Sialylglycopeptide
Based on 1 Customer Validation
Sialylglycopeptide is an orally active glycopeptide found in egg yolk. Sialylglycopeptide inhibits the binding of Salmonella enteritidis and Escherichia coli to intestinal cells, and protects mice from Salmonella infection. Sialylglycopeptide can be used in the research of Salmonella infection.
For research use only. We do not sell to patients.
- Purity: 97.50%
- CAS No.: 189035-43-6
- Formula: C112H189N15O70
- Molecular Weight:2865.76
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Sialylglycopeptide (100-120 μM; 30 min pre-incubation with bacteria, 1 h incubation with cells) significantly inhibits the binding of Salmonella enteritidis to Caco-2 cells[1].
Sialylglycopeptide (120 μM; 30 min pre-incubation with bacteria, 1 h incubation with cells) weakly inhibits the binding of Escherichia coli K-88 to Caco-2 cells[1].
Sialylglycopeptide (0.1%; 20 h) does not induce inflammatory mediator production by J774.1/JA-4 macrophages nor inhibit zymosan-induced inflammatory mediator production in these cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:BALB/c (female, 6 weeks old, orally inoculated with Salmonella enteritidis)[1]
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Dosage:0.1% concentration in drinking water
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Administration:p.o.; continuous ad libitum; from 2 days pre-inoculation to 13 days post-inoculation
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Result:Resulted in 20% survival of mice 13 days after Salmonella enteritidis infection.
Chemical Information
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CAS No. 189035-43-6
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Appearance Solid
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Molecular Weight 2865.76
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Formula C112H189N15O70
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Color White to off-white
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : ≥ 100 mg/mL (34.89 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 0.3489 mL | 1.7447 mL | 3.4895 mL | 8.7237 mL |
| 5 mM | 0.0698 mL | 0.3489 mL | 0.6979 mL | 1.7447 mL | |
| 10 mM | 0.0349 mL | 0.1745 mL | 0.3489 mL | 0.8724 mL | |
| 15 mM | 0.0233 mL | 0.1163 mL | 0.2326 mL | 0.5816 mL | |
| 20 mM | 0.0174 mL | 0.0872 mL | 0.1745 mL | 0.4362 mL | |
| 25 mM | 0.0140 mL | 0.0698 mL | 0.1396 mL | 0.3489 mL | |
| 30 mM | 0.0116 mL | 0.0582 mL | 0.1163 mL | 0.2908 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Sialylglycopeptide Related Classifications
HY-P3302 Related Classifications
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