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Cat. No.: HY-N6998A

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6-epi-Paederosidic acid

6-epi-Paederosidic acid is a cyclopentanoid monoterpene glycoside found in the aerial parts of Paederia foetida L. 6-epi-Paederosidic acid does not exhibit cytotoxic activity against human tumor cells, hepatoprotective activity against APAP (HY-66005)-induced cellular toxicity, or inhibitory activity against LPS (HY-D1056)-induced nitric oxide production in murine microglia.

For research use only. We do not sell to patients.

CAS No.: 435278-17-4
Formula: C₁₈H₂₄O₁₂S
Molecular Weight:464.44

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

6-epi-Paederosidic acid Chemical Structure

CAS No.: 435278-17-4

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vitro

6-epi-Paederosidic acid (Compound 8) (0.1-10.0 μg/mL; 96 h) shows no cytotoxic activity against HCT116, MCF7, BGC823, HepG2, PC9, and PANC1 human tumor cell lines, with an IC₅₀ >10 μM^[1].
6-epi-Paederosidic acid (10 μM; 24 h) exhibits no significant hepatoprotective activity against APAP (HY-66005)-induced toxicity in HepG2 cells^[1].
6-epi-Paederosidic acid (10 μM; 24 h) does not inhibit LPS (HY-D1056)-induced nitric oxide production in BV2 microglial cells, with an IC₅₀ >10 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay^[1]

Cell Line:

HCT116, MCF7, BGC823, HepG2, PC9, PANC1
Concentration:

0.1, 1.0, and 10.0 μg/mL
Incubation Time:

96 h
Result:

Showed no cytotoxic activity, with an IC₅₀ value greater than 10 μM.

Chemical Information

CAS No. 435278-17-4
Molecular Weight 464.44
Formula C₁₈H₂₄O₁₂S
SMILES

OC(C1=CO[C@H]([C@@]2([H])[C@]1([H])[C@@H](C=C2COC(SC)=O)O)O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO)=O
Structure Classification
- Terpenoids
- Iridoids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zhang WQ, et al. Cyclopentanoid monoterpene glycosides from the aerial parts of Paederia foetida L. Phytochemistry. 2026;243:114725. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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