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hepatoprotective glycoside

" in MedChemExpress (MCE) Product Catalog:

By Targets:	AMPK (2) Apoptosis (3) Bacterial (2) Biochemical Assay Reagents (1) Drug Derivative (1) Keap1-Nrf2 (1) MMP (1) Parasite (1) Reactive Oxygen Species (ROS) (1) Reference Standards (3) Topoisomerase (1)
By Research Areas:	Cancer (5) Cardiovascular Disease (2) Infection (3) Inflammation/Immunology (5) Metabolic Disease (11) Neurological Disease (3)

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Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0664

Aucubin Maximum Cited Publications 10 Publications Verification	Bacterial	Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Aucubin is an iridoid glycoside component that acn be found in E. ulmoides. Aucubin can cross the blood-brain barrier (BBB) and has anti-anxiety, antidepressive and anti-neuroinflammatory effects. Aucubin has many biological activities, such as antioxidant, anti-aging, anti-inflammatory, antimicrobial, anti-fibrotic, anti-cancer, hepatoprotective, neuroprotective and osteoprotective effects .

HY-N2155

Tubuloside A 1 Publications Verification	Others	Metabolic Disease
Tubuloside A is a phenylethanoid glycoside with antioxidative effect and hepatoprotective activity.

HY-N5038

Mauritianin	Topoisomerase	Cardiovascular Disease Neurological Disease Metabolic Disease
Mauritianin is an orally active kaempferol glycoside. Mauritianin can be isolated from the flowers and leaves of Acalypha indica. Mauritianin is a topoisomerase I inhibitor. Mauritianin has hepatoprotective, neuroprotective, and renoprotective activities. Mauritianin increases vascular tone when used in combination with Alcesefoliside (HY-N5049) .

HY-N2447

Amarogentin 2 Publications Verification	AMPK Apoptosis	Metabolic Disease Cancer
Amarogentin is a secoiridoid glycoside that is mainly extracted from Swertia and Gentiana roots. Amarogentin exhibits many biological effects, including anti-oxidative, anti-tumour, and anti-diabetic activities. Amarogentin exerts hepatoprotective and immunomodulatory effects. Amarogentin promotes apoptosis, arrests G2/M cell cycle and downregulates of PI3K/Akt/mTOR signalling pathways. Amarogentin exerts beneficial vasculo-metabolic effect by activating AMPK .

HY-N2094

Genipin 1-β-D-gentiobioside 2 Publications Verification Genipin 1-gentiobioside; Genipin 1-β-gentiobioside; Genipin gentiobioside	Others	Inflammation/Immunology
Genipin 1-β-D-gentiobioside (Genipin 1-gentiobioside) is one of the most abundant and bioactive iridoid glycosides in Gardenia jasminoides Ellis, which possesses hepatoprotective, anti-inflammatory, antioxidant, and antithrombotic activities.

HY-125129

Carlinoside	Keap1-Nrf2	Others
Carlinoside is a flavone glycoside with hepatoprotective efficiency. Carlinoside reduces hepatic bilirubin accumulation by stimulating bilirubin-UGT activity through Nrf2 gene expression. Carlinoside has the potential to intervene hyperbilirubinemia due to liver dysfunction .

HY-N15155

Vitexin 7-O-β-D-glucopyranoside Vitexin 7-glucoside	Others	Metabolic Disease
Vitexin 7-O-β-D-glucopyranoside (Vitexin 7-glucoside) is a flavone glycoside found in Beta vulgaris var. cicla. Vitexin 7-O-β-D-glucopyranoside shows a hepatoprotective activity in primary cultured rat hepatocytes with Carbon tetrachloride (CCl4) (HY-Y0298)-induced cell toxicity .

HY-N12442

Sarmenoside III	Others	Metabolic Disease
Sarmenoside III is a flavonol glycoside with hepatoprotective activity isolated from Sedum sarmentosum.

HY-N2155R

Tubuloside A (Standard)	Reference Standards Others	Metabolic Disease
Tubuloside A (Standard) is the analytical standard of Tubuloside A. This product is intended for research and analytical applications. Tubuloside A is a phenylethanoid glycoside with antioxidative effect and hepatoprotective activity.

HY-N13159

Goodyeroside A	Others	Inflammation/Immunology
Goodyeroside A is a glycoside compound derived from the plant Goodyera that exhibits significant hepatoprotective activity. It can inhibit liver damage induced by carbon tetrachloride (HY-Y0298) in primary cultured rat hepatocytes .

HY-N15535

Cuneataside E	Others	Cancer
Cuneataside E is a phenylpropanoid glycoside compound found in Lespedeza cuneata. Cuneataside E exhibits hepatoprotective activity against the toxicity induced by N-acetyl-p-aminophenol (APAP) in the human hepatocellular carcinoma cell line HepG2. Cuneataside E is promising for research of liver diseases .

HY-N2447R

Amarogentin (Standard)	Reference Standards AMPK Apoptosis	Metabolic Disease Cancer
Amarogentin (Standard) is the analytical standard of Amarogentin. This product is intended for research and analytical applications. Amarogentin is a secoiridoid glycoside that is mainly extracted from Swertia and Gentiana roots. Amarogentin exhibits many biological effects, including anti-oxidative, anti-tumour, and anti-diabetic activities. Amarogentin exerts hepatoprotective and immunomodulatory effects. Amarogentin promotes apoptosis, arrests G2/M cell cycle and downregulates of PI3K/Akt/mTOR signalling pathways. Amarogentin exerts beneficial vasculo-metabolic effect by activating AMPK .

HY-N18256

Leonuriside B	Others	Metabolic Disease
Leonuriside B is a hepatoprotective glycoside. Leonuriside B can be found in Chinese motherwort (Leonurus japonicus Houtt). Leonuriside B can be used for the research of liver-related disorders .

HY-N17467

Forsydoitriside A	Drug Derivative	Metabolic Disease
Forsydoitriside A is an iridoid glycoside trimer found in the fruits of Forsythia suspensa. Forsydoitriside A shows no significant hepatoprotective activity against Acetaminophen (HY-66005)-induced damage in liver cells at 10 μM .

HY-N17412

Chrysandroside A	Others	Metabolic Disease
Chrysandroside A is a flavanonol glycoside found in Gordonia chrysandra Cowan. Chrysandroside A shows hepatoprotective activity .

HY-N2094R

Genipin 1-β-D-gentiobioside (Standard) Genipin 1-gentiobioside (Standard); Genipin 1-β-gentiobioside (Standard); Genipin gentiobioside (Standard)	Reference Standards Others	Inflammation/Immunology
Genipin 1-β-D-gentiobioside (Genipin 1-gentiobioside) is one of the most abundant and bioactive iridoid glycosides in Gardenia jasminoides Ellis, which possesses hepatoprotective, anti-inflammatory, antioxidant, and antithrombotic activities.

HY-N17767

Leonoside F	Others	Inflammation/Immunology
Leonoside F is a phenylethanoid glycoside compound isolated from the aerial parts of Leonurus japonicus Houtt., which protects liver cells from chemically induced damage. At a concentration of 1×10 ^-5 M, Leonoside F shows significant hepatoprotective activity against D-galactosamine-induced damage in HL-7702 liver cells, with an inhibition rate of 30.9% .

HY-182295

Negundoside	Reactive Oxygen Species (ROS) Apoptosis MMP Bacterial Parasite	Cardiovascular Disease Infection Neurological Disease
Negundoside is an iridoid glycoside compound. Negundoside exhibits hepatoprotective effects, reduces ROS, lipid peroxidation and intracellular calcium ion levels, and prevents the decrease of mitochondrial membrane potential (MMP) and apoptosis (apoptosis). Negundoside has neuroprotective effects, improves behavioral deficits, alleviates oxidative damage, and ameliorates cerebral infarction. Negundoside also possesses antibacterial and antiparasitic activities .

HY-N6998A

6-epi-Paederosidic acid	Others	Infection Cancer
6-epi-Paederosidic acid is a cyclopentanoid monoterpene glycoside found in the aerial parts of Paederia foetida L. 6-epi-Paederosidic acid does not exhibit cytotoxic activity against human tumor cells, hepatoprotective activity against APAP (HY-66005)-induced cellular toxicity, or inhibitory activity against LPS (HY-D1056)-induced nitric oxide production in murine microglia .

HY-N19759

6''-O-trans-Sinapoylgenipin gentiobioside	Biochemical Assay Reagents	Others
6''-O-trans-Sinapoylgenipin gentiobioside is an iridoid glycoside that can be found in Zhuyeqing Liquor .

Aucubin Maximum Cited Publications 10 Publications Verification	Infection Structural Classification Eucommia ulmoides Oliver Iridoids Neurological Disease Classification of Application Fields Terpenoids Eucommiaceae Plants Inflammation/Immunology Disease Research Fields Source Classification	Bacterial
Aucubin is an iridoid glycoside component that acn be found in E. ulmoides. Aucubin can cross the blood-brain barrier (BBB) and has anti-anxiety, antidepressive and anti-neuroinflammatory effects. Aucubin has many biological activities, such as antioxidant, anti-aging, anti-inflammatory, antimicrobial, anti-fibrotic, anti-cancer, hepatoprotective, neuroprotective and osteoprotective effects .

Tubuloside A 1 Publications Verification	Classification of Application Fields Simple Phenylpropanols Cistanche deserticola Ma Phenols Polyphenols Orobanchaceae Metabolic Disease Phenylpropanoids Plants Disease Research Fields Source Classification	Others
Tubuloside A is a phenylethanoid glycoside with antioxidative effect and hepatoprotective activity.

Mauritianin	Flavonols Classification of Application Fields Erythrina stricta Roxb. Plants Compositae Acalypha indica Linn. Flavonoids Phenols Polyphenols Euphorbiaceae Disease Research Fields Source Classification Cancer	Topoisomerase
Mauritianin is an orally active kaempferol glycoside. Mauritianin can be isolated from the flowers and leaves of Acalypha indica. Mauritianin is a topoisomerase I inhibitor. Mauritianin has hepatoprotective, neuroprotective, and renoprotective activities. Mauritianin increases vascular tone when used in combination with Alcesefoliside (HY-N5049) .

Amarogentin 2 Publications Verification	Gentiana scabra Bunge Iridoids Classification of Application Fields Terpenoids Gentianaceae Phenols Polyphenols Metabolic Disease Plants Disease Research Fields Source Classification	AMPK Apoptosis
Amarogentin is a secoiridoid glycoside that is mainly extracted from Swertia and Gentiana roots. Amarogentin exhibits many biological effects, including anti-oxidative, anti-tumour, and anti-diabetic activities. Amarogentin exerts hepatoprotective and immunomodulatory effects. Amarogentin promotes apoptosis, arrests G2/M cell cycle and downregulates of PI3K/Akt/mTOR signalling pathways. Amarogentin exerts beneficial vasculo-metabolic effect by activating AMPK .

Genipin 1-β-D-gentiobioside 2 Publications Verification Genipin 1-gentiobioside; Genipin 1-β-gentiobioside; Genipin gentiobioside	Iridoids Classification of Application Fields Terpenoids Rubiaceae Plants Gardenia jasminoides Ellis Inflammation/Immunology Disease Research Fields Source Classification	Others
Genipin 1-β-D-gentiobioside (Genipin 1-gentiobioside) is one of the most abundant and bioactive iridoid glycosides in Gardenia jasminoides Ellis, which possesses hepatoprotective, anti-inflammatory, antioxidant, and antithrombotic activities.

Carlinoside	Flavonoids Classification of Application Fields Flavones Cymbopogon citratus Gramineae Other Diseases Phenols Polyphenols Plants Disease Research Fields Source Classification	Keap1-Nrf2
Carlinoside is a flavone glycoside with hepatoprotective efficiency. Carlinoside reduces hepatic bilirubin accumulation by stimulating bilirubin-UGT activity through Nrf2 gene expression. Carlinoside has the potential to intervene hyperbilirubinemia due to liver dysfunction .

Vitexin 7-O-β-D-glucopyranoside Vitexin 7-glucoside	Flavonoids Flavones Amaranthaceae Plants Beta vulgaris var. cicla L. Saccharides Monosaccharides Source Classification	Others
Vitexin 7-O-β-D-glucopyranoside (Vitexin 7-glucoside) is a flavone glycoside found in Beta vulgaris var. cicla. Vitexin 7-O-β-D-glucopyranoside shows a hepatoprotective activity in primary cultured rat hepatocytes with Carbon tetrachloride (CCl4) (HY-Y0298)-induced cell toxicity .

Sarmenoside III	Phenols Polyphenols Plants Capparidaceae Cleome chelidonii L.f. Source Classification	Others
Sarmenoside III is a flavonol glycoside with hepatoprotective activity isolated from Sedum sarmentosum.

Tubuloside A (Standard)	Structural Classification Simple Phenylpropanols Cistanche deserticola Ma Phenols Polyphenols Orobanchaceae Phenylpropanoids Plants Source Classification	Reference Standards Others
Tubuloside A (Standard) is the analytical standard of Tubuloside A. This product is intended for research and analytical applications. Tubuloside A is a phenylethanoid glycoside with antioxidative effect and hepatoprotective activity.

Goodyeroside A	Crocus sativus Linn. Iridaceae Plants Saccharides Monosaccharides Source Classification	Others
Goodyeroside A is a glycoside compound derived from the plant Goodyera that exhibits significant hepatoprotective activity. It can inhibit liver damage induced by carbon tetrachloride (HY-Y0298) in primary cultured rat hepatocytes .

Cuneataside E	Piperaceae Piper crocatum Ruiz & Pav. Plants Saccharides Monosaccharides Source Classification	Others
Cuneataside E is a phenylpropanoid glycoside compound found in Lespedeza cuneata. Cuneataside E exhibits hepatoprotective activity against the toxicity induced by N-acetyl-p-aminophenol (APAP) in the human hepatocellular carcinoma cell line HepG2. Cuneataside E is promising for research of liver diseases .

Amarogentin (Standard)	Structural Classification Gentiana scabra Bunge Iridoids Terpenoids Gentianaceae Phenols Polyphenols Plants Source Classification	Reference Standards AMPK Apoptosis
Amarogentin (Standard) is the analytical standard of Amarogentin. This product is intended for research and analytical applications. Amarogentin is a secoiridoid glycoside that is mainly extracted from Swertia and Gentiana roots. Amarogentin exhibits many biological effects, including anti-oxidative, anti-tumour, and anti-diabetic activities. Amarogentin exerts hepatoprotective and immunomodulatory effects. Amarogentin promotes apoptosis, arrests G2/M cell cycle and downregulates of PI3K/Akt/mTOR signalling pathways. Amarogentin exerts beneficial vasculo-metabolic effect by activating AMPK .

Leonuriside B	Structural Classification Blepharis ciliaris (L.) B.L.Burtt Labiatae Phenols Polyphenols Plants Source Classification	Others
Leonuriside B is a hepatoprotective glycoside. Leonuriside B can be found in Chinese motherwort (Leonurus japonicus Houtt). Leonuriside B can be used for the research of liver-related disorders .

Forsydoitriside A	Structural Classification Polysaccharides Oleaceae Forsythia suspensa (Thunb.) Vahl Plants Saccharides Source Classification	Drug Derivative
Forsydoitriside A is an iridoid glycoside trimer found in the fruits of Forsythia suspensa. Forsydoitriside A shows no significant hepatoprotective activity against Acetaminophen (HY-66005)-induced damage in liver cells at 10 μM .

Chrysandroside A	Structural Classification Flavonoids Flavones Polyspora chrysandra (Cowan) Hu ex Barthol. & Ming Plants Source Classification Theaceae	Others
Chrysandroside A is a flavanonol glycoside found in Gordonia chrysandra Cowan. Chrysandroside A shows hepatoprotective activity .

Genipin 1-β-D-gentiobioside (Standard) Genipin 1-gentiobioside (Standard); Genipin 1-β-gentiobioside (Standard); Genipin gentiobioside (Standard)	Structural Classification Iridoids Terpenoids Rubiaceae Plants Gardenia jasminoides Ellis Source Classification	Reference Standards Others
Genipin 1-β-D-gentiobioside (Genipin 1-gentiobioside) is one of the most abundant and bioactive iridoid glycosides in Gardenia jasminoides Ellis, which possesses hepatoprotective, anti-inflammatory, antioxidant, and antithrombotic activities.

Leonoside F	Structural Classification Erythrophleum fordii Oliv. Monophenols Labiatae Phenols Plants Source Classification	Others
Leonoside F is a phenylethanoid glycoside compound isolated from the aerial parts of Leonurus japonicus Houtt., which protects liver cells from chemically induced damage. At a concentration of 1×10 ^-5 M, Leonoside F shows significant hepatoprotective activity against D-galactosamine-induced damage in HL-7702 liver cells, with an inhibition rate of 30.9% .

6-epi-Paederosidic acid	Structural Classification Iridoids Terpenoids Rubiaceae Plants Source Classification Paederia foetida L.	Others
6-epi-Paederosidic acid is a cyclopentanoid monoterpene glycoside found in the aerial parts of Paederia foetida L. 6-epi-Paederosidic acid does not exhibit cytotoxic activity against human tumor cells, hepatoprotective activity against APAP (HY-66005)-induced cellular toxicity, or inhibitory activity against LPS (HY-D1056)-induced nitric oxide production in murine microglia .

6''-O-trans-Sinapoylgenipin gentiobioside	Structural Classification Iridoids Terpenoids Rubiaceae Plants Gardenia jasminoides Ellis Source Classification	Biochemical Assay Reagents
6''-O-trans-Sinapoylgenipin gentiobioside is an iridoid glycoside that can be found in Zhuyeqing Liquor .

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hepatoprotective glycoside

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