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Results for "

peptide chemistry

" in MedChemExpress (MCE) Product Catalog:

49

Inhibitors & Agonists

7

Fluorescent Dyes

4

Biochemical Assay Reagents

3

Peptides

33

Click Chemistry

3

Oligonucleotides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-145934
    UDP-GalNAz disodium
    1 Publications Verification

    UDP-N-azidoacetylgalactosamine disodium

    		 Biochemical Assay Reagents OGT Glycosidase Metabolic Disease
    UDP-GalNAz (UDP-N-azidoacetylgalactosamine) disodium is the analogue of UDP-GalNAc disodium (HY-114365). UDP-GalNAc disodium is the donor substrate of many N-acetylgalactosaminyltransferases, enzymes which transfer GalNAc from the nucleotide sugar to a saccharide or peptide acceptor. UDP-GalNAz disodium is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .
    UDP-GalNAz disodium
  • HY-140739
    DSPE-PEG2000-Maleimide sodium (purity>95%)
    2 Publications Verification

    		 Liposome Neurological Disease Cancer
    DSPE-PEG2000-Maleimide sodium (purity>95%) is a phospholipid-PEG conjugate. DSPE-PEG2000-Maleimide utilizes the amphiphilicity of DSPE to insert into the lipid bilayer of liposomes or nanoparticles. DSPE-PEG2000-Maleimide covalently couples to the sulfhydryl (-SH) of ligands (such as antibodies, peptides, or proteins) via thiol-maleimide click chemistry, giving the particles targeting capabilities. DSPE-PEG2000-Maleimide sodium (purity>95%) can be used in the researches of breast cancer, lymphoma, and inherited retinal degeneration .
    DSPE-PEG2000-Maleimide sodium (purity>95%)
  • HY-Y1666
    2,2′-Dipyridyl disulfide

    		Biochemical Assay Reagents Others
    2,2′-Dipyridyl disulfide is a useful reagent for the determination of sulfhydryl groups. 2,2′-Dipyridyl disulfide is a common reagent in peptide chemistry, often used in oxidation–reduction condensations to form peptide bonds or in coupling reactions to form disulfide-linked heterodimers .
    2,2′-Dipyridyl disulfide
  • HY-151696
    TCO-PEG3-maleimide

    		ADC Linker Others
    TCO-PEG3-maleimide (TCO-PEG3-NEM) is a click chemistry reagent. TCO-PEG3-maleimide efficiently binds TCO (trans-cyclooctene) moiety to thiol-containing molecules (such as antibodies, cysteine-containing peptides) .
    TCO-PEG3-maleimide
  • HY-145934A
    UDP-GlcNAz disodium

    		OGT Biochemical Assay Reagents Glycosidase Metabolic Disease
    UDP-GlcNAz disodium is the analogue of UDP-GlcNAc disodium (HY-112174). UDP-GlcNAc disodium is the donor substrate of many N-acetylgalactosaminyltransferases, enzymes which transfer GlcNAc from the nucleotide sugar to a saccharide or peptide acceptor. UDP-GlcNAc disodium is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .
    UDP-GlcNAz disodium
  • HY-155788
    DSPE-PEG-DBCO ammonium

    		Biochemical Assay Reagents Others
    DSPE-PEG-DBCO ammonium is the ammonium salt form of DSPE-PEG-DBCO. DSPE-PEG-DBCO ammonium is utilized in copper-free click chemistry through SPAAC conjugation with an azido-functionalized peptide ligand. DSPE-PEG-DBCO ammonium is applied in drug-delivery and nanoparticle research .
    DSPE-PEG-DBCO ammonium
  • HY-W011412
    TSTU

    		Biochemical Assay Reagents Others
    TSTU is used as a coupling reagent in peptide chemistry. TSTU can convert carboxylic acids into the corresponding N-hydroxysuccinimidyl (NHS) esters. TSTU can be applied to the attachment of labels to peptides, proteins, etc .
    TSTU
  • HY-D0820
    CY5-YNE

    Sulfo-Cyanine5-alkyne

    		 Fluorescent Dye Others
    CY5-YNE (Sulfo-Cyanine5-alkyne) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides (Ex: 650 nM; Em: 680 nm). CY5-YNE is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    CY5-YNE
  • HY-151726
    Azido-PEG(4)-Val-Cit-PAB-PNP

    		ADC Linker Others
    Azido-PEG(4)-Val-Cit-PAB-PNP is a cleavable peptide ADC linker. Azido-PEG(4)-Val-Cit-PAB-PNP is a click chemistry reagent containing an azide group. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    Azido-PEG(4)-Val-Cit-PAB-PNP
  • HY-151711
    Sulfo-Cy5.5 Azide

    		Fluorescent Dye Others
    Sulfo-Cy5.5 Azide is a click chemistry reagent containing an azide group. Sulfo-Cy5.5 Azide is also a water-soluble dye (Ex=673 nm, Em=707 nm), which designed to label sensitive molecules such as peptides, proteins and oligonucleotides. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    Sulfo-Cy5.5 Azide
  • HY-D0818
    CY3-YNE

    Sulfo-Cyanine3-alkyne

    		 Fluorescent Dye Others
    CY3-YNE (Sulfo-Cyanine3-alkyne) is a dye for the labeling of soluble proteins, peptides, and oligonucleotides/DNA. CY3-YNE is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    CY3-YNE
  • HY-151859
    N3-Gly-Gly-OH

    		Biochemical Assay Reagents Others
    N3-Gly-Gly-Gly-OH is a click chemistry reagent containing an azide group. N3-Gly-Gly-OH undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing an alkyne group. N3-Gly-Gly-OH also undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. N3-Gly-Gly-Gly-OH can be used to construct peptide-like ADC linkers via click chemistry .
    N3-Gly-Gly-OH
  • HY-151783
    DAPOA

    		ADC Linker Others
    DAPOA is a click chemistry reagent containing an azide group. DAPOA can be used in peptide synthesis as a linker that can be further modified at the azido-groups using Staudinger ligation or click-chemistry . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    DAPOA
  • HY-D1052
    Cy7-YNE

    		Fluorescent Dye Cancer
    Cy7-YNE is a fluorescence labeling agent (Ex=700-770 nm，Em=790 nm). Cyanine dyes are used to label proteins, antibodies, and peptides. Cy7-YNE is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Cy7-YNE
  • HY-151829
    Fmoc-L-Asn(EDA-N3)-OH

    		ADC Linker Others
    Fmoc-L-Asn(EDA-N3)-OH is a click chemistry reagent containing an azide group. This building block is reported in literature for the modification of Amanitin via Click Chemistry. Alpha-Amanitin is the deadliest member of the amatoxin peptide family produced by the death-cap mushroom A. phalloides. It is an orally available, rigid, bicyclic octapeptide and one of the most lethal known natural products (LD50 = 50-100 μg/kg) acting as highly selective allosteric inhibitor of the RNA polymerase II . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    Fmoc-L-Asn(EDA-N3)-OH
  • HY-D2891
    5-TAMRA-DBCO

    		Fluorescent Dye Others
    5-TAMRA-DBCO is a fluorescent dye that combines 5-TAMRA (HY-15942) with a dibenzocyclooctyne (DBCO) moiety. 5-TAMRA-DBCO is able to copper-free click chemistry reactions with azide-functionalized molecules. 5-TAMRA-DBCO can be used for labeling proteins, peptides, nucleic acids (Ex/Em = 541/567 nm) .
    5-TAMRA-DBCO
  • HY-151859A
    N3-Gly-Gly-OH DCHA

    		Biochemical Assay Reagents Others
    N3-Gly-Gly-OH DCHA is a click chemistry reagent containing an azide group. N3-Gly-Gly-OH DCHA undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing an alkyne group. N3-Gly-Gly-OH DCHA also undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. N3-Gly-Gly-OH DCHA can be used to construct peptide-like ADC linkers via click chemistry .
    N3-Gly-Gly-OH DCHA
  • HY-151786
    Fmoc-L-Lys(Pentynoyl-DIM)-OH

    		ADC Linker Others
    Fmoc-L-Lys(Pentynoyl-DIM)-OH is a click chemistry reagent containing an azide. Fmoc-L-Lys(Pentynoyl-DIM)-OH can be used as a SPPS building block for the “helping hand” strategy for purification of highly insoluble peptides. Solubilizing residues are attached to the Lys side-chains using Click-chemistry. The solubilizing tag can be removed with 1M hydrazine or hydroxylamine solution . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    Fmoc-L-Lys(Pentynoyl-DIM)-OH
  • HY-153486
    N3-VC-PAB-PNP

    		Biochemical Assay Reagents Others
    N3-VC-PAB-PNP is the intermediate of bicyclic peptide ligand STING conjugates . N3-VC-PAB-PNP is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    N3-VC-PAB-PNP
  • HY-W781921
    BP Fluor 488 Alkyne

    		Fluorescent Dye Others
    BP Fluor 488 Alkyne is a popular labeling dye used in Click Chemistry reactions. It will react with the azide group in antibody, proteins, peptides, amino-modified oligos, and other target molecules. The dye has an excitation peak at 499 nm and an emission peak at 520 nm. The conjugates are widely used in microscopy, flow cytometry, and other applications. BP Fluor 488 is a pure 5-sulfonated rhodamine molecule and it eliminates the lot-to-lot variation caused by two isomers ratio differences.
    BP Fluor 488 Alkyne
  • HY-151678
    N3-L-Lys(Mtt)-OH

    		ADC Linker Others
    N3-L-Lys(Mtt)-OH is a click chemistry reagent containing an azide group. N3-L-Lys(Mtt)-OH can introduce azide functions into the amino acid building block of peptide sequences at the N-terminal position. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    N3-L-Lys(Mtt)-OH
  • HY-145934B
    UDP-GlcNAz

    		OGT Biochemical Assay Reagents Glycosidase Metabolic Disease
    UDP-GlcNAz is the analogue of UDP-GlcNAc disodium (HY-112174). UDP-GlcNAc disodium is the donor substrate of many N-acetylgalactosaminyltransferases, enzymes which transfer GlcNAc from the nucleotide sugar to a saccharide or peptide acceptor. UDP-GlcNAc disodium is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .
    UDP-GlcNAz
  • HY-151824
    Boc-L-Phe(4-NH-Poc)-OH

    		ADC Linker Others
    Boc-L-Phe(4-NH-Poc)-OH is a click chemistry reagent containing an azide group. Used as an orthogonally protected building block in peptide synthesis. Propargyloxycarbonyl, commonly abbreviated as Poc or Pryoc, can either be used as alkyne component for standard Click conjugation or in combination with tetrazine linkers in copper-free Diels-Alder type Click reactions. It also has applications as unusual protecting group for amines, hydroxy functions and as esters. All 3 are stable to neat TFA, but can be cleaved at ambient temperature with Co2(CO)8 in TFA:DCM. Deprotection with other transition metals like palladium have also been reported . Boc-L-Phe(4-NH-Poc)-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Boc-L-Phe(4-NH-Poc)-OH
  • HY-151826
    Fmoc-D-Lys(pentynoyl)-OH

    		ADC Linker Others
    Fmoc-D-Lys(pentynoyl)-OH is a click chemistry reagent containing an azide group. Used to introduce alkyne functionality into peptides that can be further modified using Click-chemistry .
    Fmoc-D-Lys(pentynoyl)-OH
  • HY-W142064
    Fmoc-L-photo-proline

    		Antibiotic Others
    Fmoc-L-photo-proline is a photo-crosslinking amino acid which can be incorporated into synthetic peptides using solid-phase Fmoc chemistry. Fmoc-L-photo-proline can synthesis of cyclic peptidomimetic antibiotic and be used for preparation of diverse peptide-based photoaffinity probes research .
    Fmoc-L-photo-proline
  • HY-W451405
    2,5-Dioxopyrrolidin-1-yl hept-6-ynoate

    		Biochemical Assay Reagents Others
    2,5-Dioxopyrrolidin-1-yl hept-6-ynoate is an amine reactive four carbon reagent that can be used for derivatizing peptides, antibodies, amine coated surfaces etc. The alkyne group reacts with azide-bearing compounds or biomolecules in copper catalyzed Click Chemistry reactions.
    2,5-Dioxopyrrolidin-1-yl hept-6-ynoate
  • HY-151780
    Fmoc-L-Dap(Pentynoyl)-OH

    		ADC Linker Others
    Fmoc-L-Dap(Pentynoyl)-OH is a click chemistry reagent containing an azide group. Fmoc-L-Dap(Pentynoyl)-OH serves as an amino acid building block for introducing alkyne functions into peptide sequences by standard Fmoc/tBu protocols. The alkyne residue can be engaged for copper catalyzed click reaction with organic azides or with tetrazines for copper-free conjugations . Fmoc-L-Dap(Pentynoyl)-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Fmoc-L-Dap(Pentynoyl)-OH
  • HY-W800680
    BP Fluor 488 DBCO

    		Fluorescent Dye Others
    BP Fluor 488 DBCO is a popular labeling dye used in copper-free Click Chemistry reactions. It will react with the azide group in antibody, proteins, peptides, amino-modified oligos, and other target molecules. The dye has an excitation peak at 499 nm and an emission peak at 520 nm. The conjugates are widely used in microscopy, flow cytometry, and other applications. BP Fluor 488 is a pure 5-sulfonated rhodamine molecule and it eliminates the lot-to-lot variation caused by two isomers ratio differences.
    BP Fluor 488 DBCO
  • HY-151837
    H-L-Phe(4-NH-Poc)-OH hydrochloride

    		ADC Linker Others
    H-L-Phe(4-NH-Poc)-OH (hydrochloride) is a click chemistry reagent containing an azide group. Used as a modified Phe or Tyr analogue in protein and peptide biosynthesis. Propargyloxycarbonyl, commonly abbreviated as Poc or Pryoc, can either be used as alkyne component for standard Click conjugation or in combination with tetrazine linkers in copper-free Diels-Alder type Click reactions. It also has applications as unusual protecting group for amines, hydroxy functions and as esters. All 3 are stable to neat TFA, but can be cleaved at ambient temperature with Co2(CO)8 in TFA:DCM. Deprotection with other transition metals like palladium have also been reported . H-L-Phe(4-NH-Poc)-OH (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    H-L-Phe(4-NH-Poc)-OH hydrochloride
  • HY-140739A
    DSPE-PEG2000-Maleimide free acid

    		Liposome Neurological Disease Cancer
    DSPE-PEG2000-Maleimide free acid is a phospholipid-PEG conjugate. DSPE-PEG2000-Maleimide free acid utilizes the amphiphilicity of DSPE to insert into the lipid bilayer of liposomes or nanoparticles. DSPE-PEG2000-Maleimide free acid covalently couples to the sulfhydryl (-SH) of ligands (such as antibodies, peptides, or proteins) via thiol-maleimide click chemistry, giving the particles targeting capabilities. DSPE-PEG2000-Maleimide free acid can be used in the researches of breast cancer, lymphoma, and inherited retinal degeneration .
    DSPE-PEG2000-Maleimide free acid
  • HY-151738
    Fmoc-Aeg(N3)-OH

    		ADC Linker Others
    Fmoc-Aeg(N3)-OH is a click chemistry reagent containing an Azide. Alkylating the Nitrogen of an amide bond results in peptoid structures, which leads to conformational restrains, like N-methylation and allows backbone derivatisation. Altering cytotoxicity, bacterial cell selectivity and receptor pharmacology through formation of peptoid derivatives have been published for Cilengitide, Piscidin 1, and MC3, MC4 and MC5 receptor agonist. This building block enables design of macrocycles through intermolecular crosslinking or backbone stabilization through intermolecular ring-closure. This compound is a potential building block for the construction of (customized) peptide nucleic acids (PNAs) and for peptoid synthesis . Fmoc-Aeg(N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    Fmoc-Aeg(N3)-OH
  • HY-151783A
    DAPOA DCHA

    		ADC Linker Others
    DAPOA DCHA is a click chemistry reagent containing an azide. DAPOA DCHA can be used in peptide synthesis as a linker that can be further modified at the azido-groups using Staudinger ligation or click-chemistry. This material can be used as a building block for dendrimeric structures . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    DAPOA DCHA
  • HY-151825
    Fmoc-L-Phe(4-NH-Poc)-OH

    		ADC Linker Others
    Fmoc-L-Phe(4-NH-Poc)-OH is a click chemistry reagent containing an azide group. Used as an orthogonally protected building block in solid-phase peptide synthesis. Poc-group can be further modified using Click-chemistry .
    Fmoc-L-Phe(4-NH-Poc)-OH
  • HY-W800724
    Methyltetrazine-PEG4-DBCO

    		Biochemical Assay Reagents Others
    Methyltetrazine-PEG4-DBCO is a PEG linker with a terminal TCO reactive reagent and a DBCO group. DBCO is commonly used for copper-free Click Chemistry reactions. Methyltetrazine can be used to convert azido-containing peptides or proteins into tetrazine-modified peptides or protein without catalyst or axillary reagents.
    Methyltetrazine-PEG4-DBCO
  • HY-172513
    Methyltetrazine-PEG11-DBCO

    		Biochemical Assay Reagents Others
    Methyltetrazine-PEG11-DBCO is a TCO reactive reagent with a DBCO group and water-soluble PEG spacer. This reagent can be used to convert azido-containing peptides or proteins into tetrazine-modified peptides or protein without catalyst or axillary reagents. DBCO is commonly used for copper-free Click Chemistry reactions.
    Methyltetrazine-PEG11-DBCO
  • HY-W800723
    Methyltetrazine-PEG2-DBCO

    		Biochemical Assay Reagents Others
    Methyltetrazine-PEG2-DBCO is a TCO reactive reagent with a DBCO group and water-soluble PEG spacer. This reagent can be used to convert azido-containing peptides or proteins into tetrazine-modified peptides or protein without catalyst or axillary reagents. DBCO is commonly used for copper-free Click Chemistry reactions.
    Methyltetrazine-PEG2-DBCO
  • HY-151787
    Fmoc-L-Lys(N3-Aca-DIM)-OH

    		ADC Linker Others
    Fmoc-L-Lys(N3-Aca-DIM)-OH is a click chemistry reagent containing an azide group. Used as a SPPS building-block for the “helping hand” strategy for purification of highly insoluble peptides. Solubilizing residues are attached to the Lys side-chains using Click-chemistry. The solubilizing tag can be removed with 1M hydrazine or hydroxylamine solution . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    Fmoc-L-Lys(N3-Aca-DIM)-OH
  • HY-D0820A
    CY5-YNE triethylamine

    Sulfo-Cyanine5-alkyne triethylamine

    		 Fluorescent Dye Others
    CY5-YNE (Sulfo-Cyanine5-alkyne) triethylamine is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides (Ex: 650 nM; Em: 680 nm). CY5-YNE triethylamine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    CY5-YNE triethylamine
  • HY-147206
    Biotin-PEG600-Alk

    		Fluorescent Dye Others
    Biotin-PEG600-Alk is a Biotin-labeled Alkyne functionalized polyethylene glycol. Biotin-PEG600-Alk can be used to modify proteins, peptides, and oligonucleotides . Biotin-PEG600-Alk is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Biotin-PEG600-Alk
  • HY-112295
    AzKTB

    		Biochemical Assay Reagents Infection
    AzKTB is a capture reagent which bears a short trypsin-cleavable peptide sequence between the azide module and the TAMRA/PEG-biotin labels. AzKTB is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    AzKTB
  • HY-151778
    Fmoc-Abg(N3)-OH

    		ADC Linker Others
    Fmoc-Abg(N3)-OH is a click chemistry reagent containing an azide group. Fmoc-Abg(N3)-OH has the potential to synthesize peptide nucleic acids (PNA) and peptoids. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    Fmoc-Abg(N3)-OH
  • HY-P0132A
    YIGSR-Lys(N3)

    		NO Synthase Cancer
    YIGSR-Lys(N3) is a peptide that can inhibit the tumour growth and metastasis of leukaemic cells. YIGSR blocks the cellular binding to laminin I via a 67-kDa laminin-binding protein, and inhibits shear-induced increase in eNOS expression of laminin cells . YIGSR-Lys(N3) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    YIGSR-Lys(N3)
  • HY-W800702
    BP Fluor 555 azide

    		Fluorescent Dye Others
    BP Fluor 555 Azide is a water-soluble, bright orange-fluorescent dye with excitation ideally suited for the 532 nm or 555 nm laser lines and visualized with TRITC (tetramethylrhodamine) filter sets. BP Fluor 555 conjugates of antibodies, peptides, and proteins are pH insensitive from pH 4 to pH 10. AF 555 conjugates ideally suited for detection of low abundance targets. BP Fluor 555 Azide can be reacted with terminal alkynes via a copper-catalyzed click reaction (CuAAC). It also reacts with strained cyclooctyne via a copper-free “click chemistry” reaction to form a stable triazole and does not require Cu-catalyst or elevated temperatures. The brightness and photostability of this dye are best suited to direct imaging of low-abundance targets.
    BP Fluor 555 azide
  • HY-W090637
    N,N-Bis(phenylmethyl)-L-serine methyl ester

    		Biochemical Assay Reagents Others
    N,N-Bis(phenylmethyl)-L-serine methyl ester is a biochemical assay reagent used in peptide chemistry.
    N,N-Bis(phenylmethyl)-L-serine methyl ester
  • HY-P11755
    DBCO-P-LPK

    		Drug Intermediate Cancer
    DBCO-P-LPK is a DBCO-modified colorectal cancer-specific binding peptide that serves as a key intermediate for targeted anticancer conjugates. DBCO-P-LPK enables the synthesis of the P-LPK-Camptothecin (HY-16560) conjugate. DBCO-P-LPK is applicable to the research of colorectal cancer .
    DBCO-P-LPK
  • HY-W451460
    2,5-Dioxopyrrolidin-1-yl 2-(prop-2-yn-1-yloxy)acetate

    		Biochemical Assay Reagents Others
    2,5-Dioxopyrrolidin-1-yl 2-(prop-2-yn-1-yloxy)acetate is a Click Chemistry reagent with a propargyl group and an NHS ester group. The propargyl group can react with biomolecules containing azide group via copper catalyzed Click Chemistry reaction. The NHS ester is an amine reactive group which can be used for derivatizing peptides, antibodies, amine coated surfaces, etc.
    2,5-Dioxopyrrolidin-1-yl 2-(prop-2-yn-1-yloxy)acetate
  • HY-185423
    PreQ1-DBCO

    		DNA/RNA Synthesis Biochemical Assay Reagents Cardiovascular Disease
    PreQ1-DBCO is a strained cyclooctyne commonly used in click chemistry. PreQ1-DBCO undergoes TGT-catalyzed guanine base exchange in DNA oligonucleotide stem-loops to replace guanine. PreQ1-DBCO functionalizes custom DNA oligonucleotide sequences. DBCO-modified DNA oligonucleotides are conjugated with azide peptides via strain-promoted azide-alkyne click chemistry (SPAAC). PreQ1-DBCO can be used in studies of hemophilia B (Christmas disease) .
    PreQ1-DBCO
  • HY-183038
    2-Phenyl-1-octen-7-yn-1-one

    		Biochemical Assay Reagents Others
    2-Phenyl-1-octen-7-yn-1-one is an alkyne-functionalized enone with site-selective reactivity toward the N-terminal α-amino group of peptides and proteins. 2-Phenyl-1-octen-7-yn-1-one can undergo click chemistry with azides via its alkyne moiety to enable further protein functionalization. 2-Phenyl-1-octen-7-yn-1-one modifies unprotected peptide libraries as well as proteins including insulin, lysozyme, RNaseA and BCArg .
    2-Phenyl-1-octen-7-yn-1-one
  • HY-108010
    Aftobetin

    		Amyloid-β Neurological Disease
    Aftobetin is a non-invasive molecular probe used for the early diagnosis of Alzheimer's disease (AD). Aftobetin can specifically bind to the aggregated β-amyloid peptide (Aβ) in the lens of the eye, enabling the early diagnosis of AD through a rapid and painless detection method .
    Aftobetin

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