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ethanol+extract

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By Targets:	Acyltransferase (1) Bacterial (1) Biochemical Assay Reagents (1) COX (1) EBV (1) Fungal (1) HSV (1) Influenza Virus (1) Lipase (1) NF-κB (1) NO Synthase (2) Quinone Reductase (1) Tie (1) VEGFR (1)
By Research Areas:	Cancer (4) Cardiovascular Disease (2) Infection (4) Inflammation/Immunology (1) Metabolic Disease (1) Neurological Disease (1)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N4193

Glabrol 3 Publications Verification	Acyltransferase	Cardiovascular Disease
Glabrol (Compound 1), One isoprenyl flavonoid was isolated from ethanol extract of licorice roots, is a potent and non-competitive Acyl-coenzyme A: cholesterol acyltransferase (ACAT) inhibitor with an IC₅₀ value of 24.6 μM for rat liver microsomal ACAT activity .

HY-N11985

Ophiopogonone C	Others	Others
Ophiopogonone C (compound 3) is an isoflavone compound isolated from the ethanol extract of Ophiopogon japonicus tubers .

HY-N9588

Pedaliin	Others	Cancer
Pedaliin is a bioactive component obtained from the ethanol extract of Sesame (Sesamum indicum L.) leaves (SLs). Pedaliin shows in vitro antioxidant and anti-colon cancer efficacy with radical scavenging activity and ferric reducing antioxidant power (FRAP) .

HY-N3344

Macrocarpal C	Fungal	Others
Macrocarpal C can be isolated from the 95 % ethanol extract of fresh leaves of E. globulus. Macrocarpal C inhibits the growth of T. mentagrophytes via an increase in the permeability of the fungal membrane. Macrocarpal C increases the production of intracellular ROS and? induces apoptosis as a consequence of DNA fragmentation .

HY-N11009

11-Oxomogroside II A1	EBV	Infection
11-Oxomogroside II A1 (compound 7) is an oxidized cucurbitin. It can be isolated from the ethanol extract of Rohanberry fruit. 11-Oxomogroside II A1 inhibits the activation of Epstein-Barr virus (EBV) early antigen (EBV-EA) induced by 12-O-tetradecanoylphorbol-13-acetate (TPA). 11-Oxomogroside II A1 also weakly inhibits the activation of (±)-(E)-methyl-2-[(E)-hydroxyimino]-5-nitro-6-methoxy-3-hexemide (NOR 1), a nitric oxide (NO) donor .

HY-N12359

Mulberrofuran B	Others	Others
Mulberrofuran B can be isolated from the Ethanol extract of Morus alba. Mulberrofuran B has antioxidant activity .

HY-123080

Tanshinol B	Others	Others
Tanshinol B is a bioactive component of Salvia miltiorrhiza, which can be isolated from the 50% ethanol extract of the roots and rhizomes of Seaweed prowazekii .

HY-N8262

Dehydrocorybulbine chloride	Influenza Virus	Infection
Dehydrocorybulbine chloride is an isoquinoline alkaloid with neuraminidase (NA) inhibitory activity. Dehydrocorybulbine chloride can be isolated from the 95% ethanol extract of the rhizome of Viola odorata .

HY-N3882

Eurycarpin A	Others	Others
Eurycarpin A is isoflavonoid analog isolated from the ethanol extract of the Chinese folk medicine Crotalaria ferruginea .

HY-N11021

Feruloyl tyramine	Others	Others
Feruloyl tyramine, an amide compound, can be isolated from ethanol extract of hemp seed. Feruloyl tyramine injected into the lateral ventricle caused hypothermia and dyskinesia in mice .

HY-N10864

Imbricataflavone A	Others	Others
Imbricataflavone A, a imbricataflavone, can be isolated from 70% ethanol extract of C. chinensis .

HY-N1558

Pterisolic acid A	Others	Others
Pterisolic acid A can be isolated from the ethanol extract of the fern Pteris semipinnata (Pteridaceae) .

HY-N1562

Pterisolic acid F	Others	Others
Pterisolic acid F can be isolated from the ethanol extract of the fern Pteris semipinnata (Pteridaceae) .

HY-N15696

Lagesianine A	Biochemical Assay Reagents	Others
Lagesianine A (Compound 9) can be obtained from ethanol extracts of the leaves of Aristolochia lagesiana var. intermedia and analyzed by spectrometric methods .

HY-N2749

7-Hydroxy-5,8-dimethoxyflavanone	Others	Others
7-Hydroxy-5,8-dimethoxyflavanone is a compound isolated from the ethanol extract of the whole plants of Sarcandra hainanensis .

HY-N1496

15,16-Di-O-acetyldarutoside	Others	Others
15,16-Di-O-acetyldarutoside (compound 5) is an ent-pimarane diterpenoid compound isolated from the ethanol extract of Siegesbeckia orientalis .

HY-N1035

Urs-12-ene-3β,16β,22α-triol	Others	Others
Urs-12-ene-3β,16β,22α-triol is a terpenoid compound isolated from the ethanol extract of fresh aerial parts of the Patagonian shrub Nardophyllum bryoides .

HY-N8989

(1,5E,11E)-Tridecatriene-7,9-diyne-3,4-diacetate	Lipase	Metabolic Disease
(1,5E,11E)-Tridecatriene-7,9-diyne-3,4-diacetate, isolated from the ethanol extract of Atractylodes lancea rhizome, displays significant lipase inhibition with an IC₅₀ value of 23.9 µg/mL. Antiobesity Effect .

HY-N11137

3′-Omethyl-5′-hydroxydiplacone	Bacterial	Infection
3′-Omethyl-5′-hydroxydiplacone (compound 2), an C-6-geranylflavonoid, can be isolated from the ethanol extract of Paulownia tomentosa fruits. 3′-Omethyl-5′-hydroxydiplacone has antibacterial activity against Gram-positive bacteria .

HY-N13218

Pueraria Extract	Others	Cardiovascular Disease
Pueraria Extract is a kudzu extract, and its components include: Isoflavones. Pueraria Extract (ethanol extract) can significantly improve cardiac damage in rats with acute myocardial infarction. Pueraria Extract improves bile acid levels by increasing the expression of CYP7A1 and restoring the diversity of intestinal microbiota. Pueraria Extract can also inhibit the FXR-FGF15 signaling pathway and increase the expression of OST-α to increase bile acid reabsorption and fecal excretion. .

HY-N13702

Secoaristolenedioic acid	Others	Others
Secoaristolenedioic acid (Compound 1) is a sesquiterpene, which is found in ethanol extract of the roots and rhizomes of Nardostachys chinensis .

HY-N1603

16-o-Acetyldarutigenol	Others	Others
16-o-Acetyldarutigenol (compound 4) is an ent-pimarane diterpenoid compound isolated from the ethanol extract of Siegesbeckia orientalis .

HY-N18293

Makisterone A 2-acetate	HSV	Infection
Makisterone A 2-acetate is a steroid compound that can be isolated from the 75% ethanol extract of Cyanotis arachnoidea. Experimental tests show that Makisterone A 2-acetate has no anti-HSV-1 activity .

HY-N2809

Acantrifoside E	Others	Others
Acantrifoside E (Compound 8) is a nature compound. Acantrifoside E can be isolated from the 90% ethanol extract of Salacia cochinchinensis. Acantrifoside E has none α-glucosidase inhibitory activity .

HY-W749400

1,3-Diacetyl-2-imidazolidinone	Others	Others
1,3-Diacetyl-2-imidazolidinone is an imidazolidinone derivative. 1,3-Diacetyl-2-imidazolidinone can be found in the benzene/ethanol extractives of Eucalyptus urophylla leaves .

HY-N9885

Xuedanencins D	Others	Cancer
Xuedanencins D is a cucurbitane-type triterpenoid natural product without significant cytotoxicity against human cervical cancer HeLa cells (IC₅₀ >100 μM). Xuedanencins D can be naturally extracted from the 95% ethanol extract of the tubers of Hemsleya penxianensis (a plant of the Hemsleya genus in the Cucurbitaceae family) .

HY-N9878

Pistaciamide	Others	Neurological Disease
Pistaciamide is an N-phenyl-pyrrolidone derivative, and its related pyrrolidone derivatives are commonly used in the treatment of neurological disorders, making it relevant for research of neurological dysfunction. Pistaciamide can be naturally extracted from the 90% ethanol extract of fresh shoots and inflorescences of Pistacia chinensis Bunge. (a plant of the Anacardiaceae family) .

HY-N9765

threo-Guaiacylglycerol β-coniferyl ether	NF-κB NO Synthase Quinone Reductase COX	Others
threo-Guaiacylglycerol β-coniferyl ether (compound 9) is a potentially active compound, but its inhibitory activity against NF-κB, nitric oxide production, aromatase, quinone reductase 2, and cyclooxygenase (COX-1/-2) is not significant. threo-Guaiacylglycerol β-coniferyl ether can be naturally extracted from the 95% ethanol extract of the whole plant of Lepisorus contortus (Christ) Ching (a plant of the Polypodiaceae family) .

HY-117733

Zerumin A	Tie VEGFR	Cancer
Zerumin A is an anti-angiogenic agent that acts on multiple molecular targets related to angiogenesis (including kdr/VEGFR2, angpt1, angpt2, tie1, and tie2). Zerumin A specifically inhibits the proliferation and migration of human umbilical vein endothelial cells (HUVECs) by regulating the VEGF-VEGFR and ANGPT-TIE signaling pathways, and dose-dependently inhibits angiogenesis (10-20 μM significantly inhibits zebrafish embryo angiogenesis). Zerumin A can be used in the research of cancer and angiogenesis-related inflammatory diseases. Zerumin A can be naturally extracted from the 95% ethanol extract of the fruits, seeds, and pericarp of Alpinia caerulea (R.Br.) Bentham (a plant of the Alpinia genus in the Zingiberaceae family) .

HY-N13821

2α-Acetoxy-14,15-cyclopimara-7β,16-diol	NO Synthase	Inflammation/Immunology
2α-Acetoxy-14,15-cyclopimara-7β,16-diol (compound 2) is a potential anti-inflammatory agent, exhibiting weak anti-inflammatory activity by inhibiting inflammation-related NO production. 2α-Acetoxy-14,15-cyclopimara-7β,16-diol only inhibits nitric oxide (NO) production in LPS-induced RAW264.7 macrophages, with an inhibition rate of 28.1%. 2α-Acetoxy-14,15-cyclopimara-7β,16-diol can be naturally extracted from the 70% ethanol extract of the seeds of Caesalpinia minax Hance (a plant of the Caesalpinia genus in the Fabaceae family) .

Cat. No.	Product Name	Target	Research Area	Image

HY-N9415

Sitoindoside II	Inhibitory Antibodies	Cancer
Sitoindoside II is a chemopreventive agent that induces HL-60 cell differentiation (ED₅₀: 69 nM). Sitoindoside II can be isolated from the ethanol extract of whole plants of Munronia delavayi .

Glabrol 3 Publications Verification	Cardiovascular Disease Flavonoids Classification of Application Fields Leguminosae Flavonones Phenols Polyphenols Plants Glycyrrhiza uralensis Fisch. Disease Research Fields Source Classification	Acyltransferase
Glabrol (Compound 1), One isoprenyl flavonoid was isolated from ethanol extract of licorice roots, is a potent and non-competitive Acyl-coenzyme A: cholesterol acyltransferase (ACAT) inhibitor with an IC₅₀ value of 24.6 μM for rat liver microsomal ACAT activity .

Ophiopogonone C	Ophiopogon japonicus (L. f.) Ker-Gawl. Flavonoids Liliaceae Plants Other Flavonoids Source Classification	Others
Ophiopogonone C (compound 3) is an isoflavone compound isolated from the ethanol extract of Ophiopogon japonicus tubers .

Pedaliin	Structural Classification Flavonoids Sesamum indicum Linn. Pedaliaceae Plants Isoflavones	Others
Pedaliin is a bioactive component obtained from the ethanol extract of Sesame (Sesamum indicum L.) leaves (SLs). Pedaliin shows in vitro antioxidant and anti-colon cancer efficacy with radical scavenging activity and ferric reducing antioxidant power (FRAP) .

Macrocarpal C	Phenols Polyphenols Myrtaceae Plants Eucalyptus globulus Labill. Source Classification	Fungal
Macrocarpal C can be isolated from the 95 % ethanol extract of fresh leaves of E. globulus. Macrocarpal C inhibits the growth of T. mentagrophytes via an increase in the permeability of the fungal membrane. Macrocarpal C increases the production of intracellular ROS and? induces apoptosis as a consequence of DNA fragmentation .

11-Oxomogroside II A1	Triterpenes Terpenoids Cucurbitaceae Siraitia grosvenorii (Swingle) C. Jeffrey ex Lu et Z. Y. Zhang Plants Source Classification	EBV
11-Oxomogroside II A1 (compound 7) is an oxidized cucurbitin. It can be isolated from the ethanol extract of Rohanberry fruit. 11-Oxomogroside II A1 inhibits the activation of Epstein-Barr virus (EBV) early antigen (EBV-EA) induced by 12-O-tetradecanoylphorbol-13-acetate (TPA). 11-Oxomogroside II A1 also weakly inhibits the activation of (±)-(E)-methyl-2-[(E)-hydroxyimino]-5-nitro-6-methoxy-3-hexemide (NOR 1), a nitric oxide (NO) donor .

Mulberrofuran B	Phenols Polyphenols Morus alba L. Plants Moraceae Source Classification	Others
Mulberrofuran B can be isolated from the Ethanol extract of Morus alba. Mulberrofuran B has antioxidant activity .

Tanshinol B	Quinones Labiatae Plants Naphthalene Quinones Apuleia leiocarpa (Vogel) J.F.Macbr. Source Classification	Others
Tanshinol B is a bioactive component of Salvia miltiorrhiza, which can be isolated from the 50% ethanol extract of the roots and rhizomes of Seaweed prowazekii .

Dehydrocorybulbine chloride	Alkaloids Other Alkaloids Plants Papaveraceae Corydalis turtschaninovii Bess. Source Classification	Influenza Virus
Dehydrocorybulbine chloride is an isoquinoline alkaloid with neuraminidase (NA) inhibitory activity. Dehydrocorybulbine chloride can be isolated from the 95% ethanol extract of the rhizome of Viola odorata .

Eurycarpin A	Flavonoids Plants Crotalaria ferruginea Grah. ex Benth. Isoflavones Source Classification Fabaceae	Others
Eurycarpin A is isoflavonoid analog isolated from the ethanol extract of the Chinese folk medicine Crotalaria ferruginea .

Feruloyl tyramine	Alkaloids Cannabis sativa L Phenols Plants Moraceae Source Classification	Others
Feruloyl tyramine, an amide compound, can be isolated from ethanol extract of hemp seed. Feruloyl tyramine injected into the lateral ventricle caused hypothermia and dyskinesia in mice .

Imbricataflavone A	Flavonoids Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring Source Classification	Others
Imbricataflavone A, a imbricataflavone, can be isolated from 70% ethanol extract of C. chinensis .

Pterisolic acid A	Terpenoids Pteridaceae Diterpenoids Pteris semipinnata L. Sp. Plants Source Classification	Others
Pterisolic acid A can be isolated from the ethanol extract of the fern Pteris semipinnata (Pteridaceae) .

Pterisolic acid F	Terpenoids Pteridaceae Diterpenoids Pteris semipinnata L. Sp. Plants Source Classification	Others
Pterisolic acid F can be isolated from the ethanol extract of the fern Pteris semipinnata (Pteridaceae) .

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ethanol+extract

Inhibitors & Agonists

Inhibitory Antibodies

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Natural
Products