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Results for "

lysine+residue

" in MedChemExpress (MCE) Product Catalog:

71

Inhibitors & Agonists

1

Screening Libraries

2

Fluorescent Dyes

12

Biochemical Assay Reagents

7

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9

Natural
Products

6

Isotope-Labeled Compounds

5

Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B2227
    Lactic acid
    50+ Cited Publications

    DL-Lactic acid; E-270

    		 Environmental Pollutants Endogenous Metabolite Bacterial Hydroxycarboxylic Acid Receptor (HCAR) Infection Metabolic Disease Inflammation/Immunology Cancer
    Lactic acid (DL-Lactic acid) is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Lactic acid is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Lactic acid is an oncometabolite and has immune protective role of lactate in anti-tumor immunity . Lactic acid also has antimicrobial activity, which can be used as a food preservative .
    Lactic acid
  • HY-B2227B
    Lactic acid sodium (60% w/w in water)
    50+ Cited Publications

    DL-Lactic acid sodium; E-270 sodium

    		 Environmental Pollutants Endogenous Metabolite Bacterial Hydroxycarboxylic Acid Receptor (HCAR) Infection Metabolic Disease Inflammation/Immunology Cancer
    Lactic acid (DL-Lactic acid) sodium (60% w/w in water) is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Lactic acid sodium (60% w/w in water) is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Lactic acid sodium (60% w/w in water) is an oncometabolite and has immune protective role of lactate in anti-tumor immunity . Lactic acid sodium (60% w/w in water) also has antimicrobial activity, which can be used as a food preservative .
    This product has a content (w/w) of 60%, and 1 mL of the system contains 798 mg of Lactic acid sodium, i.e., a concentration of 798 mg/mL (i.e., 7.12 M).
    Lactic acid sodium (60% w/w in water)
  • HY-B0236
    6-Aminocaproic acid
    4 Publications Verification

    EACA; Epsilon-Amino-n-caproic Acid; 6-Aminohexanoic acid

    		 PAI-1 Plasminogen/Plasmin PROTAC Linkers Metabolic Disease Cancer
    6-Aminocaproic acid (EACA), a monoamino carboxylic acid, is a potent and orally active inhibitor of plasmin and plasminogen. 6-Aminocaproic acid is a potent antifibrinolytic agent. 6-Aminocaproic acid prevents clot lysis through the competitive binding of lysine residues on plasminogen, inhibiting plasmin formation and reducing fibrinolysis. 6-Aminocaproic acid can be used for the research of bleeding disorders .
    6-Aminocaproic acid
  • HY-P3208
    Endoproteinase Lys-C
    2 Publications Verification

    		 Biochemical Assay Reagents Others
    Endoproteinase Lys-C is a protease that cleaves proteins on the C-terminal side of lysine residues and is commonly used for protein sequencing .
    Endoproteinase Lys-C
  • HY-151835
    DBCO-PEG24-NHS ester

    		ADC Linker Others
    DBCO-PEG24-NHS ester is a click chemistry reagent. DBCO-PEG24-NHS ester is a click chemistry PEG reagent containing NHS ester that is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and provides a long and flexible connection that minimizes steric hindrance involved with ligation. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research use only .
    DBCO-PEG24-NHS ester
  • HY-W035129
    endo-BCN-NHS carbonate

    		Biochemical Assay Reagents Others
    endo-BCN-NHS carbonate is an elastin-like protein (ELP) modification reagent. endo-BCN-NHS carbonate can react with lysine residues in ELP to make ELP carry BCN groups, and then cross-link ELP through strain-promoted azide-alkyne cycloaddition (SPAAC) reaction. endo-BCN-NHS carbonate promotes hydrogel formation. endo-BCN-NHS carbonate is mainly used in cell encapsulation related research .
    endo-BCN-NHS carbonate
  • HY-10587
    BIX-01294
    25+ Cited Publications

    		 Histone Methyltransferase Autophagy Cancer
    BIX-01294 is a reversible and highly selective G9a and GLP Histone Methyltransferase inhibitor, with IC50s of of 1.7 μM and 0.9 μM, respectively. BIX-01294 inhibits G9a/GLP by competing for binding with the amino acids N-terminal of the substrate lysine residue. BIX-01294, a (1H-1,4-diazepin-1-yl)-quinazolin-4-yl amine derivative, induces necroptosis and autophagy. BIX-01294 has antitumor activity in recurrent tumor cells .
    BIX-01294
  • HY-159607
    PRT3789

    		PROTACs SWI/SNF Complex Cancer
    PRT3789 is a selective SMARCA2 PROTAC degrader (DC50 in HeLa cell: 0.72 nM for SMARCA2, 14 nM for SMARCA4). PRT3789 forms a stable ternary complex with Von Hippel-Lindau (VHL) E3 ligase, induces polyubiquitination at SMARCA2-specific lysine residues, and drives proteasome-dependent SMARCA2 degradation. PRT3789 disrupts SWI/SNF chromatin remodeling complex integrity, induces dissociation of specific subunits, suppresses oncogenic gene expression, reduces chromatin accessibility, and upregulates antigen processing/presentation-related gene expression. PRT3789 induces synthetic lethality, inhibits proliferation and colony formation, and drives tumor growth inhibition and regression in SMARCA4-deficient contexts. PRT3789 can be used for the research of SMARCA4-mutated solid tumors, non-small cell lung cancer, endometrial cancer, colorectal cancer, bladder cancer, esophageal cancer, ovarian cancer, and gastric cancer .
    PRT3789
  • HY-P3208A
    Endoproteinase Lys-C (Tag-free)
    1 Publications Verification

    		 Biochemical Assay Reagents Others
    Endoproteinase Lys-C (Tag-free) is a protease that cleaves proteins on the C-terminal side of lysine residues and is commonly used for protein sequencing .
    Endoproteinase Lys-C (Tag-free)
  • HY-157414
    Azide-A-DSBSO crosslinker

    		Biochemical Assay Reagents Others
    Azide-A-DSBSO crosslinker is a mass spectrometry (MS) cleavable, membrane permeable, homobifunctional, azide-labeled, acid-cleavable crosslinking peptide. Azide-A-DSBSO crosslinker crosslinks proteins via NHS ester reaction with lysine residues. Azide-A-DSBSO crosslinker can be used to study protein-protein interactions by cross-linking mass spectrometry (XL-MS) [1] .
    Azide-A-DSBSO crosslinker
  • HY-B2227C
    Lactic acid potassium
    50+ Cited Publications

    DL-Lactic acid potassium; E-270 potassium

    		 Endogenous Metabolite Hydroxycarboxylic Acid Receptor (HCAR) Bacterial Infection Metabolic Disease Inflammation/Immunology Cancer
    Lactic acid (DL-Lactic acid) potassium is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Lactic acid potassium is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Lactic acid potassium is an oncometabolite and has immune protective role of lactate in anti-tumor immunity . Lactic acid also potassium has antimicrobial activity, which can be used as a food preservative .
    Lactic acid potassium
  • HY-151827
    DBCO-PEG2-NHS ester

    		ADC Linker Others
    DBCO-PEG2-NHS ester is a click chemistry reagent containing an azide group. DBCO-PEG2-NHS ester is a click chemistry PEG reagent containing NHS ester that is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and provides a long and flexible connection that minimizes steric hindrance involved with ligation. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research use only .
    DBCO-PEG2-NHS ester
  • HY-P3208B
    Endoproteinase Lys-C (MS grade)

    		Biochemical Assay Reagents Others
    Endoproteinase Lys-C (MS grade) is a hydrolase that cleaves peptide bonds at the carboxyl side of lysine residues. Endoproteinase Lys-C (MS grade) causes non-specific hydrolysis of peptide bonds linked to the carboxyl groups of non-lysine residues, resulting in partial cleavage at these sites .
    Endoproteinase Lys-C (MS grade)
  • HY-B2227A
    Lactic acid calcium
    50+ Cited Publications

    DL-Lactic acid calcium; E-270 calcium

    		 Environmental Pollutants Endogenous Metabolite Bacterial Hydroxycarboxylic Acid Receptor (HCAR) Infection Neurological Disease Inflammation/Immunology Cancer
    Lactic acid (DL-Lactic acid) calcium is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Lactic acid calcium is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Lactic acid calcium is an oncometabolite and has immune protective role of lactate in anti-tumor immunity . Lactic acid calcium also has antimicrobial activity, which can be used as a food preservative .
    Lactic acid calcium
  • HY-B2227R
    Lactic acid (Standard)

    DL-Lactic acid (Standard); E-270 (Standard)

    		 Reference Standards Endogenous Metabolite Hydroxycarboxylic Acid Receptor (HCAR) Bacterial Infection Metabolic Disease Inflammation/Immunology Cancer
    Lactic acid (Standard) (DL-Lactic acid (Standard)) is the analytical standard of Lactic acid (HY-B2227). This product is intended for research and analytical applications. Lactic acid (DL-Lactic acid) is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Lactic acid is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Lactic acid is an oncometabolite and has immune protective role of lactate in anti-tumor immunity . Lactic acid also has antimicrobial activity, which can be used as a food preservative .
    Lactic acid (Standard)
  • HY-W089800
    trans-2-Nonenal

    trans-2-Nonen-1-al

    		 COX Lipoxygenase Apoptosis Cardiovascular Disease Inflammation/Immunology
    trans-2-Nonenal (trans-2-Nonen-1-al) is an endogenous peroxidation product of polyunsaturated fatty acids, acting as an inhibitor of COX and 12-LOX, as well as an inducer of apoptosis. trans-2-Nonenal is also a malodorous compound secreted by the human body, and its content gradually increases with aging. trans-2-Nonenal inhibits the activities of multiple enzymes such as platelet membrane-bound PTPase, preferentially covalently modifies proteins at lysine residues to form immunogenic adducts, and regulates platelet Arachidonic acid (HY-109590) metabolism. trans-2-Nonenal also exhibits significant cytotoxicity, reduces the viability of keratinocytes, promotes their apoptosis, and effectively decreases the thickness of epidermal models and the number of proliferating cells. trans-2-Nonenal is commonly used in studies of thrombotic, atherosclerotic diseases, renal adenocarcinoma, etc. .
    trans-2-Nonenal
  • HY-W437745
    Desthiobiotin-NHS ester

    		Fluorescent Dye Others
    Desthiobiotin-NHS ester is a biotinylated biochemical assay reagent that reacts with amine groups (such as lysine residues) of proteins or other biomolecules to form stable amide bonds. Desthiobiotin-NHS ester can be used as probes for metalloproteins .
    Desthiobiotin-NHS ester
  • HY-108239
    BIX-01294 trihydrochloride
    25+ Cited Publications

    		 Histone Methyltransferase Autophagy Cancer
    BIX-01294 trihydrochloride is a reversible and highly selective G9a and GLP Histone Methyltransferase inhibitor, with IC50s of of 1.7 μM and 0.9 μM, respectively. BIX-01294 trihydrochloride inhibits G9a/GLP by competing for binding with the amino acids N-terminal of the substrate lysine residue. BIX-01294 trihydrochloride, a (1H-1,4-diazepin-1-yl)-quinazolin-4-yl amine derivative, induces necroptosis and autophagy. BIX-01294 trihydrochloride has antitumor activity in recurrent tumor cells .
    BIX-01294 trihydrochloride
  • HY-126487A
    H-Arg-Lys-OH TFA

    		Endogenous Metabolite Metabolic Disease
    H-Arg-Lys-OH TFA is a dipeptide formed from L-arginyl and L-lysine residues .
    H-Arg-Lys-OH TFA
  • HY-W043748
    2,5-Dioxopyrrolidin-1-yl acrylate

    N-Succinimidyl acrylate

    		 Biochemical Assay Reagents Others
    2,5-Dioxopyrrolidin-1-yl acrylate (N-Succinimidyl acrylate) is a protein crosslinker. 2,5-Dioxopyrrolidin-1-yl acrylate can react with a monoclonal anti-horseradish peroxidase IgG antibody (anti-HRP) to modify lysine residues .
    2,5-Dioxopyrrolidin-1-yl acrylate
  • HY-160773
    DBCO-PEG6-NHS ester

    		Biochemical Assay Reagents Others
    DBCO-PEG6-NHS ester is a click chemistry PEG reagent containing an NHS ester that reacts specifically with primary amines, such as side chains of lysine residues or aminosilane-coated surfaces, under neutral or slightly alkaline conditions. , efficient reaction to form covalent bonds. DBCO-PEG6-NHS ester also contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
    DBCO-PEG6-NHS ester
  • HY-78035
    Citraconic anhydride

    Methylmaleic anhydride

    		 Biochemical Assay Reagents Others
    Citraconic anhydride (Methylmaleic anhydride) is a derivative of maleic anhydride (HY-Z0060) and novel antigen retrieval solution. Citraconic anhydride reversibly blocks protein amino groups, stabilizing specific enzymes and improving their catalytic performance. Citraconic anhydride reacts with free amino groups on proteins (especially lysine residues), converting positively charged NH3 + into carboxyl groups, thereby disrupting methylene bridge crosslinks caused by Formaldehyde during antigen retrieval. Citraconic anhydride functionalizes Isotactic polypropylene. Citraconic anhydride precisely responds to pH changes to achieve reversible modification. Citraconic anhydride is irritating to skin and eyes .
    Citraconic anhydride
  • HY-B2227BS
    Lactic acid-d4 sodium (60% w/w in water)

    DL-Lactic acid-d4 sodium; E-270-d4 sodium

    		 Isotope-Labeled Compounds Endogenous Metabolite Hydroxycarboxylic Acid Receptor (HCAR) Bacterial Infection Metabolic Disease Inflammation/Immunology Cancer
    Lactic acid-d4 (DL-Lactic acid-d4) sodium (60% in water) is the deuterium labeled Lactic acid sodium (60% in water) (HY-B2227B) . Lactic acid (DL-Lactic acid) sodium (60% w/w in water) is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Lactic acid sodium (60% w/w in water) is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Lactic acid sodium (60% w/w in water) is an oncometabolite and has immune protective role of lactate in anti-tumor immunity . Lactic acid sodium (60% w/w in water) also has antimicrobial activity, which can be used as a food preservative .
    Lactic acid-d4 sodium (60% w/w in water)
  • HY-B2227BS1
    Lactic acid-d3 sodium (60% w/w in water)

    DL-Lactic acid-d3 sodium; E-270-d3 sodium

    		 Isotope-Labeled Compounds Endogenous Metabolite Hydroxycarboxylic Acid Receptor (HCAR) Bacterial Infection Metabolic Disease Inflammation/Immunology Cancer
    Lactic acid-d3 (DL-Lactic acid-d3) sodium (60% in water) is the deuterium labeled Lactic acid sodium (60% in water) (HY-B2227B) . Lactic acid (DL-Lactic acid) sodium (60% w/w in water) is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Lactic acid sodium (60% w/w in water) is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Lactic acid sodium (60% w/w in water) is an oncometabolite and has immune protective role of lactate in anti-tumor immunity . Lactic acid sodium (60% w/w in water) also has antimicrobial activity, which can be used as a food preservative .
    Lactic acid-d3 sodium (60% w/w in water)
  • HY-145365
    DGN549-L

    		Drug-Linker Conjugates for ADC Cancer
    DGN549-L is a DNA alkylator and can be utilized for antibody conjugation at lysine residues. DGN549-L can be used in the synthesis of antibody-drug conjugates (ADCs) .
    DGN549-L
  • HY-139201E
    Poly-D-lysine hydrobromide (MW 150000-300000)

    PDLHB (MW 150000-300000)

    		 CaSR 5-HT Receptor Metabolic Disease
    Poly-D-lysine hydrobromide (MW 150000-300000) is a synthetic polymer composed of D-lysine residues and is one of the most widely used matrices in neural cell culture applications. Poly-D-lysine hydrobromide (MW 150000-300000) can be used as a non-specific cell adhesion enhancer. Poly-D-lysine hydrobromide (MW 30000-70000) is an orally active CaSR agonist peptide that indirectly activates the 5-HT₃ receptor signaling pathway, delaying gastric emptying and thereby slowing the rate at which glucose enters the small intestine and is absorbed .
    Poly-D-lysine hydrobromide (MW 150000-300000)
  • HY-B0236A
    6-Aminocaproic acid hydrochloride

    EACA hydrochloride; Epsilon-Amino-n-caproic Acid hydrochloride; 6-Aminohexanoic acid hydrochloride

    		 Drug Derivative PAI-1 Metabolic Disease Cancer
    6-Aminocaproic acid hydrochloride, a monoamino carboxylic acid, is a potent and orally active inhibitor of plasmin and plasminogen. 6-Aminocaproic acid is a potent antifibrinolytic agent. 6-Aminocaproic acid prevents clot lysis through the competitive binding of lysine residues on plasminogen, inhibiting plasmin formation and reducing fibrinolysis. 6-Aminocaproic acid can be used for the research of bleeding disorders .
    6-Aminocaproic acid hydrochloride
  • HY-B2227D
    Calcium 2-hydroxypropanoate pentahydrate
    10+ Cited Publications

    		 Environmental Pollutants Endogenous Metabolite Metabolic Disease Inflammation/Immunology Cancer
    Calcium 2-hydroxypropanoate (pentahydrate) is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Calcium 2-hydroxypropanoate (pentahydrate) is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Calcium 2-hydroxypropanoate (pentahydrate) is an oncometabolite and has immune protective role of lactate in anti-tumor immunity .
    Calcium 2-hydroxypropanoate pentahydrate
  • HY-B0236S
    6-Aminocaproic acid-d6

    EACA-d6; Epsilon-Amino-n-caproic acid-d6; 6-Aminohexanoic acid-d6

    		 Isotope-Labeled Compounds Metabolic Disease
    6-Aminocaproic acid-d6 is deuterium labeled 6-Aminocaproic acid. 6-Aminocaproic acid (EACA), a monoamino carboxylic acid, is a potent and orally active inhibitor of plasmin and plasminogen. 6-Aminocaproic acid is a potent antifibrinolytic agent. 6-Aminocaproic acid prevents clot lysis through the competitive binding of lysine residues on plasminogen, inhibiting plasmin formation and reducing fibrinolysis. 6-Aminocaproic acid can be used for the research of bleeding disorders .
    6-Aminocaproic acid-d6
  • HY-P10463
    ssK36

    		Histone Methyltransferase Cancer
    ssK36 is a supersubstrate peptide of the histone methyltransferase (SET) domain protein 2 (SETD2), and ssK36 is designed for the SETD2 protein, a specific PKMT. ssK36 is responsible in human cells for adding methyl groups to the 36th lysine residue of histone H3 (H3K36) to form H3K36me3. ssK36 can be methylated by SETD2 at a rate more than 100 times faster than the natural substrate H3K36. ssK36 can be used to study the catalytic mechanism of PKMTs, especially substrate specificity and catalytic efficiency .
    ssK36
  • HY-113025A
    L-hydroxylysine dihydrochloride

    (2S,5R)-5-Hydroxylysine dihydrochloride

    		 Endogenous Metabolite Others
    L-hydroxylysine dihydrochloride ((2S,5R)-5-Hydroxylysine dihydrochloride), an amino acid, is exclusive to collagen protein, which is formed by posttranslational hydroxylation of some lysine residues .
    L-hydroxylysine dihydrochloride
  • HY-W848699
    FAM NHS ester, 6-isomer

    		Fluorescent Dye Others
    FAM NHS ester, 6-isomer is a hydrophilic fluorophore. The NHS ester can react specifically and efficiently with primary amines such as the side chain of lysine residue or aminosilane-coated surfaces at neutral or slight basic conditions to form a covalent bond.
    FAM NHS ester, 6-isomer
  • HY-W011118
    DTPA anhydride

    		Radionuclide-Drug Conjugates (RDCs) Cancer
    DTPA anhydride is a bifunctional chelator whose anhydride can react with amino groups in proteins (such as lysine residues) to form stable amide bonds. DTPA anhydride can also bind to radionuclides to synthesize radionuclide-labeled drug conjugates (RDCs). RDCs have the ability to specifically target biomolecules and can be used in medical imaging or therapy.
    DTPA anhydride
  • HY-E70453
    Human prostate transglutaminase

    Prostate Transglutaminase; TG4; TGase 4

    		 Biochemical Assay Reagents Metabolic Disease
    Human prostate transglutaminase (TG4; TGase 4) is an enzyme that mediates the transfer of acyl groups from glutamine residues in proteins or peptides to primary amines and belongs to the prostate transglutaminase protein family. Human prostate transglutaminase forms an ε-(γ-glutamyl)lysine bond between proteins by transferring the acyl group of a peptide-bound glutamine residue to the primary amino group of a peptide-bound lysine residue .
    Human prostate transglutaminase
  • HY-136952
    p-SCN-Bn-HOPO

    		Biochemical Assay Reagents Radionuclide-Drug Conjugates (RDCs) Cancer
    p-SCN-Bn-HOPO is a bifunctional chelator that forms stable octadentate complexes with Zr (IV) and 89Zr 4+ via four 1,2-hydroxypyridone groups. p-SCN-Bn-HOPO conjugates with antibodies through the formation of thiourea bonds with lysine residues, and enables efficient 89Zr radiolabeling under mild conditions. p-SCN-Bn-HOPO inhibits bone uptake of free radiometals, stabilizes radiometal-antibody conjugates, and achieves PET imaging with low background and enhanced tumor-to-organ contrast. p-SCN-Bn-HOPO can be used in breast cancer-related research .
    p-SCN-Bn-HOPO
  • HY-P10463A
    ssK36 TFA

    		Histone Methyltransferase Cancer
    ssK36 TFA is a supersubstrate peptide of the histone methyltransferase (SET) domain protein 2 (SETD2) , and ssK36 TFA is designed for the SETD2 protein, a specific PKMT. ssK36 TFA is responsible in human cells for adding methyl groups to the 36th lysine residue of histone H3 (H3K36) to form H3K36me3. ssK36 TFA can be methylated by SETD2 at a rate more than 100 times faster than the natural substrate H3K36. ssK36 TFA can be used to study the catalytic mechanism of PKMTs, especially substrate specificity and catalytic efficiency .
    ssK36 TFA
  • HY-126487
    H-Arg-Lys-OH

    		Endogenous Metabolite Metabolic Disease
    H-Arg-Lys-OH is a dipeptide formed from L-arginyl and L-lysine residues .
    H-Arg-Lys-OH
  • HY-W009033
    Cbz-Lys(Boc)-OH

    		Biochemical Assay Reagents Amino Acid Derivatives Others
    Cbz-Lys(Boc)-OH is a protected amino acid, primarily utilized in peptide synthesis, protein engineering, and drug development, particularly in research involving lysine residues .
    Cbz-Lys(Boc)-OH
  • HY-W591479
    MC-Val-Ala-NHS ester

    		ADC Linker Cancer
    MC-Val-Ala-NHS ester is a cleavable ADC linker with a malimide group and an NHS ester group. The Val-Ala linkers can be cleaved by Cathepsin B. Maleimide group is reactive toward thiol groups. MC is reactive with thiol moieties. The NHS ester is able to react specifically and efficiently with amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond.
    MC-Val-Ala-NHS ester
  • HY-118112
    4-N-Maleimidobenzoicacid-NHS

    		Biochemical Assay Reagents Others
    4-N-Maleimidobenzoicacid-NHS is a PEG linker that finds utility in bioconjugation endeavors and protein labeling ventures. Specifically designed for selective reaction with thiol groups, the maleimide group establishes covalent linkages, thereby facilitating the coupling of proteins, peptides, or diverse molecules to thiol-bearing biomolecules. The NHS ester is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic conditions to form a covalent bond.
    4-N-Maleimidobenzoicacid-NHS
  • HY-164144
    EPZ033294

    		Histone Methyltransferase Cancer
    EPZ033294 is an inhibitor of SYMD2 (IC50 is 3.9 nM). SYMD2 itself has catalytic activity and can methylate the lysine residue of BTF3 to BTF3me1, which was experimentally demonstrated by detecting an IC50 of 2.9 nM for inhibition of BTF3ME1 by SYMD2, indicating an active inhibition of SYMD2 by EPZ033294. EPZ033294 (0-50 µM) has an inhibitory effect on SYMD2 and a concentration-dependent inhibitory effect in 293T .
    EPZ033294
  • HY-137251
    Sulfo-MBS sodium

    		Biochemical Assay Reagents Others
    Sulfo-MBS sodium is a heterobifunctional crosslinker with a maleimide group and an N-hydroxysuccinimide (NHS) ester group, which can react with cysteine residues and lysine residues on proteins. Sulfo-MBS sodium be used for protein cross-linking studies .
    Sulfo-MBS sodium
  • HY-174365H
    mPEG-NPC (MW:20000)

    		Biochemical Assay Reagents Others
    mPEG-NPC (MW 20000) is an important PEG derivative whose reactive groups can be used to modify proteins, peptides or any other compounds with available amino groups at lysine residues or N-terminus .
    mPEG-NPC (MW:20000)
  • HY-174365D
    mPEG10000-NPC

    		Biochemical Assay Reagents Others
    mPEG10000-NPC is an important PEG derivative whose reactive groups can be used to modify proteins, peptides or any other compounds with available amino groups at lysine residues or N-terminus .
    mPEG10000-NPC
  • HY-174365E
    mPEG40000-NPC

    		Biochemical Assay Reagents Others
    mPEG40000-NPC is an important PEG derivative whose reactive groups can be used to modify proteins, peptides or any other compounds with available amino groups at lysine residues or N-terminus .
    mPEG40000-NPC
  • HY-174365
    mPEG1000-NPC

    		Biochemical Assay Reagents Others
    mPEG1000-NPC is an important PEG derivative whose reactive groups can be used to modify proteins, peptides or any other compounds with available amino groups at lysine residues or N-terminus .
    mPEG1000-NPC
  • HY-155442
    MIQ-N-succinate

    		Biochemical Assay Reagents Inflammation/Immunology
    MIQ-N-succinate is a hapten with a four-carbon chain. MIQ-N-succinate consist of MIQ and succinic anhydride. MIQ-N-succinate has a carboxylic acid end group to attach to the lysine residues on the carrier proteins .
    MIQ-N-succinate
  • HY-43781
    Fmoc-Lys(Boc)-PAB-OH

    		Biochemical Assay Reagents Others
    Fmoc-Lys(Boc)-PAB-OH is a peptide linker containing an Fmoc-protected amine and a Boc-protected lysine residue. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations.
    Fmoc-Lys(Boc)-PAB-OH
  • HY-122039
    Hypusine dihydrochloride

    		Amino Acid Derivatives Others
    Hypusine dihydrochloride is a natural amino acid found only in the eukaryotic translation initiation factor 5A (eIF-5A). Hypusine is formed by the transfer of the butylamine portion from spermidine to the ϵ-amino group of a specific lysine residue of eIF-5A precursor and by the hydroxylation at carbon 2 of the incoming 4-aminobutyl moiety .
    Hypusine dihydrochloride
  • HY-W739603
    Cy5-bifunctional dye potassium

    		Fluorescent Dye Others
    Cy5-bifunctional dye potassium is a water soluble bifunctional dye possessing two terminal NHS ester functions. The NHS esters can react specifically and efficiently with primary amines such as the side chain of lysine residue or aminosilane-coated surfaces at neutral or slight basic conditions to form a covalent bond. The dye is useful for the cross-conjugation of amines, and for other advanced labeling applications.
    Cy5-bifunctional dye potassium

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