1. Apoptosis
  2. Apoptosis
  3. Paederosidic acid

Paederosidic acid 

Cat. No.: HY-N6998
Handling Instructions

Paederosidic acid is isolated from P. scandens with anticancer and anti‐inflammation activities. Paederosidic acid inhibits lung caner cells via inducing mitochondria-mediated apoptosis.

For research use only. We do not sell to patients.

Paederosidic acid Chemical Structure

Paederosidic acid Chemical Structure

CAS No. : 18842-98-3

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Description

Paederosidic acid is isolated from P. scandens with anticancer and anti‐inflammation activities. Paederosidic acid inhibits lung caner cells via inducing mitochondria-mediated apoptosis[1].

IC50 & Target

IC50: apoptosis[1]

In Vitro

Paederosidic acid (40 μg/ml; 24 hours and 48 hours) has no significant effect on BSAS-2B cells, it exhibits obvious effects on NCI-H1650, HCC827, A549 cells with IC50 values of 40.68, 42.58, and 36.48 μg/ml, respectively[1].
Paederosidic acid induces mitochondria-mediated apoptosis via up-regulation of caspase-3, caspase-8, caspase-9, Bid, Bax, down-regulation of Bcl-2 and stimulating the release of Cyto-C from mitochondria in lung cancer cells[1].
.

Molecular Weight

464.44

Formula

C₁₈H₂₄O₁₂S

CAS No.

18842-98-3

SMILES
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Paederosidic acidApoptosisA549LungcancerPaederosidicacidInhibitorinhibitorinhibit

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