PDE7 PDE9 PDE10 PDE11 PDE12 PDE8 Autotaxin

Activité biologique
Pureté et documentation
Références
Avis client

Description

IC₅₀ & Target^[1]

PDE4B

7.8 μM (IC₅₀)

serotonin

1.4 nM (Ki)

In Vitro

Mesembrine can bind to cloned human cannabinoid CB1 receptors in vitro^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Masse moléculaire

289.37

Formule

C₁₇H₂₃NO₃

CAS No.

468-53-1

SMILES

O=C1CC[C@]2(C3=CC=C(OC)C(OC)=C3)CCN(C)[C@]2([H])C1

Structure Classification

Initial Source

Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Fiche technique (274 KB) SDS (252 KB) Instruction de manipulation (2659 KB)

Références

[1]. John L Krstenansky. Mesembrine alkaloids: Review of their occurrence, chemistry, and pharmacology. J Ethnopharmacol. 2017 Jan 4;195:10-19. [Content Brief]

[2]. Golo M J Meyer, et al. GC-MS, LC-MS(n), LC-high resolution-MS(n), and NMR studies on the metabolism and toxicological detection of mesembrine and mesembrenone, the main alkaloids of the legal high "Kanna" isolated from Sceletium tortuosum. Anal Bioanal Chem. 2015 Jan;407(3):761-78. [Content Brief]

Mesembrine Related Classifications

Neurological Disease

Calculateur de molarité
Calculateur de dilution

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Mesembrine468-53-1(+)-Mesembrine5-HT ReceptorPhosphodiesterase (PDE)Serotonin Receptor5-hydroxytryptamine ReceptoralkaloidtransporterPDE4Bcannabinoid-CB1Inhibitorinhibitorinhibit

Vos produits récemment consultés:

Nom du produit

Requested Quantity *

Nom du demandeur *

Civilité

Adresse e-mail *

Numéro de téléphone *

Department

Nom de l'organisation *

City

État

Country or Region *

Remarques

Nom du produit

Lot #

Nom du demandeur *

Adresse e-mail *

Numéro de téléphone

Department *