(1,5-Cyclooctadiene)dimethylplatinum(II)

Cat. No.: HY-W034984: Data Sheet
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(1,5-Cyclooctadiene) dimethylplatinum (II) (Compound Pt3) is an Antibacterial agent. (1,5-Cyclooctadiene) dimethylplatinum (II) exhibits limited but selective activity against some Gram-positive Staphylococcus aureus strains, including methicillin-resistant Staphylococcus aureus (MRSA) and Glycopeptide-intermediate Staphylococcus aureus (GISA). (1,5-Cyclooctadiene) dimethylplatinum (II) shows no hemolytic activity.

For research use only. We do not sell to patients.

(1,5-Cyclooctadiene)dimethylplatinum(II) Chemical Structure

CAS No. : 12266-92-1

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Description	(1,5-Cyclooctadiene) dimethylplatinum (II) (Compound Pt3) is an Antibacterial agent. (1,5-Cyclooctadiene) dimethylplatinum (II) exhibits limited but selective activity against some Gram-positive Staphylococcus aureus strains, including methicillin-resistant Staphylococcus aureus (MRSA) and Glycopeptide-intermediate Staphylococcus aureus (GISA). (1,5-Cyclooctadiene) dimethylplatinum (II) shows no hemolytic activity^[1].
In Vitro	(1,5-Cyclooctadiene) dimethylplatinum (II) (with a CC₅₀ of 100 μM) exhibits no toxicity to HEK-293 cells and shows no hemolytic activity against red blood cells^[1]. (1,5-Cyclooctadiene) dimethylplatinum (II) exhibits limited but selective activity against some Staphylococcus aureus strains, with significantly higher activity against MRSA and NRS 17 GISA^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. (1,5-Cyclooctadiene)dimethylplatinum(II) Related Antibodies
Molecular Weight	333.34
Formula	C₁₂H₂₄Pt
CAS No.	12266-92-1
Appearance	Solid
SMILES	C[Pt](C)(C)C.C1=C\CC/C=C\CC/1
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	4°C, protect from light, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Purity & Documentation	Data Sheet (271 KB) SDS (252 KB) Handling Instructions (2659 KB)
References	[1]. Frei A, et al. Platinum Cyclooctadiene Complexes with Activity against Gram-positive Bacteria. ChemMedChem. 2021;16(20):3165-3171. [Content Brief]