(2,2'-Bipyridine)dichloroplatinum(II)
Based on 1 Customer Validation
(2,2'-Bipyridine) dichloroplatinum (II) is a Pt (II) analog of Cisplatin (HY-17394) that induces cytotoxic activity in lung cancer, prostate cancer and melanoma cells. (2,2'-Bipyridine) dichloroplatinum (II) can be used in research related to lung cancer, prostate cancer and melanoma.
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- CAS No.: 13965-31-6
- 화학식: C10H8Cl2N2Pt
- 분자량:422.17
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
(2,2'-Bipyridine) dichloroplatinum (II) (Compound 4) shows no significant cytotoxicity against A549 lung cancer cells after 1 h, with an EC50 greater than 100 μM[1].
(2,2'-Bipyridine) dichloroplatinum (II) (1 h) potently inhibits the viability of DU-145 prostate cancer cells, with an EC50 value of 50 μM[1].
(2,2'-Bipyridine) dichloroplatinum (II) (1 h) potently inhibits the survival of MDA-MB-435 melanoma cells, with an EC50 of 20 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 13965-31-6
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Appearance Solid
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분자량 422.17
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화학식 C10H8Cl2N2Pt
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SMILES
[Cl-][Pt+2]1([N]2=C(C3=[N]1C=CC=C3)C=CC=C2)[Cl-]
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(2,2'-Bipyridine)dichloroplatinum(II) Related Classifications
HY-W450898 Related Classifications
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