PKCα (C2-4) inhibitor peptide

Cat. No.: HY-P5881 Purity: 99.50%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

PKCα (C2-4) inhibitor peptide is a PKCα specific inhibitor peptide that blocks the inhibition of I_Kr by the α_1A adrenoreceptor agonist A-61603 (HY-101366).

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

Custom Peptide Synthesis

PKCα (C2-4) inhibitor peptide 화학구조

사이즈	재고	수량
5 mg	해외재고보유	Estimated Time of Arrival: December 31
10 mg	해외재고보유	Estimated Time of Arrival: December 31
25 mg	해외재고보유	Estimated Time of Arrival: December 31
50 mg	해외재고보유	Estimated Time of Arrival: December 31
100 mg	해외재고보유	Estimated Time of Arrival: December 31
200 mg	견적 받기
500 mg	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

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•Related Screening Libraries:

•Related Small Molecules:

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View All PKC Isoform Specific Products:

View All Isoforms

PKC PKCα PKCβ PKCγ PKCδ PKCε PKCη PKCζ PKCθ PKCμ PKC-ι ℩ PKCι

Biological Activity
순도&문서
References
고객리뷰

제품 설명

PKCα (C2-4) inhibitor peptide is a PKCα specific inhibitor peptide that blocks the inhibition of I_Kr by the α_1A adrenoreceptor agonist A-61603 (HY-101366)^[1].

IC₅₀ & Target

PKCα^[1]

분자량

1107.17

화학식

C₄₇H₇₄N₁₄O₁₇

Appearance

Solid

Color

White to off-white

Sequence

Ser-Leu-Asn-Pro-Glu-Tyr-Arg-Gln-Thr

Sequence Shortening

SLNPEYRQT

선적

Room temperature in continental US; may vary elsewhere.

보관

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

용액&용해도

In Vitro:

DMSO : 100 mg/mL (90.32 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.9032 mL	4.5160 mL	9.0320 mL
5 mM	0.1806 mL	0.9032 mL	1.8064 mL
10 mM	0.0903 mL	0.4516 mL	0.9032 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

순도&문서

Purity: 99.50%

Select Batch:

Data Sheet (276 KB) SDS (252 KB)

COA (257 KB) LCMS (91 KB) Elemental Analysis Report (114 KB)

Handling Instructions (2659 KB)

References

[1]. Liu X, et al. Different protein kinase C isoenzymes mediate inhibition of cardiac rapidly activating delayed rectifier K+ current by different G-protein coupled receptors. Br J Pharmacol. 2017 Dec;174(23):4464-4477. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	0.9032 mL	4.5160 mL	9.0320 mL	22.5801 mL
	5 mM	0.1806 mL	0.9032 mL	1.8064 mL	4.5160 mL
	10 mM	0.0903 mL	0.4516 mL	0.9032 mL	2.2580 mL
	15 mM	0.0602 mL	0.3011 mL	0.6021 mL	1.5053 mL
	20 mM	0.0452 mL	0.2258 mL	0.4516 mL	1.1290 mL
	25 mM	0.0361 mL	0.1806 mL	0.3613 mL	0.9032 mL
	30 mM	0.0301 mL	0.1505 mL	0.3011 mL	0.7527 mL
	40 mM	0.0226 mL	0.1129 mL	0.2258 mL	0.5645 mL
	50 mM	0.0181 mL	0.0903 mL	0.1806 mL	0.4516 mL
	60 mM	0.0151 mL	0.0753 mL	0.1505 mL	0.3763 mL
	80 mM	0.0113 mL	0.0565 mL	0.1129 mL	0.2823 mL