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Results for "

bronchial+asthma

" in MedChemExpress (MCE) Product Catalog:

47

Inhibitors & Agonists

1

Screening Libraries

1

Biochemical Assay Reagents

1

Peptides

4

Natural
Products

3

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0468
    Isoprenaline hydrochloride
    Maximum Cited Publications
    87 Publications Verification

    Isoproterenol hydrochloride

    		 Adrenergic Receptor Endogenous Metabolite Cardiovascular Disease Endocrinology
    Isoprenaline (Isoproterenol) hydrochloride is a non-selective, orally active β-adrenergic receptor agonist. Isoprenaline has potent peripheral vasodilator, bronchodilator, and cardiac stimulating activities. Isoprenaline can be used for the research of bradycardia and bronchial asthma .
    Isoprenaline hydrochloride
  • HY-A0062
    Telithromycin
    5 Publications Verification

    HMR3647; RU66647

    		 Bacterial Antibiotic Infection Inflammation/Immunology
    Telithromycin (HMR3647) is a novel ketolide antibiotic that structurally resembles macrolides. Telithromycin belongs to the ketolide family that is characterized by a keto group at position 3 of the macrolide ring and is active against bacteria causing community-acquired pneumonia, acute exacerbation of chronic bronchitis, and acute sinusitis. Telithromycin also has similar immunomodulatory effects as macrolides. Telithromycin can be used for the research of respiratory infections including bronchial asthma .
    Telithromycin
  • HY-B0320A
    Cromolyn disodium
    5+ Cited Publications

    Cromoglycate disodium; Cromoglicic acid disodium; FPL-670

    		 GSK-3 NF-κB Amyloid-β Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    Cromolyn (Cromoglycate) disodium is an orally active GSK-3β inhibitor with an IC50 of 2.0 μM. Cromolyn disodium is also a mast cell stabilizer that can inhibit the release of mediators from mast cells, regulate reflex bronchoconstriction, and reduce non-specific bronchial hyperreactivity, and Cromolyn disodium can be used in the research of bronchial asthma. In addition, Cromolyn disodium has multiple activities such as anti-inflammatory, anti-allergic, anti-histamine, anti-cancer, and neuroprotective effects .
    Cromolyn disodium
  • HY-108353
    Isoprenaline
    Maximum Cited Publications
    87 Publications Verification

    		 Adrenergic Receptor Endogenous Metabolite Cardiovascular Disease Endocrinology
    Isoprenaline is a non-selective, orally active β-adrenergic receptor agonist. Isoprenaline has potent peripheral vasodilator, bronchodilator, and cardiac stimulating activities. Isoprenaline can be used for the research of bradycardia and bronchial asthma .
    Isoprenaline
  • HY-P2232
    Conalbumin

    Ovotransferrin

    		 Bacterial Cardiovascular Disease Infection Metabolic Disease Inflammation/Immunology Cancer
    Conalbumin (Ovotransferrin) is an iron-binding protein present in egg white with antibacterial activity. Conalbumin can also be used to induce bronchial asthma. Conalbumin exhibits induced mRNA accumulation in chicken oviduct cells by estrogen and progesterone .
    Conalbumin
  • HY-Y0912
    HBTU

    N-HBTU

    		 Biochemical Assay Reagents Inflammation/Immunology
    HBTU (N-HBTU) is a guanidinium-based peptide coupling reagent and immunological sensitizer. HBTU can be used in combination with bases such as DIPEA (HY-130142) to complete coupling reactions, with HOBt and TMU as by-products. HBTU is a standard reagent in automated solid-phase peptide synthesis, particularly for the Fmoc/tBu strategy, which effectively promotes coupling steps, but it is not suitable for sterically hindered amino acids or dipeptide derivatives. HBTU can induce rhinitis, dermatitis, bronchial asthma and severe allergic reactions. HBTU can be used to study the pathogenesis of allergic reactions, occupational rhinitis, allergic contact dermatitis and bronchial asthma .
    HBTU
  • HY-B1810
    Tulobuterol
    2 Publications Verification

    C-78 free base

    		 Adrenergic Receptor Inflammation/Immunology Endocrinology
    Tulobuterol (C-78 free base) is a long-acting β2-adrenoceptor agonist, which reduces the frequency of exacerbations of chronic obstructive pulmonary disease and bronchial asthma. Tulobuterol is also a sympathomimetic agent used as a transdermal patch, and increases normal diaphragm muscle strength .
    Tulobuterol
  • HY-B0010
    Formoterol fumarate
    5+ Cited Publications

    (±)Formoterol fumarate

    		 Adrenergic Receptor Inflammation/Immunology
    Formoterol fumarate ((±)Formoterol fumarate) is a selective β2-adrenoceptor agonist. Formoterol fumarate is at least as β2-adrenoceptor selective as Salbutamol (HY-B1037) and Terbutaline (HY-B0802A). Formoterol fumarate abolishs the contraction induced by Acetylcholine in bronchioles. Formoterol fumarate can be used for the research of chronic obstructive pulmonary disease and bronchial asthma .
    Formoterol fumarate
  • HY-12642
    Diethylcarbamazine citrate
    1 Publications Verification

    		 Parasite Bacterial TNF Receptor Interleukin Related Infection Metabolic Disease Inflammation/Immunology
    Diethylcarbamazine citrate is an orally active microfilaricidal agent used originally in onchocerciasis and lymphatic filiariasis. Diethylcarbamazine citrate reduces eosinophil trafficking to the lung tissue and exerts anti-allergic effects. Diethylcarbamazine citrate reduces serum levels of leptin, TNF-α, IL-6, MCP-1, glucose, insulin, and triglycerides, and ameliorates insulin resistance without altering body, liver, or adipose tissue weights. Diethylcarbamazine citrate enhances reactive oxygen intermediate expression by polymorphonuclear neutrophils, increases lymphocyte proliferation, and inhibits actinomycetoma lesion development. Diethylcarbamazine citrate can be used for the researches of bronchial asthma, insulin resistance and infection .
    Diethylcarbamazine citrate
  • HY-16768
    Fevipiprant
    1 Publications Verification

    QAW039; NVP-QAW039

    		 Prostaglandin Receptor Cardiovascular Disease
    Fevipiprant (QAW039, NVP-QAW039) is s an orally active, selective, reversible prostaglandin D2 (DP2) receptor antagonist with an Kd value of 1.14 nM. Fevipiprant has the potential for the research of bronchial asthma .
    Fevipiprant
  • HY-B1619
    Cromolyn
    5+ Cited Publications

    Cromoglycate; Cromoglicic acid; FPL-670 free acid

    		 GSK-3 NF-κB Amyloid-β Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    Cromolyn (Cromoglycate) is an orally active GSK-3β inhibitor with an IC50 of 2.0 μM. Cromolyn is also a mast cell stabilizer that can inhibit the release of mediators from mast cells, regulate reflex bronchoconstriction, and reduce non-specific bronchial hyperreactivity, and Cromolyn can be used in the research of bronchial asthma. In addition, Cromolyn has multiple activities such as anti-inflammatory, anti-allergic, anti-histamine, anti-cancer, and neuroprotective effects .
    Cromolyn
  • HY-B0538A
    Pemirolast potassium

    TWT-8152; BMY 26517

    		 Histamine Receptor Cardiovascular Disease Inflammation/Immunology
    Pemirolast potassium is an orally active antiallergic agent. Pemirolast potassium attenuates Paclitaxel (HY-B0015) hypersensitivity reactions. Pemirolast potassium can be used for bronchial asthma and conjunctivitis research - .
    Pemirolast potassium
  • HY-W011733
    Tulobuterol hydrochloride
    2 Publications Verification

    C-78

    		 Adrenergic Receptor Influenza Virus Antibiotic Infection Inflammation/Immunology Endocrinology
    Tulobuterol hydrochloride (C-78) is a long-acting β2-adrenoceptor agonist, which reduces the frequency of exacerbations of chronic obstructive pulmonary disease and bronchial asthma. Tulobuterol hydrochloride is also a sympathomimetic agent used as a transdermal patch, increases normal diaphragm muscle strength . Tulobuterol hydrochloride inhibit rhinovirus replication and modulate airway inflammation .
    Tulobuterol hydrochloride
  • HY-12642A
    Diethylcarbamazine
    1 Publications Verification

    		 Parasite Bacterial TNF Receptor Interleukin Related Infection Metabolic Disease Inflammation/Immunology
    Diethylcarbamazine is an orally active microfilaricidal agent used originally in onchocerciasis and lymphatic filiariasis. Diethylcarbamazine reduces eosinophil trafficking to the lung tissue and exerts anti-allergic effects. Diethylcarbamazine reduces serum levels of leptin, TNF-α, IL-6, MCP-1, glucose, insulin, and triglycerides, and ameliorates insulin resistance without altering body, liver, or adipose tissue weights. Diethylcarbamazine enhances reactive oxygen intermediate expression by polymorphonuclear neutrophils, increases lymphocyte proliferation, and inhibits actinomycetoma lesion development. Diethylcarbamazine can be used for the researches of bronchial asthma, insulin resistance and infection .
    Diethylcarbamazine
  • HY-109544
    Repirinast

    MY-5116

    		 Histamine Receptor Inflammation/Immunology
    Repirinast (MY-5116) is an orally active anti-allergic agent. Repirinast inhibits histamine release. Repirinast can be used in the research of bronchial asthma .
    Repirinast
  • HY-18706
    trans-Tranilast

    trans-MK-341; trans-SB 252218

    		 Angiotensin Receptor Drug Isomer Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
    trans-Tranilast (trans-MK-341) is an isomer of Tranilast (HY-B0195), and an anti-allergy agent used in studies of bronchial asthma, allergic rhinitis, and atopic dermatitis .
    trans-Tranilast
  • HY-A0075
    Decloxizine dihydrochloride
    1 Publications Verification

    UCB 1402 dihydrochloride; NSC289116 dihydrochloride

    		 Histamine Receptor 5-HT Receptor Inflammation/Immunology
    Decloxizine (UCB-1402; NSC289116) dihydrochloride is an orally active bronchodilator that can penetrate the blood-brain barrier. Decloxizine dihydrochloride is a piperazine-type H1 histamine receptor antagonist. Decloxizine dihydrochloride selectively blocks H1 histamine receptors, inhibiting histamine-induced capillary dilation, edema, and itching. Decloxizine dihydrochloride has some 5-HT2 receptor antagonistic activity. Decloxizine dihydrochloride can be used in studies of urticaria, allergic rhinitis, and bronchial asthma .
    Decloxizine dihydrochloride
  • HY-119995
    Chloropyramine

    		Apoptosis Histamine Receptor Cardiovascular Disease Cancer
    Chloropyramine is competitive reversible H1 receptor antagonist. Chloropyramine also has anti-tumour activity in breast cancer. Chloropyramine can be used for the research of allergic conditions, such as conjunctivitis and bronchial asthma .
    Chloropyramine
  • HY-108353A
    Isoprenaline hemisulfate
    Maximum Cited Publications
    87 Publications Verification

    		 Adrenergic Receptor Endogenous Metabolite Cardiovascular Disease Endocrinology
    Isoprenaline hemisulfate is a non-selective, orally active β-adrenergic receptor agonist. Isoprenaline has potent peripheral vasodilator, bronchodilator, and cardiac stimulating activities. Isoprenaline can be used for the research of bradycardia and bronchial asthma .
    Isoprenaline hemisulfate
  • HY-176800
    LMD-902

    		CCR Neurological Disease Inflammation/Immunology
    LMD-902, a LMD-009 (HY-121885) analog, is a CCR8 agonist with an EC50 of 15  nM. LMD-902 has a superior binging capacity depending on key residues such as PheVI:16. LMD-902 can be used for inflammation diseases like bronchial asthma and central nervous system diseases like multiple sclerosis research .
    LMD-902
  • HY-B0320AR
    Cromolyn disodium (Standard)

    Cromoglycate disodium (Standard); Cromoglicic acid disodium (Standard); FPL-670 (Standard)

    		 Reference Standards GSK-3 NF-κB Amyloid-β Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    Cromolyn disodium (Standard) (Cromoglycate disodium (Standard)) is the analytical standard of Cromolyn disodium (HY-B0320A). This product is intended for research and analytical applications. Cromolyn (Cromoglycate) disodium is an orally active GSK-3β inhibitor with an IC50 of 2.0 μM. Cromolyn disodium is also a mast cell stabilizer that can inhibit the release of mediators from mast cells, regulate reflex bronchoconstriction, and reduce non-specific bronchial hyperreactivity, and Cromolyn disodium can be used in the research of bronchial asthma. In addition, Cromolyn disodium has multiple activities such as anti-inflammatory, anti-allergic, anti-histamine, anti-cancer, and neuroprotective effects .
    Cromolyn disodium (Standard)
  • HY-B0468R
    Isoprenaline hydrochloride (Standard)

    Isoproterenol hydrochloride (Standard)

    		 Reference Standards Adrenergic Receptor Endogenous Metabolite Cardiovascular Disease Endocrinology
    Isoprenaline (hydrochloride) (Standard) is the analytical standard of Isoprenaline (hydrochloride). This product is intended for research and analytical applications. Isoprenaline (Isoproterenol) hydrochloride is a non-selective, orally active β-adrenergic receptor agonist. Isoprenaline has potent peripheral vasodilator, bronchodilator, and cardiac stimulating activities. Isoprenaline can be used for the research of bradycardia and bronchial asthma .
    Isoprenaline hydrochloride (Standard)
  • HY-170397
    ADORA2A/PDE4D-IN-1

    		Phosphodiesterase (PDE) Adenosine Receptor Inflammation/Immunology
    ADORA2A/PDE4D-IN-1 (Compound 9) is a dual inhibitor for adenosine A2a receptor (ADORA2A) and phosphodiesterase 4D (PDE4D). ADORA2A/PDE4D-IN-1 can be used in research of bronchial asthma .
    ADORA2A/PDE4D-IN-1
  • HY-17582
    Decloxizine
    1 Publications Verification

    UCB-1402; NSC289116

    		 Histamine Receptor 5-HT Receptor Inflammation/Immunology
    Decloxizine (UCB-1402; NSC289116) is an orally active bronchodilator that can penetrate the blood-brain barrier. Decloxizine is a piperazine-type H1 histamine receptor antagonist. Decloxizine selectively blocks H1 histamine receptors, inhibiting histamine-induced capillary dilation, edema, and itching. Decloxizine has some 5-HT2 receptor antagonistic activity. Decloxizine can be used in studies of urticaria, allergic rhinitis, and bronchial asthma .
    Decloxizine
  • HY-B1619R
    Cromolyn (Standard)

    Cromoglycate (Standard); Cromoglicic acid (Standard); FPL-670 free acid (Standard)

    		 GSK-3 NF-κB Amyloid-β Reference Standards Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    Cromolyn (Standard) is the analytical standard of Cromolyn. This product is intended for research and analytical applications. Cromolyn (Cromoglycate) is an orally active GSK-3β inhibitor with an IC50 of 2.0 μM. Cromolyn is also a mast cell stabilizer that can inhibit the release of mediators from mast cells, regulate reflex bronchoconstriction, and reduce non-specific bronchial hyperreactivity, and Cromolyn can be used in the research of bronchial asthma. In addition, Cromolyn has multiple activities such as anti-inflammatory, anti-allergic, anti-histamine, anti-cancer, and neuroprotective effects .
    Cromolyn (Standard)
  • HY-101235
    ICI 185282

    		Prostaglandin Receptor Cardiovascular Disease Inflammation/Immunology
    ICI 185282 is a potent, selective, orally active thromboxane A2 (TXA₂) receptor antagonist. ICI 185282 causes dose-dependent inhibition of U-46619 (HY-108566)-induced platelet aggregation ex-vivo in guinea-pig. ICI 185,282 inhibits bronchospasm induced by U-46619, PGD2 (HY-101988), PGF2α (HY-12956), arachidonic acid (HY-109590), LTD4 and PAF (HY-108635) in vivo. ICI 185282 can be used for bronchial asthma research .
    ICI 185282
  • HY-137863
    Pemirolast

    		Histamine Receptor Cardiovascular Disease Inflammation/Immunology
    Pemirolast is an orally active antiallergic agent. Pemirolast attenuates Paclitaxel (HY-B0015) hypersensitivity reactions. Pemirolast can be used for bronchial asthma and conjunctivitis research - .
    Pemirolast
  • HY-120521
    Urodilatin

    		Natriuretic Peptide Receptor (NPR) Neurological Disease
    Urodilatin is an analogue of ANF-(99-126). Urodilatin is a diuretic-natriuretic regulatory peptide. Urodilatin can be used for research of acute renal failure, congestive heart failure, and bronchial asthma, etc .
    Urodilatin
  • HY-105790
    Piperilate

    Pipethanate

    		 Cholinesterase (ChE) Cardiovascular Disease
    Piperilate (Pipethanate) is one of the mixtures of hetrazepine derivative PAF antagonists with anticholinergics, can be used for bronchial asthma research. Piperilate also causes hypotension and rescues mice poisoned by the organophosphates .
    Piperilate
  • HY-117862
    TASP0412098

    		Prostaglandin Receptor Inflammation/Immunology
    TASP0412098 is an orally available, potent and selective CRTH2/DP2 antagonist with high binding affinity (IC50 2.1 nM) and functional activity (IC50 12 nM). TASP0412098 has the potential to suppress asthma in mouse and guinea pig bronchial asthma models .
    TASP0412098
  • HY-B0468S
    Isoprenaline-d7 hydrochloride

    Isoproterenol-d7 hydrochloride

    		 Isotope-Labeled Compounds Endogenous Metabolite Adrenergic Receptor Cardiovascular Disease
    Isoprenaline-d7 (hydrochloride) is a deuterated labeled Isoprenaline (hydrochloride) . Isoprenaline (Isoproterenol) hydrochloride is a non-selective, orally active β-adrenergic receptor agonist. Isoprenaline has potent peripheral vasodilator, bronchodilator, and cardiac stimulating activities. Isoprenaline can be used for the research of bradycardia and bronchial asthma .
    Isoprenaline-d7 hydrochloride
  • HY-B1810S
    Tulobuterol-d9 hydrochloride

    C-78-d9

    		 Isotope-Labeled Compounds Adrenergic Receptor Inflammation/Immunology Endocrinology
    Tulobuterol-d9 (hydrochloride) is the deuterium labeled Tulobuterol. Tulobuterol (C-78 free base) is a long-acting β2-adrenoceptor agonist, which reduces the frequency of exacerbations of chronic obstructive pulmonary disease and bronchial asthma. Tulobuterol is also a sympathomimetic agent used as a transdermal patch, and increases normal diaphragm muscle strength .
    Tulobuterol-d9 hydrochloride
  • HY-B1810R
    Tulobuterol (Standard)

    C-78 free base (Standard)

    		 Reference Standards Adrenergic Receptor Inflammation/Immunology Endocrinology
    Tulobuterol (Standard) is the analytical standard of Tulobuterol. This product is intended for research and analytical applications. Tulobuterol (C-78 free base) is a long-acting β2-adrenoceptor agonist, which reduces the frequency of exacerbations of chronic obstructive pulmonary disease and bronchial asthma. Tulobuterol is also a sympathomimetic agent used as a transdermal patch, and increases normal diaphragm muscle strength .
    Tulobuterol (Standard)
  • HY-W011733R
    Tulobuterol hydrochloride (Standard)

    C-78 (Standard)

    		 Reference Standards Adrenergic Receptor Influenza Virus Antibiotic Infection Inflammation/Immunology Endocrinology
    Tulobuterol (hydrochloride) (Standard) is the analytical standard of Tulobuterol (hydrochloride). This product is intended for research and analytical applications. Tulobuterol hydrochloride (C-78) is a long-acting β2-adrenoceptor agonist, which reduces the frequency of exacerbations of chronic obstructive pulmonary disease and bronchial asthma. Tulobuterol hydrochloride is also a sympathomimetic agent used as a transdermal patch, increases normal diaphragm muscle strength . Tulobuterol hydrochloride inhibit rhinovirus replication and modulate airway inflammation .
    Tulobuterol hydrochloride (Standard)
  • HY-A0062R
    Telithromycin (Standard)

    HMR3647 (Standard); RU66647 (Standard)

    		 Reference Standards Bacterial Antibiotic Infection Inflammation/Immunology
    Telithromycin (Standard) is the analytical standard of Telithromycin. This product is intended for research and analytical applications. Telithromycin (HMR3647) is a novel ketolide antibiotic that structurally resembles macrolides. Telithromycin belongs to the ketolide family that is characterized by a keto group at position 3 of the macrolide ring and is active against bacteria causing community-acquired pneumonia, acute exacerbation of chronic bronchitis, and acute sinusitis. Telithromycin also has similar immunomodulatory effects as macrolides. Telithromycin can be used for the research of respiratory infections including bronchial asthma .
    Telithromycin (Standard)
  • HY-17582R
    Decloxizine (Standard)

    UCB-1402 (Standard); NSC289116 (Standard)

    		 Reference Standards Histamine Receptor 5-HT Receptor Metabolic Disease Inflammation/Immunology
    Decloxizine (UCB-1402; NSC289116) (Standard) is the analytical standard of Decloxizine. This product is intended for research and analytical applications.Decloxizine is an orally active bronchodilator that can penetrate the blood-brain barrier. Decloxizine is a piperazine-type H1 histamine receptor antagonist. Decloxizine selectively blocks H1 histamine receptors, inhibiting histamine-induced capillary dilation, edema, and itching. Decloxizine has some 5-HT2 receptor antagonistic activity. Decloxizine can be used in studies of urticaria, allergic rhinitis, and bronchial asthma.
    Decloxizine (Standard)
  • HY-B1619S
    Cromolyn-d5

    Cromoglycate-d5; Cromoglicic acid-d5; FPL-670-d5 free acid

    		 Isotope-Labeled Compounds GSK-3 NF-κB Amyloid-β Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    Cromolyn-d5 (Cromoglycate-d5) is the deuterium labeled Cromolyn (HY-B1619). Cromolyn (Cromoglycate) is an orally active GSK-3β inhibitor with an IC50 of 2.0 μM. Cromolyn is also a mast cell stabilizer that can inhibit the release of mediators from mast cells, regulate reflex bronchoconstriction, and reduce non-specific bronchial hyperreactivity, and Cromolyn can be used in the research of bronchial asthma. In addition, Cromolyn has multiple activities such as anti-inflammatory, anti-allergic, anti-histamine, anti-cancer, and neuroprotective effects .
    Cromolyn-d5
  • HY-W276446
    1,1-Diphenyl-4-(pyrrolidin-1-yl)but-2-yn-1-ol

    		Cholinesterase (ChE) Inflammation/Immunology
    1,1-Diphenyl-4-(pyrrolidin-1-yl)but-2-yn-1-ol is an anticholinergic agent. 1,1-Diphenyl-4-(pyrrolidin-1-yl)but-2-yn-1-ol has the potential for the research of bronchial asthma . 1,1-Diphenyl-4-(pyrrolidin-1-yl)but-2-yn-1-ol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    1,1-Diphenyl-4-(pyrrolidin-1-yl)but-2-yn-1-ol
  • HY-12642AR
    Diethylcarbamazine (Standard)

    		Reference Standards Parasite Bacterial TNF Receptor Interleukin Related Infection Metabolic Disease Inflammation/Immunology
    Diethylcarbamazine (Standard) is the analytical standard of Diethylcarbamazine (HY-12642A). This product is intended for research and analytical applications. Diethylcarbamazine is an orally active microfilaricidal agent used originally in onchocerciasis and lymphatic filiariasis. Diethylcarbamazine reduces eosinophil trafficking to the lung tissue and exerts anti-allergic effects. Diethylcarbamazine reduces serum levels of leptin, TNF-α, IL-6, MCP-1, glucose, insulin, and triglycerides, and ameliorates insulin resistance without altering body, liver, or adipose tissue weights. Diethylcarbamazine enhances reactive oxygen intermediate expression by polymorphonuclear neutrophils, increases lymphocyte proliferation, and inhibits actinomycetoma lesion development. Diethylcarbamazine can be used for the researches of bronchial asthma, insulin resistance and infection .
    Diethylcarbamazine (Standard)
  • HY-12642R
    Diethylcarbamazine citrate (Standard)

    		Reference Standards Parasite Bacterial TNF Receptor Interleukin Related Infection Metabolic Disease Inflammation/Immunology
    Diethylcarbamazine citrate (Standard) is the analytical standard of Diethylcarbamazine citrate (HY-12642). This product is intended for research and analytical applications. Diethylcarbamazine citrate is an orally active microfilaricidal agent used originally in onchocerciasis and lymphatic filiariasis. Diethylcarbamazine citrate reduces eosinophil trafficking to the lung tissue and exerts anti-allergic effects. Diethylcarbamazine citrate reduces serum levels of leptin, TNF-α, IL-6, MCP-1, glucose, insulin, and triglycerides, and ameliorates insulin resistance without altering body, liver, or adipose tissue weights. Diethylcarbamazine citrate enhances reactive oxygen intermediate expression by polymorphonuclear neutrophils, increases lymphocyte proliferation, and inhibits actinomycetoma lesion development. Diethylcarbamazine citrate can be used for the researches of bronchial asthma, insulin resistance and infection .
    Diethylcarbamazine citrate (Standard)
  • HY-105790A
    Piperilate hydrochloride

    		Cholinesterase (ChE) Cardiovascular Disease
    Piperilate (Pipethanate) hydrochloride is one of the mixtures of hetrazepine derivative PAF antagonists with anticholinergics, can be used for bronchial asthma research. Piperilate hydrochloride also causes hypotension and rescues mice poisoned by the organophosphates .
    Piperilate hydrochloride
  • HY-123816
    ONO 2050297

    		Leukotriene Receptor Inflammation/Immunology
    ONO 2050297 (Compound 19) is a selective Cysteinyl leukotriene (CysLT) antagonist with IC50s of 17  and 0.87 nM for CysLT1 and CysLT2, respectively. ONO 2050297 can be used for bronchial asthma research .
    ONO 2050297
  • HY-105594
    Nivimedone

    BRL 10833 free base

    		 Histamine Receptor Inflammation/Immunology
    Nivimedone (BRL 10833 free base) is an orally active antiallergic agent. Nivimedone inhibits IgE-mediated passive cutaneous anaphylaxis in rats. Nivimedone suppresses antigen-induced histamine release from lung tissues passively sensitized with atopic serum. Nivimedone can be used in research related to bronchial asthma .
    Nivimedone
  • HY-16768R
    Fevipiprant (Standard)

    QAW039 (Standard); NVP-QAW039 (Standard)

    		 Prostaglandin Receptor Reference Standards Cardiovascular Disease
    Fevipiprant (Standard) is the analytical standard of Fevipiprant. This product is intended for research and analytical applications. Fevipiprant (QAW039, NVP-QAW039) is s an orally active, selective, reversible prostaglandin D2 (DP2) receptor antagonist with an Kd value of 1.14 nM. Fevipiprant has the potential for the research of bronchial asthma .
    Fevipiprant (Standard)
  • HY-182414
    NCO-650 free base

    		Ser/Thr Protease Inflammation/Immunology
    NCO-650 free base is an antiallergic agent that acts by inhibiting tryptase, a key trypsin-like protease in mast cells. NCO-650 free base inhibits mast cell histamine release, increases intracellular cAMP levels in mast cells, suppresses bronchoconstriction, and prevents decreases in perfusion pressure and systemic blood pressure. NCO-650 free base is applicable to the research of allergic diseases and bronchial asthma .
    NCO-650 free base
  • HY-180376
    TAC 363

    		Neurokinin Receptor Inflammation/Immunology
    TAC 363 is a selective tachykinin NK-2 receptor antagonist. TAC 363 shows a rightward shift in the contractile response curve induced by Neurokinin A (HY-P0197) with a pA2 of 9.82. TAC 363 has a weak antagonistic effect on NK-1 receptors. TAC 363 can inhibit Neurokinin A-induced bronchoconstriction in guinea pigs with an ED50 of 0.3 mg/kg. TAC 363 can be used for the research of bronchial asthma .
    TAC 363
  • HY-A0075R
    Decloxizine dihydrochloride (Standard)

    UCB 1402 dihydrochloride (Standard); NSC289116 dihydrochloride (Standard)

    		 Reference Standards Histamine Receptor 5-HT Receptor Metabolic Disease Inflammation/Immunology
    Decloxizine (UCB-1402; NSC289116) dihydrochloride (Standard) is the analytical standard of Decloxizine dihydrochloride. This product is intended for research and analytical applications. Decloxizine dihydrochloride is an orally active bronchodilator that can penetrate the blood-brain barrier. Decloxizine dihydrochloride is a piperazine-type H1 histamine receptor antagonist. Decloxizine dihydrochloride selectively blocks H1 histamine receptors, inhibiting histamine-induced capillary dilation, edema, and itching. Decloxizine dihydrochloride has some 5-HT2 receptor antagonistic activity. Decloxizine dihydrochloride can be used in studies of urticaria, allergic rhinitis, and bronchial asthma.
    Decloxizine dihydrochloride (Standard)

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