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  3. 6-Aminocaproic acid hydrochloride

6-Aminocaproic acid hydrochloride (Synonyms: EACA hydrochloride; Epsilon-Amino-n-caproic Acid hydrochloride; 6-Aminohexanoic acid hydrochloride)

Cat. No.: HY-B0236A
Handling Instructions

6-Aminocaproic acid hydrochloride, a monoamino carboxylic acid, is a potent and orally active inhibitor of plasmin and plasminogen. 6-Aminocaproic acid is a potent antifibrinolytic agent. 6-Aminocaproic acid prevents clot lysis through the competitive binding of lysine residues on plasminogen, inhibiting plasmin formation and reducing fibrinolysis. 6-Aminocaproic acid can be used for the research of bleeding disorders.

For research use only. We do not sell to patients.

6-Aminocaproic acid hydrochloride Chemical Structure

6-Aminocaproic acid hydrochloride Chemical Structure

CAS No. : 4321-58-8

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Description

6-Aminocaproic acid hydrochloride, a monoamino carboxylic acid, is a potent and orally active inhibitor of plasmin and plasminogen. 6-Aminocaproic acid is a potent antifibrinolytic agent. 6-Aminocaproic acid prevents clot lysis through the competitive binding of lysine residues on plasminogen, inhibiting plasmin formation and reducing fibrinolysis. 6-Aminocaproic acid can be used for the research of bleeding disorders[1][2].

In Vitro

6-Aminocaproic acid hydrochloride (20-180 μg/mL) inhibits fibrinolysis in plasma of Asian elephants, with an effective concentration of 61.5 μg/mL[2].
6-Aminocaproic acid hydrochloride can be used as a hydrophobic linker to improve near-infrared fluorescence imaging and photothermal cancer therapy of PEGylated indocyanine green[4].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

6-Aminocaproic acid hydrochloride (20-100 mg/kg; a single p.o.) inhibits fibrinolysis at all doses tested in dogs[3].
6-Aminocaproic acid hydrochloride (20-100 mg/kg; a single p.o.) is rapidly absorbed (Tmax=1 h) and eliminated rapidly in dogs[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

167.63

Formula

C6H14ClNO2

CAS No.
SMILES

O=C(O)CCCCCN.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Product Name:
6-Aminocaproic acid hydrochloride
Cat. No.:
HY-B0236A
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