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  2. Fluorescent Dye
  3. 5-TAMRA-DBCO

5-TAMRA-DBCO is a fluorescent dye that combines 5-TAMRA (HY-15942) with a dibenzocyclooctyne (DBCO) moiety. 5-TAMRA-DBCO is able to copper-free click chemistry reactions with azide-functionalized molecules. 5-TAMRA-DBCO can be used for labeling proteins, peptides, nucleic acids (Ex/Em = 541/567 nm).

For research use only. We do not sell to patients.

5-TAMRA-DBCO

5-TAMRA-DBCO Chemical Structure

CAS No. : 2071694-39-6

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Solid
5 mg In-stock
10 mg In-stock
25 mg In-stock
50 mg In-stock
100 mg In-stock
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500 mg   Get quote  

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Description

5-TAMRA-DBCO is a fluorescent dye that combines 5-TAMRA (HY-15942) with a dibenzocyclooctyne (DBCO) moiety. 5-TAMRA-DBCO is able to copper-free click chemistry reactions with azide-functionalized molecules. 5-TAMRA-DBCO can be used for labeling proteins, peptides, nucleic acids (Ex/Em = 541/567 nm)[1].

Molecular Weight

688.77

Formula

C43H36N4O5

CAS No.
Appearance

Solid

Color

Purple to purplish red

SMILES

O=C1OC2(C3=CC=C(C(NCCC(N4C5=C(C#CC6=C(C4)C=CC=C6)C=CC=C5)=O)=O)C=C13)C7=CC=C(N(C)C)C=C7OC8=CC(N(C)C)=CC=C82

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (145.19 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4519 mL 7.2593 mL 14.5186 mL
5 mM 0.2904 mL 1.4519 mL 2.9037 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.4519 mL 7.2593 mL 14.5186 mL 36.2966 mL
5 mM 0.2904 mL 1.4519 mL 2.9037 mL 7.2593 mL
10 mM 0.1452 mL 0.7259 mL 1.4519 mL 3.6297 mL
15 mM 0.0968 mL 0.4840 mL 0.9679 mL 2.4198 mL
20 mM 0.0726 mL 0.3630 mL 0.7259 mL 1.8148 mL
25 mM 0.0581 mL 0.2904 mL 0.5807 mL 1.4519 mL
30 mM 0.0484 mL 0.2420 mL 0.4840 mL 1.2099 mL
40 mM 0.0363 mL 0.1815 mL 0.3630 mL 0.9074 mL
50 mM 0.0290 mL 0.1452 mL 0.2904 mL 0.7259 mL
60 mM 0.0242 mL 0.1210 mL 0.2420 mL 0.6049 mL
80 mM 0.0181 mL 0.0907 mL 0.1815 mL 0.4537 mL
100 mM 0.0145 mL 0.0726 mL 0.1452 mL 0.3630 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
5-TAMRA-DBCO
Cat. No.:
HY-D2891
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