2. Anti-infection Cell Cycle/DNA Damage
  3. Bacterial Antibiotic DNA/RNA Synthesis
  4. Phleomycin

Phleomycin is an anticancer glycopeptide antibiotic found in Streptomyces verticillus, which cause DNA cleavage. Phleomycin binds and intercalates DNA to damage the integrity of the double helix, which is similar to Bleomycin (HY-17565A).

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Phleomycin Chemical Structure

Phleomycin Chemical Structure

CAS No. : 11006-33-0

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Based on 1 publication(s) in Google Scholar

Phleomycin Related Antibodies

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Description

Phleomycin is an anticancer glycopeptide antibiotic found in Streptomyces verticillus, which cause DNA cleavage. Phleomycin binds and intercalates DNA to damage the integrity of the double helix, which is similar to Bleomycin (HY-17565A)[1].

IC50 & Target

Glycopeptide

 

CAS No.
Appearance

Solid

Color

Light blue to blue

SMILES

[Phleomycin]
Structure Classification
Initial Source

Streptoalloteichus hindustanus
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (Need ultrasonic)

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This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
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Purity & Documentation

Purity: ≥95.0%

COA (242 KB)

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Phleomycin Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Phleomycin11006-33-0BacterialAntibioticDNA/RNA SynthesisantibioticDNA damageglycopeptideDNA-cleavingInhibitorinhibitorinhibit

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HY-126490
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