1. Apoptosis
  2. Caspase TNF Receptor
  3. (-)-Isoproterenol

(-)-Isoproterenol  (Synonyms: Levisoprenalinel; Proternol L)

Cat. No.: HY-B1670
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(-)-Isoproterenol (Levisoprenalinel) is the R-isomer of Isoproterenol. (-)-Isoproterenol can reduce the cleavage of caspase 3 and TNFα levels in retinal endothelial cells (REC). (-)-Isoproterenol can be used for the study of diabetic retinopathy.

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(-)-Isoproterenol

(-)-Isoproterenol Estructura química

No. CAS : 51-31-0

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Other In-stock Forms of (-)-Isoproterenol:

Other Forms of (-)-Isoproterenol:

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Descripciòn

(-)-Isoproterenol (Levisoprenalinel) is the R-isomer of Isoproterenol. (-)-Isoproterenol can reduce the cleavage of caspase 3 and TNFα levels in retinal endothelial cells (REC). (-)-Isoproterenol can be used for the study of diabetic retinopathy[1].

IC50 & Target[1]

Caspase 3

 

TNF-α

 

In Vitro

(-)-Isoproterenol (R-1) (10 μM; 15-45 minutes) decreases both TNFα and caspase 3 levels in REC and Müller cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

ELISA Assay[1]

Cell Line: REC cells and Müller cells
Concentration: 10 μM
Incubation Time: 15, 30, and 45 minutes
Result: Significantly decreased caspase 3 levels in REC.
Did not significantly decreased the cleaved caspase 3 levels in Müller cells.
Peso molecular

211.26

Fòrmula

C11H17NO3

No. CAS
SMILES

OC1=CC=C([C@@H](O)CNC(C)C)C=C1O

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
(-)-Isoproterenol
Cat. No.:
HY-B1670
Cantidad:
MCE Japan Authorized Agent: