N3-Gly-Gly-OH
Based on 1 Customer Validation
N3-Gly-Gly-Gly-OH is a click chemistry reagent containing an azide group. N3-Gly-Gly-OH undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing an alkyne group. N3-Gly-Gly-OH also undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. N3-Gly-Gly-Gly-OH can be used to construct peptide-like ADC linkers via click chemistry.
For research use only. We do not sell to patients.
- Purity: 98.40%
- CAS No.: 855750-87-7
- Formula: C4H6N4O3
- Molecular Weight:158.12
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Storage:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
N3-Gly-Gly-OH undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing an Alkyne group; it also undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing a DBCO or BCN group[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 855750-87-7
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Appearance Liquid
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Molecular Weight 158.12
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Formula C4H6N4O3
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Color Colorless to light yellow
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SMILES
[N-]=[N+]=NCC(NCC(O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 250 mg/mL (1581.08 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : 125 mg/mL (790.54 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| H2O / DMSO | 1 mM | 6.3243 mL | 31.6216 mL | 63.2431 mL | 158.1078 mL |
| 5 mM | 1.2649 mL | 6.3243 mL | 12.6486 mL | 31.6216 mL | |
| 10 mM | 0.6324 mL | 3.1622 mL | 6.3243 mL | 15.8108 mL | |
| 15 mM | 0.4216 mL | 2.1081 mL | 4.2162 mL | 10.5405 mL | |
| 20 mM | 0.3162 mL | 1.5811 mL | 3.1622 mL | 7.9054 mL | |
| 25 mM | 0.2530 mL | 1.2649 mL | 2.5297 mL | 6.3243 mL | |
| 30 mM | 0.2108 mL | 1.0541 mL | 2.1081 mL | 5.2703 mL | |
| 40 mM | 0.1581 mL | 0.7905 mL | 1.5811 mL | 3.9527 mL | |
| 50 mM | 0.1265 mL | 0.6324 mL | 1.2649 mL | 3.1622 mL | |
| 60 mM | 0.1054 mL | 0.5270 mL | 1.0541 mL | 2.6351 mL | |
| 80 mM | 0.0791 mL | 0.3953 mL | 0.7905 mL | 1.9763 mL | |
| 100 mM | 0.0632 mL | 0.3162 mL | 0.6324 mL | 1.5811 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
N3-Gly-Gly-OH Related Classifications
HY-151859 Related Classifications
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