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Cat. No.: HY-W033728

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Platinum(COD)dichloride

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Based on 1 Customer Validation

Platinum(COD)dichloride (Compound Pt1) is an Antibacterial agent. Platinum(COD)dichloride shows antibacterial activity against a panel of gram-positive bacteria including Vancomycin (HY-B0671) and Methicillin (HY-121544) resistant Staphylococcus aureus.

For research use only. We do not sell to patients.

CAS No.: 12080-32-9
Formula: C₈H₁₂Cl₂Pt
Molecular Weight:374.17

Storage:

4°C, protect from light, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Data Sheet (270 KB)

Platinum(COD)dichloride Chemical Structure

CAS No.: 12080-32-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vitro

Platinum(COD)dichloride (Compound Pt1) displays broad antibacterial activity against Gram-positive bacteria including MRSA, GISA, and VRSA, with an MIC₅₀ of 0.39 μM against S. aureus ATCC 43300 (MRSA)^[1].
Platinum(COD)dichloride (Compound Pt1) (up to 100 μM) is non-cytotoxic to HEK-293 cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Platinum(COD)dichloride (0.4 mM; injection) does not reduce MRSA bacterial load in infected Galleria mellonella larvae at the tested dose^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 12080-32-9
Appearance Solid
Molecular Weight 374.17
Formula C₈H₁₂Cl₂Pt
SMILES

Cl[Pt]Cl.C1/C=C\CC/C=C\C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Frei A, et al. Platinum Cyclooctadiene Complexes with Activity against Gram-positive Bacteria. ChemMedChem. 2021;16(20):3165-3171. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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