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glycopeptides

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-A0097
    Teicoplanin
    1 Publications Verification

    Antibiotic MDL-507; MDL-507

    		 Bacterial Antibiotic Infection
    Teicoplanin is a glycopeptide antibiotic indicated for use in serious infections caused by Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus and Enterococcus aureus.Teicoplanin shows antiviral activity for HIV-1, SARS-CoV1 and SARS-CoV2. Teicoplanin sodium shows anti-MRSA activity .
    Teicoplanin
  • HY-N10470
    Bleomycin A5
    1 Publications Verification

    Pingyangmycin

    		 Antibiotic DNA/RNA Synthesis Apoptosis Dynamin PINK1/Parkin Mitophagy Infection Cancer
    Bleomycin A5 (Pingyangmycin) is a glycopeptide antibiotic with multiple biological activities, which can be isolated from Streptomyces. Bleomycin A5 exerts cytotoxic effects by binding to Fe 2+ to form a complex, inducing single-strand and double-strand DNA breaks, and inhibiting DNA replication. Bleomycin A5 inhibits Drp1-mediated mitochondrial fission and suppresses PINK1/Parkin pathway-mediated mitophagy, ultimately triggering mitochondria-mediated cellular apoptosis. Bleomycin A5 can be used in cancer research .
    Bleomycin A5
  • HY-126490
    Phleomycin
    2 Publications Verification

    		 Bacterial Antibiotic DNA/RNA Synthesis Infection Cancer
    Phleomycin is a copper-dependent DNA damaging agent and antibiotic with antitumor activity. Phleomycin binds to DNA and produces ROS in the presence of reducing agents (such as dithiothreitol and glutathione), inducing single-strand and double-strand breaks in DNA. Phleomycin can induce cell apoptosis or mutation and is widely used in cancer inhibition, microbial genetic transformation (as a screening marker to improve fungal transformation efficiency) and DNA repair mechanism research .
    Phleomycin
  • HY-B1831A
    Oritavancin diphosphate
    2 Publications Verification

    LY333328 diphosphate

    		 Bacterial Antibiotic Infection Inflammation/Immunology
    Oritavancin diphosphate (LY333328 diphosphate), a semisynthetic derivative of Vancomycin (HY-B0671), is an orally active glycopeptide antibiotic with bactericidal activity against gram-positive organisms. Oritavancin diphosphate shows antibacterial effect against B. anthracis, such as Ames strain with a MIC value of 0.015 g/mL. Oritavancin diphosphate inhibits cell wall synthesis and disrupts the membrane potential. Oritavancin diphosphate inhibits ArlS kinase activity thereby interfering the signal transduction. Oritavancin diphosphate enters cells by adsorptive endocytosis, which drives it to lysosomes, where it exerts antibiotic activity .
    Oritavancin diphosphate
  • HY-E70097
    Sialidase (α2-3-6-8-9)

    		Endogenous Metabolite Others
    Sialidase (α2-3-6-8-9) is a broadly specific sialidase that cuts linear and branched non-reducing terminal sialic acid residues from glycoproteins, glycopeptides, and oligosaccharides. Sialidase (α2-3-6-8-9) can be used for in vitro and in vivo polysaccharide analysis and characterization as well as complete glycoprotein remodeling .
    Sialidase (α2-3-6-8-9)
  • HY-108345
    Bleomycin

    		Antibiotic Cancer
    Bleomycin is a glycopeptide antibiotic. Bleomycin has potent antitumour activities against a range of lymphomas, head and neck cancers and germ-cell tumours. Bleomycin can be used for the research of cancer and chemotherapy .
    Bleomycin
  • HY-E70133
    Endo-β-N-acetylglucosaminidase F2

    Endo F2

    		 Others Metabolic Disease
    Endo-β-N-acetylglucosaminidase F2 (Endo F2), a highly specific endoglycosidase, cleaves within the chitobiose core of asparagine-linked complex biantennary and high mannose oligosaccharides from glycoproteins and glycopeptides. Endo F2 cleaves biantennary glycans at a rate approximately 20 times greater than high mannose glycans. The activity of Endo F2 is identical on biantennary structures with and without core fucosylation. Endo F2 is not active on hybrid or tri- and tetra-antennary oligosaccharides .
    Endo-β-N-acetylglucosaminidase F2
  • HY-138053
    Ristocetin A sulfate

    Ristomycin III

    		 Antibiotic Cardiovascular Disease Infection
    Ristocetin A sulfate (Ristomycin III) is a glycopeptide antibiotic that binds to von Willebrand factor (VWF) and bacterial cell wall components. Ristocetin A sulfate interferes with the biosynthesis of bacterial peptidoglycan by inhibiting transpeptidation. As an inducer of platelet adhesion and aggregation, Ristocetin A sulfate drives conformational changes by binding to the A1 domain of VWF, thereby activating downstream signaling pathways and promoting cytoskeletal rearrangement. Ristocetin A sulfate not only enhances platelet adhesion and spreading on immobilized VWF, but also induces the formation of asymmetric dimers with anticooperativity between platelets and plasma VWF. Ristocetin A sulfate is widely used in studies related to thromboembolic diseases and bacterial infections .
    Ristocetin A sulfate
  • HY-111428
    Phleomycin D1
    2 Publications Verification

    PLM D1

    		 Antibiotic Infection
    Phleomycin D1 (PLM D1), a glycopeptide antibiotic, is a member of the Bleomycin/Phleomycin family. Phleomycin D1 causes cell death by binding and cleaving DNA. Phleomycin D1 induces cell cycle arrest at S phase .
    Phleomycin D1
  • HY-138560
    Cross-linked dextran G 50
    2 Publications Verification

    		 Biochemical Assay Reagents Others
    Cross-linked dextran G 50 is a gel filtration medium. Cross-linked dextran G 50 can be used in gel permeation chromatography for fractionation of the glycopeptide mixture (Sphere protein separation range: 1.5K-30K Da; Polysaccharide separation range: 500-10K Da) .
    Cross-linked dextran G 50
  • HY-E70555
    PNGase A

    		Glycosidase Others
    PNGase A is a β-aspartylglucosaminidase and N-glycan-releasing enzyme. PNGase A catalyzes hydrolysis reactions to release the N-glycan moiety from glycoproteins or glycopeptides. PNGase A releases N-linked oligosaccharides containing core α-1,3 fucose from glycopeptides. PNGase A undergoes self-deglycosylation, which may cause contamination of endogenous glycan structures in N-glycan analysis. PNGase A cannot be heterologously expressed in recombinant expression systems; it can be extracted and purified from almond seeds .
    PNGase A
  • HY-P0066
    Contulakin G

    		Neurotensin Receptor Neurological Disease
    Contulakin G is an O-glycosylated invertebrate neurotensin. Contulakin-G is a weaker agonist for the neurotensin receptor. Contulakin G is also a potent antinociceptive agent .
    Contulakin G
  • HY-P3302
    Sialylglycopeptide

    		Bacterial Infection
    Sialylglycopeptide is an orally active glycopeptide found in egg yolk. Sialylglycopeptide inhibits the binding of Salmonella enteritidis and Escherichia coli to intestinal cells, and protects mice from Salmonella infection. Sialylglycopeptide can be used in the research of Salmonella infection .
    Sialylglycopeptide
  • HY-148390
    Sialylglyco peptide

    		Drug Derivative Others
    Sialylglyco peptide is a N-Glycan and sialate glycopeptide .
    Sialylglyco peptide
  • HY-107833
    A40926

    		Antibiotic Bacterial Infection
    A40926 is a glycopeptide antibiotic that targets the bacterial cell wall peptidoglycan precursor D-alanyl-D-alanine (D-Ala-D-Ala). A40926 irreversibly inhibits cell wall synthesis by competitively binding to this target, and has high bactericidal activity against Gram-positive bacteria (such as Staphylococcus, Streptococcus) and Neisseria gonorrhoeae, with MIC=0.06-2 μg/mL, and is also effective against penicillin-resistant strains. A40926 blocks peptidoglycan cross-linking, destroys cell wall integrity, and causes bacterial lysis and death. A40926 has a fat-soluble fatty acid structure, which can increase serum concentrations and prolong the duration of action (e.g., the terminal half-life in rats is 61.22 h) .
    A40926
  • HY-125918
    Bleomycin A5 hydrochloride

    Pingyangmycin hydrochloride

    		 Antibiotic DNA/RNA Synthesis Apoptosis Dynamin PINK1/Parkin Mitophagy Infection Cancer
    Bleomycin A5 (Pingyangmycin) hydrochloride is a glycopeptide antibiotic with multiple biological activities, which can be isolated from Streptomyces. Bleomycin A5 hydrochloride exerts cytotoxic effects by binding to Fe 2+ to form a complex, inducing single-strand and double-strand DNA breaks, and inhibiting DNA replication. Bleomycin A5 hydrochloride inhibits Drp1-mediated mitochondrial fission and suppresses PINK1/Parkin pathway-mediated mitophagy, ultimately triggering mitochondria-mediated cellular apoptosis. Bleomycin A5 hydrochloride can be used in cancer research .
    Bleomycin A5 hydrochloride
  • HY-N13150A
    Norvancomycin hydrochloride

    N-Demethylvancomycin hydrochloride; NVCM hydrochloride

    		 Antibiotic Bacterial Infection
    Norvancomycin hydrochloride is a glycopeptide antibiotic which can be found in Nocardia orientalis and active against several strains of S. aureus and S. epidermidis. Norvancomycin hydrochloride can be used for infection research .
    Norvancomycin hydrochloride
  • HY-16304
    Mannose 1-phosphate

    		Endogenous Metabolite Metabolic Disease
    Mannose 1-phosphate is a phosphorylated mannose that serves as a precursor of GDP-mannose, a constituent unit of glycosylation biosynthetic pathways. Mannose 1-phosphate increases intracellular GDP-mannose concentration, promotes normalization of lipid-linked oligosaccharide structures, and enhances the formation of mature N-glycans on cellular proteins. Mannose 1-phosphate can be used in studies related to glycosylation disorders .
    Mannose 1-phosphate
  • HY-148393
    G0 N-glycan-Asn

    		Biochemical Assay Reagents Others
    G0 N-glycan-Asn is a glycopeptide. G0 N-glycan-Asn can be used for various biochemical studies .
    G0 N-glycan-Asn
  • HY-E70070
    Endo-β-N-acetylglucosaminidase (Endo A)

    		Bacterial Others
    Endo-β-N-acetylglucosaminidase (Endo A) is an Endo-β-N-acetylglucosaminidases (ENGases) from Arthrobacter protophormiae. Endo-β-N-acetylglucosaminidase (Endo A) can transfer a high-mannose type oligosaccharide to monosaccharides such as N-acetylglucosamine (GlcNAc) and glucose to form a new oligosaccharide. Endo-β-N-acetylglucosaminidase (Endo A) catalyzes glycopeptide synthesis by using Man3GlcNAc-oxazoline .
    Endo-β-N-acetylglucosaminidase (Endo A)
  • HY-P2929B
    PNGase F (Immobilized, Microspin)

    		Glycosidase Others
    PNGase F (Immobilized, Microspin) is a resin in which PNGase F (peptide N-glycosidase F) is covalently coupled to agarose beads, and it is used to remove N-glycans from antibodies, fusion proteins and other N-glycosylated proteins. The enzyme is recombinantly expressed in Escherichia coli, with its sequence derived from Flavobacterium meningsepticum .
    PNGase F (Immobilized, Microspin)
  • HY-E70879
    Endoglycosidase M (N175Q mutant)

    EndoM N175Q

    		 Glycosidase Others
    Endoglycosidase M (N175Q mutant) (EndoM N175Q) can transfer natural N-glycans or oxazoline N-glycans to any peptide or protein with a GlcNAc residue to form a β1-4-glycosidic linkage. Endoglycosidase M (N175Q mutant) is a useful tool in the synthesis of homogeneous glycopeptides and glycoproteins .
    Endoglycosidase M (N175Q mutant)
  • HY-E70054
    beta-1,3-Galactosyltransferase (WbgO)

    		Others Others
    beta-1,3-Galactosyltransferase (WbgO) (CgtB) acts on N-glycan substrates. beta-1,3-Galactosyltransferase (WbgO) catalyzes the formation of type 1 chains on oligosaccharide, glycopeptide, and glycoprotein substrates, including itself .
    beta-1,3-Galactosyltransferase (WbgO)
  • HY-P5309
    IgA1 Peptide GN5

    		Biochemical Assay Reagents Inflammation/Immunology
    IgA1 Peptide GN5 is a synthetic glycopeptide and can be used for detection of gender difference and epitope specificity of IgG antibody activity against IgA1 hinge portion in IgA nephropathy patients .
    IgA1 Peptide GN5
  • HY-W039917
    2-Azido-2-deoxy-D-galactose, 98%

    		Biochemical Assay Reagents Others
    2-Azido-2-deoxy-D-galactose, 98% can be applied in glycobiology, can be glycosylated by glycopeptides, and can be used for the synthesis of glycoconjugates.
    2-Azido-2-deoxy-D-galactose, 98%
  • HY-P10701
    Q11 peptide

    		Biochemical Assay Reagents Inflammation/Immunology Cancer
    Q11 peptide is a β-sheet-forming peptide that plays an important role in self-assembly and targeted applications. As a scaffold peptide, Q11 peptide can display immunogenic epitopes and is widely used in peptide-based immune vaccine research. Additionally, Q11 peptide can be conjugated with MUC1 glycopeptides for the study of self-assembling, adjuvant-free MUC1 glycopeptide vaccines. Q11 peptide holds great potential for research in the field of cancer immunology .
    Q11 peptide
  • HY-105282
    Eremomycin

    MM 45289; A 82846A

    		 Antibiotic Bacterial Infection
    Eremomycin (MM 45289) is a potent glycopeptide antibiotic closely related to Vancomycin (HY-B0671). Eremomycin shows antibacterial activity in Staphylococcus spp. and Bacillus subtilis ATCC6633, with the MIC values of 0.03-1.6 μg/mL .
    Eremomycin
  • HY-130613
    MAC-545496

    		Bacterial Infection
    MAC-545496 is a nanomolar inhibitor of glycopeptide-resistance-associated protein R (GraR). MAC-545496 displays strong binding affinity to the full-length GraR protein (Kd ≤ 0.1 nM). MAC-545496 is an antivirulence agent that reverses β-lactam resistance in Methicillin-resistant strains (MRSA) .
    MAC-545496
  • HY-B1831
    Oritavancin

    LY 333328; Orbactiv

    		 Antibiotic Bacterial Infection Inflammation/Immunology
    Oritavancin (LY 333328), a semisynthetic derivative of Vancomycin (HY-B0671), is an orally active glycopeptide antibiotic with bactericidal activity against gram-positive organisms. Oritavancin shows antibacterial effect against B. anthracis, such as Ames strain with a MIC value of 0.015 g/mL. Oritavancin inhibits cell wall synthesis and disrupts the membrane potential. Oritavancin inhibits ArlS kinase activity thereby interfering the signal transduction. Oritavancin enters cells by adsorptive endocytosis, which drives it to lysosomes, where it exerts antibiotic activity .
    Oritavancin
  • HY-N13150
    Norvancomycin

    N-Demethylvancomycin; NVCM

    		 Antibiotic Bacterial Infection
    N-Demethylvancomycin is a glycopeptide antibiotic which can be extracted from Nocardia orientalis and active against several strains of S. aureus and S. epidermidis. N-Demethylvancomycin can be used for infection research .
    Norvancomycin
  • HY-P5309A
    IgA1 Peptide GN5 TFA

    		Biochemical Assay Reagents Inflammation/Immunology
    IgA1 Peptide GN5 (TFA) is a synthetic glycopeptide and can be used for detection of gender difference and epitope specificity of IgG antibody activity against IgA1 hinge portion in IgA nephropathy patients .
    IgA1 Peptide GN5 TFA
  • HY-130337
    Teicoplanin A2-2

    		Antibiotic Bacterial Infection
    Teicoplanin A2-2 is a glycopeptide antibiotic. Teicoplanin A2-2 exhibits antibacterial activity, particularly against coagulase-negative staphylococci (CNS). Teicoplanin A2-2 inhibits bacterial cell wall synthesis by competitively binding to the terminal D-Ala-D-Ala peptide bonds in the cell wall synthesis process, leading to bacterial death. Teicoplanin A2-2 can be used for research into bacterial resistance mechanisms and the development of new antibiotics .
    Teicoplanin A2-2
  • HY-148209
    Balhimycin

    		Antibiotic Bacterial Infection
    Balhimycin is a glycopeptide antibiotic, found from the fermentation broth of a Amycolatopsis sp. Balhimycin shows anti-bacterial activity against staphylococci and anaerobes .
    Balhimycin
  • HY-100997R
    Chloroorienticin A (Standard)

    A82846B (Standard); LY 264826 (Standard); PA 45052A (Standard)

    		 Reference Standards Antibiotic Bacterial Infection
    Chloroorienticin A (Standard) is the analytical standard of Chloroorienticin A (HY-100997). This product is intended for research and analytical applications. Chloroorienticin A (A82846B) is a glycopeptide antibiotic. Chloroorienticin A exhibits excellent activity against staphylococci and streptococci .
    Chloroorienticin A (Standard)
  • HY-E70159
    Fucosyltransferase 11

    EC:2.4.1.-; FUT11

    		 Glycosyltransferase Cancer
    Fucosyltransferase 11 (EC:2.4.1.-, FUT11) links alpha-l-fucose onto conalbumin glycopeptides and biantennary N-glycan acceptors. Fucosyltransferase 11 plays an important role in cancer .
    Fucosyltransferase 11
  • HY-A0097A
    Teicoplanin sodium

    Antibiotic MDL-507 sodium; MDL-507 sodium

    		 Antibiotic HIV SARS-CoV Infection
    Teicoplanin sodium is a glycopeptide antibiotic indicated for use in serious infections caused by Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus and Enterococcus aureus.Teicoplanin sodium shows antiviral activity for HIV-1, SARS-CoV1 and SARS-CoV2. Teicoplanin sodium shows anti-MRSA activity .
    Teicoplanin sodium
  • HY-E70375
    Fructosyl-peptide oxidase (FPOX-CE)

    Fructosyl-peptide: oxygen oxidoreductase

    		 Others Others
    Fructosyl-peptide oxidase (FPOX-CE) (Fructosyl-peptide: oxygen oxidoreductase) is an enzyme that catalyzes the oxidation of glycopeptides. Fructosyl-peptide oxidase (FPOX-CE) shows high activity against small molecule glycated peptides, but no activity is detected against the glycated hexapeptide standard fVHLTPE used in the study. Fructosyl-peptide oxidase (FPOX-CE) can be used in the study of diabetes monitoring .
    Fructosyl-peptide oxidase (FPOX-CE)
  • HY-138560A
    Cross-linked dextran G 50, medium

    		Biochemical Assay Reagents Others
    Cross-linked dextran G 50, medium is a gel filtration medium. Cross-linked dextran G 50, medium can be used in gel permeation chromatography for fractionation of the glycopeptide mixture (Sphere protein separation range: 1.5K-30K Da; Polysaccharide separation range: 500-10K Da). Cross-linked dextran G 50, medium are microspheres with an average particle size of D50 = 220-250 μm .
    Cross-linked dextran G 50, medium
  • HY-138560B
    Cross-linked dextran G 50, fine

    		Biochemical Assay Reagents Others
    Cross-linked dextran G 50, fine is a gel filtration medium. Cross-linked dextran G 50, fine can be used in gel permeation chromatography for fractionation of the glycopeptide mixture (Sphere protein separation range: 1.5K-30K Da; Polysaccharide separation range: 500-10K Da). Cross-linked dextran G 50, fineThe average particle size is D50=110-130 μmof microspheres .
    Cross-linked dextran G 50, fine
  • HY-W033728
    Platinum(COD)dichloride

    		Bacterial Infection
    Platinum(COD)dichloride (Compound Pt1) is an Antibacterial agent. Platinum(COD)dichloride shows antibacterial activity against a panel of gram-positive bacteria including Vancomycin (HY-B0671) and Methicillin (HY-121544) resistant Staphylococcus aureus .
    Platinum(COD)dichloride
  • HY-135520
    Trimannosyldilysine

    Man3Lys2

    		 Biochemical Assay Reagents Others
    Trimannosyldilysine (Man3Lys2) is a mannosyl glycopeptide that can be coupled to human placental p-glucocerebrosidase to enhance macrophage uptake .
    Trimannosyldilysine
  • HY-148392
    Neu5Gcα(2-6) N-Glycan-Asn

    		Biochemical Assay Reagents Others
    Neu5Gcα(2-6) N-Glycan-Asn is a glycopeptide. Neu5Gcα(2-6) N-Glycan-Asn can be used for various biochemical studies .
    Neu5Gcα(2-6) N-Glycan-Asn
  • HY-126800
    Glycotriosyl glutamine

    		Transmembrane Glycoprotein Drug Derivative Inflammation/Immunology
    Glycotriosyl glutamine is a synthetic analogue of the Glycopeptide. Glycotriosyl glutamine induces focal glomerulonephritis (FGN) and the appearance of myeloid bodies in the epithelial cells of the podocytes in rats with nephritogenic activity .
    Glycotriosyl glutamine
  • HY-100997
    Chloroorienticin A

    A82846B; LY 264826; PA 45052A

    		 Antibiotic Bacterial Infection
    Chloroorienticin A (A82846B) is a glycopeptide antibiotic. Chloroorienticin A exhibits excellent activity against staphylococci and streptococci .
    Chloroorienticin A
  • HY-N14416
    Parvodicin A

    		Antibiotic Bacterial Infection
    Parvodicin A is a glycopeptide antibiotic. Parvodicin A has inhibitory effect on Staphylococcus aureus, Staphylococcus furfur, Staphylococcus hemolyticus and Enterococcus faecalis .
    Parvodicin A
  • HY-138083
    Parvodicin C2

    		Bacterial Antibiotic Infection
    Parvodicin C2 is a glycopeptide antibiotic that can be isolated from parvosata. Parvodicin C2 has antibacterial activity .
    Parvodicin C2
  • HY-N5181
    Parvodicin C3

    		Antibiotic Bacterial Infection
    Parvodicin C3 is a glycopeptide antibiotic. Parvodicin C3 has inhibitory effect on Staphylococcus aureus, Staphylococcus furfur, Staphylococcus hemolyticus and Enterococcus faecalis .
    Parvodicin C3
  • HY-N15040
    Parvodicin C4

    		Antibiotic Bacterial Infection
    Parvodicin C4 is a glycopeptide antibiotic. Parvodicin C4 has inhibitory effect on Staphylococcus aureus, Staphylococcus furfur, Staphylococcus hemolyticus and Enterococcus faecalis .
    Parvodicin C4
  • HY-N14420
    Parvodicin B2

    		Antibiotic Bacterial Infection
    Parvodicin B2 is a glycopeptide antibiotic. Parvodicin B2 has inhibitory effect on Staphylococcus aureus, Staphylococcus furfur, Staphylococcus hemolyticus and Enterococcus faecalis. Parvodicin B2 acts by inhibiting the synthesis of bacterial cell wall .
    Parvodicin B2
  • HY-N14418
    Parvodicin B1

    		Antibiotic Bacterial Infection
    Parvodicin B1 is a glycopeptide antibiotic. Parvodicin B1 has inhibitory effect on Staphylococcus aureus, Staphylococcus furfur, Staphylococcus hemolyticus and Enterococcus faecalis. Parvodicin B1 acts by inhibiting the synthesis of bacterial cell wall .
    Parvodicin B1

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